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Vitamin B6 (pyridoxine) has been studied in relation to Alzheimer’s disease (AD) due to its role in brain health, neurotransmitter synthesis, and homocysteine metabolism.
Biological Role of Vitamin B6
-can act as a potent antioxidant
-Essential for the production of serotonin, dopamine, GABA, and norepinephrine.
-Homocysteine regulation: B6 is a cofactor in the conversion of homocysteine to cysteine.
Elevated homocysteine levels are linked to increased AD risk and brain atrophy.
-Anti-inflammatory effects: B6 may modulate inflammation, a key factor in neurodegeneration.
-Myelin and cognitive function: Involved in myelin formation and synaptic plasticity.
-higher vitamin B6 intakes have been associated with greater grey matter volume
Cognitive support / Homocysteine lowering 10–50 mg/day Often combined with B12 and folate
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| 4061- | betaCar, | VitB12, | VitB6, | FA, | VitB3 | Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 4076- | FA, | VitE, | VitB6, | Reduced risk of Alzheimer’s disease with high folate intake: The Baltimore Longitudinal Study of Aging |
| - | Study, | AD, | NA |
| 4077- | VitB6, | FA, | VitB12, | VitD3, | VitE | Vitamin Supplementation as an Adjuvant Treatment for Alzheimer’s Disease |
| - | Review, | AD, | NA |
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Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:360 Target#:767 State#:% Dir#:4
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