Database Query Results : Purpurone, ,

Purp, Purpurone: Click to Expand ⟱
Features:
Purpurone is a natural product. Many reports indicate that it belongs to a family of naphthoquinone derivatives.

Pathways:
Induction of Apoptosis (Intrinsic/Mitochondrial Pathway):
– affecting MMP, leading to the release of cytochrome c and activation of downstream caspases.
Inhibition of NF-κB Signaling:
Cell Cycle Arrest: (often at the G2/M phase).
Induction of Oxidative Stress (ROS Generation):
Anti-Angiogenic Effects: inhibiting angiogenesis
ACLY inhibitor: IC50 = 7 uM


Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:279  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page