Ach Cancer Research Results

Ach, Acetylcholine: Click to Expand ⟱
Source:
Type:
Acetylcholine (ACh) 
↓ Acetylcholine (ACh) levels in AD patients


Scientific Papers found: Click to Expand⟱
8140- LF,    Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival
- in-vitro, NSCLC, A549 - in-vitro, NSCLC, H1299
P53↑, Treatment of A549 cells with Lf led to ~ 1.50‐fold activation of p53, ~ 1.60‐fold activation of AChE, and ~ 1.80‐fold decrease in ACh levels.
AChE↑,
Ach↓,
VEGF↓, (VEGF) levels also decreased in cell culture supernatants upon treatment with Lf in both cell lines
Akt↓, AKT activity decreased ~ 1.95‐fold in A549 cells and ~ 1.50‐fold in H1299 cells.


Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death(tgid=5) ⓘ

Akt↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

VEGF↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↑, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Ach, Acetylcholine
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1347  State#:%  Dir#:1
  wNotes=on  sortOrder:rid,rpid

 

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