Database Query Results : beta-carotene(VitA), ,

betaCar, beta-carotene(VitA): Click to Expand ⟱
Features:
Beta carotene is a red-orange pigment found in plants and fruits, especially carrots and colorful vegetables. The body converts beta carotene into vitamin A.
-foods richest in carotenoids include carrots, sweet potatoes, pumpkin, spinach, cantaloupe, apricots and mangoes.
Beta carotene is a carotenoid and an antioxidant.
beta-carotene is known to have pro-oxidant activity in vitro
Beta carotene, a precursor of vitamin A and a well-known antioxidant, has been investigated for its potential roles in cancer prevention and therapy.

-By mitigating oxidative stress, beta carotene may indirectly reduce NF-κB activation.
-As a lipid-soluble molecule, beta carotene is integrated into cellular membranes, where it helps maintain membrane integrity and fluidity.
-at high concentrations or in the presence of high oxygen tension), beta carotene can exhibit pro-oxidant behavior, which may contribute to cellular damage.
Scientific Papers found: Click to Expand⟱
1566- betaCar,  Lyco,    Antioxidant and pro-oxidant effects of lycopene in comparison with beta-carotene on oxidant-induced damage in Hs68 cells
- in-vitro, Nor, HS68
*ROS↑, *ROS⇅, *Dose?,
3986- betaCar,  VitC,    Editorial: Impact of Diet on Learning, Memory and Cognition
- Review, AD, NA
*Risk↓, *neuroP↑,
3987- betaCar,  Lyco,    Carotenoid bioavailability is higher from salads ingested with full-fat than with fat-reduced salad dressings as measured with electrochemical detection
- Trial, AD, NA
*eff↑,
3988- betaCar,  Lut,  Zeax,    Effects of egg consumption on carotenoid absorption from co-consumed, raw vegetables
- Trial, AD, NA
*eff↑, *eff↑, *eff↑,
3989- betaCar,    Dietary factors that affect the bioavailability of carotenoids
*BioAv↑, *BioAv↑,
4061- betaCar,  VitB12,  VitB6,  FA,  VitB3  Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease
- Review, AD, NA
*cognitive↑, *cognitive↑, *Inflam↓, *homoC↓, *TNF-α↓, *other↝, *memory↑,
4078- betaCar,  VitC,  VitB6,    Impact of Diet on Learning, Memory and Cognition
- Review, AD, NA
*neuroP↑, *antiOx↑, *cognitive↑,
4080- betaCar,    Vitamin A and Alzheimer's disease
- Review, AD, NA
*antiOx↑, *cognitive↑, *Aβ↓,
4081- betaCar,    Vitamin A supplementation and risk of skeletal fracture
- Study, NA, NA
BMD↓,
4082- betaCar,    Marginal vitamin A deficiency facilitates Alzheimer's pathogenesis
- Study, AD, NA
*cognitive↑, *BACE↓, *memory↑,
4083- betaCar,    Significance of vitamin A to brain function, behavior and learning
- Review, AD, NA
*cognitive↑, *memory?,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 11

Pathway results for Effect on Cancer / Diseased Cells:


Clinical Biomarkers ⓘ

BMD↓, 1,  
Total Targets: 1

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   ROS↑, 1,   ROS⇅, 1,  

Core Metabolism/Glycolysis ⓘ

homoC↓, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,   TNF-α↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,   BACE↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 2,   Dose?, 1,   eff↑, 4,  

Functional Outcomes ⓘ

cognitive↑, 6,   memory?, 1,   memory↑, 2,   neuroP↑, 2,   Risk↓, 1,  
Total Targets: 17

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:194  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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