CIT Cancer Research Results

CIT, chemotherapy-induced thrombocytopenia (CIT): Click to Expand ⟱
Source:
Type:

chemotherapy-induced thrombocytopenia (CIT)
Scientific Papers found: Click to Expand⟱
6374- CPLE,    Antiviral & platelet-protective properties of Carica papaya in dengue
- Review, Nor, NA
*antiOx↑, The antioxidants present in papaya leaves act by reducing lipid peroxidation, and also exhibit anti-tumour and immunomodulatory effects.
*lipid-P↓,
*AntiTum↑,
Imm↑,
CIT↓, revealed that oral uptake of a tablet containing CPLE (1100 mg) three times a day for five days significantly increased platelet counts compared to the placebo group.

6370- CPLE,    Delving into the Therapeutic Potential of Carica papaya Leaf against Thrombocytopenia
- Review, Var, NA
CIT↓, Carica papaya leaf has unique therapeutic and medicinal characteristics against thrombocytopenia, and this is supported by scientific studies.
*Imm↑, therapeutic benefits of the leaf include immunomodulatory, antiviral, antidiabetic, anticancer, antimalarial, antiangiogenic, antibacterial, and antioxidant activities.
*AntiDiabetic↑,
*AntiCan↑,
angioG↓,
*Bacteria↓,
*antiOx↑,

6369- CPLE,    Carica papaya leaf extract (CPLE) versus placebo to improve chemotherapy induced thrombocytopenia (CIT): Results of a phase III triple blinded, randomized placebo controlled trial (PACT study).
- Trial, Var, NA
PC↑, Carica papaya leaf extract (CPLE) is known to increase platelet counts (PC) in certain infections. significantly improved by CPLE (83/129, 64% vs 33/69, 48%; p = 0.034) as compared to placebo
other↝, CPLE is the first therapeutic intervention that appears to improve grade 2 and grade 3 chemotherapy induced thrombocytopenia faster and to a greater extent than placebo in this phase III randomized trial.
CIT↓, improve chemotherapy induced thrombocytopenia (CIT):


Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

CIT↓, 3,   PC↑, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,  

Immune & Inflammatory Signaling ⓘ

Imm↑, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   lipid-P↓, 1,  

Immune & Inflammatory Signaling ⓘ

Imm↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 1,   AntiTum↑, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 7

Scientific Paper Hit Count for: CIT, chemotherapy-induced thrombocytopenia (CIT)
3 Carica papaya leaf extract
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1482  State#:%  Dir#:1
  wNotes=on  sortOrder:rid,rpid

 

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