Germacranolide / TumCP Cancer Research Results

Ger, Germacranolide: Click to Expand ⟱

Features:

A germacranolide sesquiterpene lactone (GSL) was isolated from Siegesbeckia glabrescens

TumCP, Tumor Cell proliferation: Click to Expand ⟱

Source:

Type:

Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors.

Scientific Papers found: Click to Expand⟱

30-

Ger,

A sesquiterpene lactone from Siegesbeckia glabrescens suppresses Hedgehog/Gli-mediated transcription in pancreatic cancer cells

in-vitro,

PC,

PANC1

 (IC 50) values of 6,.9 uM

in-vitro,

PC,

AsPC-1

 5.1 uM

HH↓, Gli1↓, Shh↓, cycD1/CCND1↓, TumCP↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Cycle & Senescence ⓘ

cycD1/CCND1↓, 1,

Proliferation, Differentiation & Cell State ⓘ

Gli1↓, 1, HH↓, 1, Shh↓, 1,

Migration ⓘ

TumCP↓, 1,
Total Targets: 5

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: TumCP, Tumor Cell proliferation

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells