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Vitamin B6 (pyridoxine) has been studied in relation to Alzheimer’s disease (AD) due to its role in brain health, neurotransmitter synthesis, and homocysteine metabolism.
Biological Role of Vitamin B6
-can act as a potent antioxidant
-Essential for the production of serotonin, dopamine, GABA, and norepinephrine.
-Homocysteine regulation: B6 is a cofactor in the conversion of homocysteine to cysteine.
Elevated homocysteine levels are linked to increased AD risk and brain atrophy.
-Anti-inflammatory effects: B6 may modulate inflammation, a key factor in neurodegeneration.
-Myelin and cognitive function: Involved in myelin formation and synaptic plasticity.
-higher vitamin B6 intakes have been associated with greater grey matter volume
Cognitive support / Homocysteine lowering 10–50 mg/day Often combined with B12 and folate
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| Source: |
| Type: |
| Cognitive |
| 4064- | FA, | VitB6, | VitB12, | High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial |
| - | Trial, | AD, | NA |
| 4056- | VitB12, | VitB6, | FA, | Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis |
| - | Review, | AD, | NA |
| 4065- | VitB6, | VitB12, | FA, | Vitamin B6, B12, and Folic Acid Supplementation and Cognitive Function |
| - | Review, | AD, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:360 Target#:557 State#:% Dir#:6
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