Database Query Results : Gossypol, ,

Gos, Gossypol: Click to Expand ⟱

Features:

Gossypol is a natural compound found in cottonseed, a byproduct of the cotton industry. It has been studied for its potential anti-cancer properties. Research has shown that gossypol can inhibit the growth of various types of cancer cells, including breast, prostate, lung, and colon cancer.

Gossypol's anti-cancer effects are thought to be due to its ability to:

-Inhibit the activity of certain enzymes involved in cancer cell growth and survival
-Induce apoptosis (cell death) in cancer cells
-Inhibit the formation of new blood vessels that feed cancer cells (anti-angiogenesis)
-Modulate the immune system to attack cancer cells

Some studies have also suggested that gossypol may have synergistic effects when combined with other anti-cancer agents, such as chemotherapy and radiation therapy.

Scientific Papers found: Click to Expand⟱

941-

Gos,

Rad,

The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis

in-vivo,

NA,

mice, injection to mice starting at week 4 postirradiation at a dose of 5 mg/kg in 30 μl volume

lactateProd↓, other↓, TGF-β↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Core Metabolism/Glycolysis ⓘ

lactateProd↓, 1,

Transcription & Epigenetics ⓘ

other↓, 1,

Migration ⓘ

TGF-β↓, 1,
Total Targets: 3

Pathway results for Effect on Normal Cells:

Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells