Database Query Results : Bicalutamide, ,

Bical, Bicalutamide: Click to Expand ⟱
Features:
Bicalutamide brand name Casodex. An antiandrogen medication that is primarily used to treat prostate cancer.
Scientific Papers found: Click to Expand⟱
2502- Bical,    Complete Response of Metastatic Androgen Receptor–Positive Breast Cancer to Bicalutamide: Case Report and Review of the Literature
- Case Report, BC, NA
Dose↝, Remission↑,
144- CUR,  Bical,    Combination of curcumin and bicalutamide enhanced the growth inhibition of androgen-independent prostate cancer cells through SAPK/JNK and MEK/ERK1/2-mediated targeting NF-κB/p65 and MUC1-C
- in-vitro, Pca, PC3 - in-vitro, NA, DU145 - in-vitro, NA, LNCaP
p‑ERK↑, p‑JNK↓, MUC1↓, p65↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

p‑JNK↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

p‑ERK↑, 1,  

Migration ⓘ

MUC1↓, 1,  

Immune & Inflammatory Signaling ⓘ

p65↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 1,  

Functional Outcomes ⓘ

Remission↑, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:186  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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