Trichostatin A / Apoptosis Cancer Research Results

TSA, Trichostatin A: Click to Expand ⟱

Features:

Trichostatin A (TSA) is a naturally occurring compound that belongs to the class of histone deacetylase inhibitors (HDACis).
TSA has been shown to induce apoptosis (programmed cell death) in various cancer cell lines, including leukemia, breast, and lung cancer cells.

Apoptosis, Apoptosis: Click to Expand ⟱

Source:

Type: type of cell death

Situation in which a cell actively pursues a course toward death upon receiving certain stimuli.
Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die.

Scientific Papers found: Click to Expand⟱

326-

AgNPs,

TSA,

Modulating chromatin structure and DNA accessibility by deacetylase inhibition enhances the anti-cancer activity of silver nanoparticles

in-vitro,

Cerv,

HeLa

Apoptosis↑, ChrMod↝, eff↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death ⓘ

Apoptosis↑, 1,

Transcription & Epigenetics ⓘ

ChrMod↝, 1,

Drug Metabolism & Resistance ⓘ

eff↑, 1,
Total Targets: 3

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: Apoptosis, Apoptosis

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells