CA125 Cancer Research Results

CA125, CA125: Click to Expand ⟱
Source:
Type:
CA125 is a protein that is often measured in the blood as a tumor marker, primarily in the context of ovarian cancer.

-CA125 is most commonly used to monitor treatment response in patients already diagnosed with ovarian cancer and to detect its recurrence.
-It may be elevated in many cases of ovarian cancer, especially the epithelial type, making it a useful marker in certain clinical settings.
Scientific Papers found: Click to Expand⟱
7996- itraC,    Itraconazole in the Treatment of Aberrantly Active Hedgehog and/or PI3K Recurrent Ovarian Cancer
- Trial, Ovarian, NA
HH↓, itraconazole treatment, which has been shown to inhibit both HH and PI3K pathways.
PI3K↓,
toxicity↝, Side effects were mostly limited to grade 1–2, including fatigue, nausea, dysgeusia, dyspnea, cough, vertigo, and edema.
eff∅, Conclusions: Itraconazole monotherapy for recurrent HH and/or PI3K aberrantly active OC is an ineffective treatment.
CA125∅, CA125 levels did not correlate with the treatment outcome, but increased rapidly after ceasing treatment
other↝, While CA125 did not correlate with treatment outcome, the rapid increase in CA125 after therapy cessation suggests tumor inhibitory effects.


Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

HH↓, 1,   PI3K↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff∅, 1,  

Clinical Biomarkers(tgid=22) ⓘ

CA125∅, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↝, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CA125, CA125
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1176  State#:%  Dir#:6
  wNotes=on  sortOrder:rid,rpid

 

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