Database Query Results : Worenine, ,

Wor, Worenine: Click to Expand ⟱
Features:
Worenine - Coptis Chinensis (Huanglian in Chinese), a famous traditional herbal medicine used for clearing heat and detoxification.
Worenine is classified as a plant-derived alkaloid.

-Worenine may exert anti-inflammatory and antioxidant effects.
-Production of lactic acid and the uptake and consumption of glucose is significantly inhibited.
-The protein and mRNA levels of GLUT3, HK2, PFK-L, PKM2, and LDHA in HCT116 cells are reduced.
Scientific Papers found: Click to Expand⟱
2397- Wor,    Phytochemicals targeting glycolysis in colorectal cancer therapy: effects and mechanisms of action
- Review, Var, NA
lactateProd↓, GlucoseCon↓, GLUT3↓, HK2↓, PKM2↓, LDHA↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

GlucoseCon↓, 1,   HK2↓, 1,   lactateProd↓, 1,   LDHA↓, 1,   PKM2↓, 1,  

Barriers & Transport ⓘ

GLUT3↓, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:318  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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