Potassium / IL6 Cancer Research Results

K+, Potassium: Click to Expand ⟱
Features:
Potassium (K⁺), an essential electrolyte, plays vital roles in cellular function, neuronal signaling, and maintaining membrane potential.
-Source: leafy vegs, legumes, salmon(384mg), banana(358mg), potatoes(russet in skin)(550mg)
-RDA: 4700mg/d (<2% of US adults meet this goal)
AD:
-Low extracellular potassium can lead to increased neuronal calcium influx, oxidative damage, and microglial activation, worsening neurodegeneration.
-Certain potassium channels (e.g., KCNQ) are downregulated in AD, and their activators (like retigabine) have shown neuroprotective effects in preclinical models.

Cancer:
-K⁺ channels upregulated in many cancers

Those with kidney problems, may need to decrease potassium intake.
IL6, Interleukin-6: Click to Expand ⟱
Source: HalifaxProj(inhibit)
Type:
Interleukin-6 (IL-6) is a cytokine that plays a significant role in inflammation and the immune response. It is produced by various cell types, including T cells, B cells, macrophages, and fibroblasts.
IL-6 can promote tumor cell proliferation and survival. Many cancer cells produce IL-6, which can create an autocrine loop that supports their growth.
IL-6 is a high-value inflammatory biomarker in cancer, reporting cytokine burden, catabolic stress, and STAT3-linked survival signaling. While not tumor-specific, elevated and rising IL-6 strongly predicts poor prognosis and limited treatment tolerance, making it an important system-state indicator alongside CRP and ferritin.


Scientific Papers found: Click to Expand⟱
4007- K+,    The increased potassium intake improves cognitive performance and attenuates histopathological markers in a model of Alzheimer's disease
- in-vivo, AD, NA
*p‑tau↓, *cognitive↑, *Inflam↓, *ROS↓, *IL6↓, *4-HNE↓, *other↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

4-HNE↓, 1,   ROS↓, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

Immune & Inflammatory Signaling ⓘ

IL6↓, 1,   Inflam↓, 1,  

Synaptic & Neurotransmission ⓘ

p‑tau↓, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,  

Functional Outcomes ⓘ

cognitive↑, 1,  
Total Targets: 8

Scientific Paper Hit Count for: IL6, Interleukin-6
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:357  Target#:158  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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