Database Query Results : Methyl Jasmonate, ,

MeJa, Methyl Jasmonate: Click to Expand ⟱
Features:
Methyl jasmonate (MeJa) is a well-known plant stress hormone.
Pathways:
-Causes mitochondrial dysfunction by inducing the release of cytochrome c, which leads to caspase activation.
- ↓ glycolysis via hexokinase-VDAC disruption
- ↑ ROS in cancer cells
-MJ can lead to cell cycle arrest, thereby inhibiting the proliferation of cancer cells
Scientific Papers found: Click to Expand⟱
1898- MeJa,    Methyl jasmonate and its potential in cancer therapy
- Review, Var, NA
ROS↑, selectivity↑, toxicity↝,
1899- MeJa,    Methyl jasmonate induces production of reactive oxygen species and alterations in mitochondrial dynamics that precede photosynthetic dysfunction and subsequent cell death
- in-vitro, NA, NA
ROS↑, MMP↓, eff↓, H2O2?,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

H2O2?, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↓, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

toxicity↝, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:294  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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