Database Query Results : Saikosaponin B1 and D, ,

SS, Saikosaponin B1 and D: Click to Expand ⟱
Features:
Saikosaponin B1 (SSB1) and Saikosaponin D (SSD), two bioactive constituents of Radix Bupleuri
Scientific Papers found: Click to Expand⟱
107- SS,    Saikosaponin B1 and Saikosaponin D inhibit tumor growth in medulloblastoma allograft mice via inhibiting the Hedgehog signaling pathway
- vitro+vivo, MB, NA
HH↓, Smo↓, Gli↓, Gli1↓, PTCH1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Proliferation, Differentiation & Cell State ⓘ

Gli↓, 1,   Gli1↓, 1,   HH↓, 1,   PTCH1↓, 1,   Smo↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:145  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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