Transarterial Chemoembolization / TumCG Cancer Research Results

TACE, Transarterial Chemoembolization: Click to Expand ⟱
Features:
TACE, which stands for Transarterial Chemoembolization—a treatment primarily used for certain types of cancer, most notably liver cancer (hepatocellular carcinoma).

TACE is a minimally invasive procedure that involves delivering chemotherapy directly into the artery that supplies blood to a tumor (most commonly in the liver) and then injecting substances to block (embolize) the artery. This dual action attacks the tumor by:
-Concentrating chemotherapy at the site of the tumor.
-Restricting the tumor’s blood supply, which helps to starve the cancer cells of oxygen and nutrients.

How It Works:
-Catheter Insertion: A catheter is inserted through a small incision, usually in the groin, and navigated into the arterial system to reach the hepatic artery (if treating liver cancer).
-Chemotherapy Delivery: A concentrated dose of chemotherapy is delivered directly into the blood vessels feeding the tumor.
-Embolization: Embolic agents (such as gelatin sponge particles, microspheres, or other embolic materials) are then injected to block the artery, thereby limiting the tumor’s blood flow.
TumCG, Tumor cell growth: Click to Expand ⟱
Source:
Type:
Normal cells grow and divide in a regulated manner through the cell cycle, which consists of phases (G1, S, G2, and M).
Cancer cells often bypass these regulatory mechanisms, leading to uncontrolled proliferation. This can result from mutations in genes that control the cell cycle, such as oncogenes (which promote cell division) and tumor suppressor genes (which inhibit cell division).
Scientific Papers found: Click to Expand⟱
2485- VitC,  TACE,    High-Dose Vitamin C Promotes Regression of Multiple Pulmonary Metastases Originating from Hepatocellular Carcinoma
- Case Report, HCC, NA
ROS↑, Dose↝, Dose↝, TumCG↓, Remission↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 2,  

Functional Outcomes ⓘ

Remission↑, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TumCG, Tumor cell growth
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:326  Target#:323  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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