Mushroom Reishi / NK cell Cancer Research Results

MushReishi, Mushroom Reishi: Click to Expand ⟱

Features:

Reishi mushroom (Ganoderma lucidum)
-Various compounds such as glycoproteins, polysaccharides, triterpenoids, meroterpenoids, sesquiterpenoids, steroids, alkaloids, benzopyran derivatives, and benzoic acid derivatives, and minerals such as potassium, calcium, phosphorus, magnesium, selenium, iron and zinc.
-Most important polysaccharides and triterpenes.
-Polysaccharides, especially beta-glucans (ability to support immune system function)

Higher bioavailability in liquid form

Pathways
-Enhances activity of natural killer (NK) cells, dendritic cells, and T lymphocytes -NF-κB Inhibition

NK cell, NK cell activity: Click to Expand ⟱

Source: HalifaxProj(promote)

Type:

Natural Killer (NK) cells are a type of lymphocyte in the immune system that play a crucial role in the body's defense against tumors and virally infected cells.
NK cells can directly kill cancer cells through the release of cytotoxic granules containing perforin and granzymes. Perforin forms pores in the target cell membrane, allowing granzymes to enter and induce apoptosis (programmed cell death).
NK cells produce various cytokines, such as interferon-gamma (IFN-γ), which can enhance the immune response and promote the activation of other immune cells, including macrophages and T cells.
-Monoclonal Antibodies: Using antibodies that engage NK cells to target and kill cancer cells.
-Cytokine Therapy: Administering cytokines like IL-2 or IL-15 to boost NK cell activity.

Scientific Papers found: Click to Expand⟱

1573-

MushReishi,

Ganoderma lucidum (Reishi mushroom) for cancer treatment

Review,

NA,

A total of five RCTs with 373 subjects were included in this review

ChemoSen↑, CR3↝, eff↑, NK cell↑, T-Cell↑, QoL↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Immune & Inflammatory Signaling ⓘ

CR3↝, 1, NK cell↑, 1, T-Cell↑, 1,

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1, eff↑, 1,

Functional Outcomes ⓘ

QoL↑, 1,
Total Targets: 6

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: NK cell, NK cell activity

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells