RenoP Cancer Research Results

RenoP, K,Renoprotection: Click to Expand ⟱
Source:
Type:
Protects kidneys
-Same as nephroprotective
Opposite is : Nephrotoxicity is toxicity in the kidneys
Scientific Papers found: Click to Expand⟱
6194- Cuc,    Pharmacokinetics of cucurbitacin B from Trichosanthes cucumerina L. in rats
- in-vivo, Nor, NA
*BioAv↓, absolute oral bioavailability of cucurbitacin B was approximately 10%.
*Half-Life↝, maximum concentration in plasma after normalization by dose ranged from 4.85–7.81 μg/L and the time to reach maximum value was approximately within 30 min after oral dosing.
*AST∅, The results demonstrated that after treatment, neither AST nor ALT changed significantly compared to prior treatment.
*ALAT∅,
*RenoP↝, Kidney function was determined by using creatinine as a biomarker and the results demonstrated that there was no difference between pre- and post-dosing.
*Half-Life↝, The elimination half-life was calculated from intravenous data and the value was approximately 5.08 ± 2.87 h.


Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Core Metabolism/Glycolysis ⓘ

ALAT∅, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   Half-Life↝, 2,  

Clinical Biomarkers ⓘ

ALAT∅, 1,   AST∅, 1,  

Functional Outcomes ⓘ

RenoP↝, 1,  
Total Targets: 6

Scientific Paper Hit Count for: RenoP, K,Renoprotection
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1175  State#:%  Dir#:4
  wNotes=on  sortOrder:rid,rpid

 

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