Glucose / eff Cancer Research Results

Gluc, Glucose: Click to Expand ⟱
Features:
Glucose is a fundamental energy source and its metabolism is essential for all cells, the reprogramming of glucose metabolism in cancer cells underlies many aspects of tumor growth and survival.
-Glucose generally aids cancer cells, but can be used as trojan horse.
-HIF-1 increases the expression of glycolytic enzymes
-Hexokinase II, which catalyzes the first step of glycolysis (often upregulated).
eff, efficacy: Click to Expand ⟱
Source:
Type:
Power to enhance an anti cancer effect
Scientific Papers found: Click to Expand⟱
2835- AgNPs,  Gluc,    Carbohydrate functionalization of silver nanoparticles modulates cytotoxicity and cellular uptake
- in-vitro, Liver, HepG2
Dose↝, eff↑, ROS↑, eff↝, eff↑, eff↝, eff↑, eff↝,
2836- AgNPs,  Gluc,    Glucose capped silver nanoparticles induce cell cycle arrest in HeLa cells
- in-vitro, Cerv, HeLa
eff↝, TumCCA↑, eff↑, eff↑, ROS↑, GSH↓, SOD↓, lipid-P↑, LDH↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

GSH↓, 1,   lipid-P↑, 1,   ROS↑, 2,   SOD↓, 1,  

Core Metabolism/Glycolysis ⓘ

LDH↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 1,   eff↑, 5,   eff↝, 4,  

Clinical Biomarkers ⓘ

LDH↑, 1,  
Total Targets: 10

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: eff, efficacy
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:335  Target#:961  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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