Database Query Results : nelfinavir/Viracept, ,

NRF, nelfinavir/Viracept: Click to Expand ⟱
Features:
NRF is an antiretroviral medication used in the treatment of HIV/AIDS.
Nelfinavir belongs to the class of drugs known as protease inhibitors and like other PIs is almost always used in combination with other antiretroviral drugs.
Scientific Papers found: Click to Expand⟱
150- NRF,  CUR,  docx,    Subverting ER-Stress towards Apoptosis by Nelfinavir and Curcumin Coexposure Augments Docetaxel Efficacy in Castration Resistant Prostate Cancer Cells
- in-vitro, Pca, C4-2B
p‑Akt↓, p‑eIF2α↑, ER Stress↑, ATFs↑, CHOP↑, TRIB3↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

p‑Akt↓, 1,  

Protein Folding & ER Stress ⓘ

ATFs↑, 1,   CHOP↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 1,  

Migration ⓘ

TRIB3↑, 1,  

Clinical Biomarkers ⓘ

TRIB3↑, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:187  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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