CTR1 Cancer Research Results

CTR1, Copper Transporter 1: Click to Expand ⟱
Source:
Type:
CTR1 (Copper Transporter 1) is a protein that plays a crucial role in the transport of copper into cells. Copper is an essential nutrient that is required for various cellular processes, including the regulation of cell growth, differentiation, and survival.
CTR1 has been found to be overexpressed in various types of tumors, including breast, lung, colon, and prostate cancer. The overexpression of CTR1 in cancer cells has been linked to increased copper uptake, which can promote tumor growth and progression.
Scientific Papers found: Click to Expand⟱
6171- Cu,    Copper in the tumor microenvironment and tumor metastasis
- Review, Var, NA
*angioG↑, Copper (Cu), an essential micronutrient, plays an essential role in several physiological processes, including cell proliferation and angiogenesis;
other↑, Significant Cu accumulation is observed in several tumor tissues.
*ROS↑, excess Cu accumulation in the tissues facilitates reactive oxygen species (ROS) generation, and is closely associated with Wilson’s disease and neurodegeneration.‍(
CTR1↝, Cellular Cu uptake is accomplished through the Cu importer CTR1 (SLC31A1).‍
other↝, overexpression of STEAPs is observed in several types of cancers, including prostate, colon, pancreas, and breast, these observations are consistent with CTR1 being overexpressed in cancer
COX17↝, As tumor cells have a high ATP requirement, COX17 is frequently over­expressed in clinical tumor tissues and tumor cell lines.
ATOX1↝, Due to the pro-tumor activity of Atox-1, it may be a novel biomarker for breast cancer metastasis


Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics ⓘ

COX17↝, 1,  

Transcription & Epigenetics ⓘ

other↑, 1,   other↝, 1,  

Migration ⓘ

ATOX1↝, 1,  

Barriers & Transport ⓘ

CTR1↝, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Angiogenesis & Vasculature ⓘ

angioG↑, 1,  
Total Targets: 2

Scientific Paper Hit Count for: CTR1, Copper Transporter 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:844  State#:%  Dir#:4
  wNotes=on  sortOrder:rid,rpid

 

Home Page