Database Query Results : Bruteridin, ,

Brut, Bruteridin: Click to Expand ⟱
Features:
Bruteridin is a lesser-known phytochemical that has been isolated from certain plant sources. Like other natural compounds with polyphenolic characteristics, bruteridin is of interest because of its potential antioxidant and anti-inflammatory activities. However, due to the limited body of research, its specific role as an anticancer agent remains largely underexplored.
Typically associated with natural cardenolide mixtures from specific cardenolide-producing plants (e.g., species in the Digitalis or Adonis genera) and possibly from amphibian secretions.

-Antioxidant Activity
-Anti-inflammatory Effects
-Changes in histone acetylation status and chromatin remodeling can lead to altered gene expression profiles that favor tumor suppression.
-Na+/K+-ATPase Inhibition
-interfere with the PI3K/Akt/mTOR signaling cascade
-linked to the generation of ROS within cells
-Cell Cycle Arrest
-Inhibition of NF-κB Signaling
-alter the MAPK/ERK signaling cascade
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:270  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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