SBF2-AS1 Cancer Research Results

SBF2-AS1, SET Binding Factor 2 Antisense RNA 1: Click to Expand ⟱
Source:
Type:

SBF2-AS1 - SET Binding Factor 2 Antisense RNA 1

Type: Long non-coding RNA / antisense RNA / post-transcriptional and epigenetic regulator

Function: SBF2-AS1 is a long non-coding RNA located antisense to the SBF2 gene. It regulates gene expression through mechanisms including microRNA sequestration, modulation of target mRNA expression, and interactions with chromatin-regulatory complexes such as PRC2. Through these mechanisms, SBF2-AS1 can influence cell-cycle progression, proliferation, migration, invasion, metastasis, angiogenesis, and treatment response.

Cancer: ↑ Frequently overexpressed in multiple cancers and predominantly functions as an oncogenic lncRNA. High SBF2-AS1 expression is associated with increased tumor size, advanced stage, lymph-node and distant metastasis, poorer differentiation, and unfavorable survival. SBF2-AS1 promotes proliferation, migration, invasion, metastasis, and treatment resistance through multiple miRNA-target axes and epigenetic mechanisms. SBF2-AS1 inhibition generally suppresses malignant behavior in experimental models.
Scientific Papers found: Click to Expand⟱
8165- LapC,    Lapachol interferes with the cell cycle and inhibits proliferation and migration of bladder tumor cells with effects on ncRNA expression
- in-vitro, Bladder, RT4
tumCV↓, TumCMig↓, TumCCA↑, SBF2-AS1↓, JHDM1D-AS1↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

JHDM1D-AS1↓, 1,   SBF2-AS1↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Migration(tgid=13) ⓘ

TumCMig↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SBF2-AS1, SET Binding Factor 2 Antisense RNA 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1770  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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