Database Query Results : Mushroom Lion’s Mane, ,

mushLions, Mushroom Lion’s Mane: Click to Expand ⟱
Features:
Lion’s Mane Mushroom (Hericium erinaceus) is renowned for its potential health benefits, particularly in areas like neuroprotection, cognitive function, and immune support.

-Most commonly cited mechanisms of Lion’s Mane is its ability to stimulate the synthesis of Nerve Growth Factor (NGF)
-Specific compounds such as hericenones and erinacines present in the mushroom are thought to be responsible for this effect.
-May inhibit NF-κB Pathway
-May lower the production of pro-inflammatory cytokines (e.g., TNF-α, IL-6)
-Neutralize free radicals, reducing oxidative stress
-Lion’s Mane influences gut health and, in turn, the gut-brain axis
-Anti-inflammatory responses, antioxidant protection

-Mushrooms, including Lion’s Mane (Hericium erinaceus), contain ergosterol—a precursor to vitamin D. When exposed to ultraviolet (UV) light (such as sunlight), ergosterol is converted to vitamin D₂ (ergocalciferol).
Scientific Papers found: Click to Expand⟱
2484- mushLions,    Neurotrophic and Neuroprotective Effects of Hericium erinaceus
- Review, Stroke, NA - Review, AD, NA - Review, Park, NA
*eff↑, *BBB↑, *Dose↝, *neuroP↑, *cognitive↑, *toxicity∅,
3806- mushLions,    Dietary Supplementation of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), and Spatial Memory in Wild-Type Mice
- in-vitro, NA, NA
*motorD↑, *memory↑,
3807- mushLions,    Searching for a Longevity Food, We Bump into Hericium erinaceus Primordium Rich in Ergothioneine: The “Longevity Vitamin” Improves Locomotor Performances during Aging
*AntiAge↑, *other↑, *NOS2↓, *COX2↓, *P53↑, *neuroP↑,
3808- mushLions,    Neuroprotective Metabolites of Hericium erinaceus Promote Neuro-Healthy Aging
- in-vitro, NA, NA
*Inflam↓, *ROS↓, *neuroP↑,
3809- mushLions,    The Monkey Head Mushroom and Memory Enhancement in Alzheimer's Disease
- Review, NA, NA
*cognitive↑, *Apoptosis↓, *Aβ↓, *AChE↓, *BACE↓,
3810- mushLions,    Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer’s Disease
- Review, NA, NA
*neuroP↑, *p‑tau↓, *APP↓, *Aβ↓, *ROS↓, *Inflam↓, *NLRP3↓,
3811- mushLions,    Hericium erinaceus (Bull.) Pers. Ethanolic Extract with Antioxidant Properties on Scopolamine-Induced Memory Deficits in a Zebrafish Model of Cognitive Impairment
- in-vitro, NA, NA
*memory↑, *BBB↑, *GSH↑, *AChE↓, *MDA↓,
3812- mushLions,    Structural characterization of polysaccharide purified from Hericium erinaceus fermented mycelium and its pharmacological basis for application in Alzheimer's disease: Oxidative stress related calcium homeostasis
- in-vitro, AD, NA
*cognitive↑, *Aβ↓, *p‑tau↓, *ROS↓, *NRF2↓, *Ca+2↝,
3813- mushLions,    Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice
- in-vitro, AD, NA
*Aβ↓, *cognitive↑, *neuroP↑,
3814- mushLions,    Lion's Mane (Hericium erinaceus) Exerts Anxiolytic Effects in the rTg4510 Tau Mouse Model
- in-vitro, AD, NA
*neuroP↑, *cognitive↑, *cognitive∅, *BBB↑, *NGF↑, *BDNF↑, *NO↓, *memory↑, *Aβ↓,
3815- mushLions,    Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines
- Review, Stroke, NA - Review, Park, NA - Review, AD, NA
*eff↑, *cognitive↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 11

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

GSH↑, 1,   MDA↓, 1,   NRF2↓, 1,   ROS↓, 3,  

Cell Death ⓘ

Apoptosis↓, 1,  

Transcription & Epigenetics ⓘ

other↑, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Migration ⓘ

APP↓, 1,   Ca+2↝, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Barriers & Transport ⓘ

BBB↑, 3,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   Inflam↓, 2,  

Synaptic & Neurotransmission ⓘ

AChE↓, 2,   BDNF↑, 1,   NGF↑, 1,   p‑tau↓, 2,  

Protein Aggregation ⓘ

Aβ↓, 5,   BACE↓, 1,   NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 1,   eff↑, 2,  

Clinical Biomarkers ⓘ

NOS2↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 1,   cognitive↑, 6,   cognitive∅, 1,   memory↑, 3,   motorD↑, 1,   neuroP↑, 6,   toxicity∅, 1,  
Total Targets: 30

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:325  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page