dibenzyl trisulphide(DTS) from Anamu / Th2 Cancer Research Results

Anamu, dibenzyl trisulphide(DTS) from Anamu: Click to Expand ⟱
Features:
Anamu (Guinea Hen Weed) Anamu (Petiveria alliacea)
A herb that is indigenous to the Amazon rainforest and the tropical areas of the Caribbean, Central and South America and Africa.
Anamu has been used for a wide variety of conditions, including arthritis, digestive disorders, infections, diabetes, cancer, for pain relief, and to induce abortion.
Th2, Type 2 helper cell: Click to Expand ⟱
Source:
Type:
Type 2 helper cell (Th2) pathway is a subset of the immune response that plays a crucial role in the regulation of inflammation, allergies, and parasitic infections.
Key cytokines involved in the Th2 pathway: IL-4, IL-13, IL-5, IL-9.

Elevated levels of certain Th2 cytokines (e.g., IL-10) can suppress cytotoxic T cell responses, thereby impairing effective antitumor immunity.

In several cancers (such as ovarian, gastric, and certain breast cancers), high levels of Th2 cytokines or an increased Th2 cell infiltration have been observed.
 - The relative balance between Th1 and Th2 responses is critical, with a Th2-skewed response often suggesting a shift away from effective cytotoxic antitumor immunity.

A predominant Th2 environment is frequently linked to worse prognostic features, including enhanced tumor progression, increased metastasis, and reduced overall survival in some cancer types.
Scientific Papers found: Click to Expand⟱
552- Anamu,    A critical review of the therapeutic potential of dibenzyl trisulphide isolated from Petiveria alliacea L (guinea hen weed, anamu)
- Review, NA, NA
p‑MAPK↑, Th1 response↓, Th2↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

p‑MAPK↑, 1,  

Immune & Inflammatory Signaling ⓘ

Th1 response↓, 1,   Th2↑, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Th2, Type 2 helper cell
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:193  Target#:787  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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