Database Query Results : Resiquimod, ,
RSQ, Resiquimod: Click to Expand ⟱
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Resiquimod is a synthetic compound that acts as an immune response modifier. It is a toll-like receptor 7 and 8 (TLR7/8) agonist, which means it activates these receptors on immune cells, such as dendritic cells and macrophages.
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Scientific Papers found: Click to Expand⟱
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in-vivo, |
Melanoma, |
SK-MEL-28 |
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in-vivo, |
Melanoma, |
WM35 |
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ROS↑, Ca+2↝, Casp3↑, Casp8↑, Casp9↑, CD4+↑, CD8+↑, tumCV↓, eff↓, *toxicity↓,
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 1,
Cell Death ⓘ
Casp3↑, 1, Casp8↑, 1, Casp9↑, 1,
Transcription & Epigenetics ⓘ
tumCV↓, 1,
Migration ⓘ
Ca+2↝, 1,
Immune & Inflammatory Signaling ⓘ
CD4+↑, 1,
Drug Metabolism & Resistance ⓘ
eff↓, 1,
Infection & Microbiome ⓘ
CD8+↑, 1,
Total Targets: 9
Pathway results for Effect on Normal Cells:
Functional Outcomes ⓘ
toxicity↓, 1,
Total Targets: 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:208 Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid
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