Database Query Results : MCToil, ,

MCT, MCToil: Click to Expand ⟱
Features:
MCT oils typically consist of medium-chain fatty acids such as caprylic acid (C8) and capric acid (C10). Here are some examples and sources of MCT oils:
• Purified MCT Oil Products:
– Commercial MCT oils (e.g., Nature’s Way MCT Oil, Now Sports MCT Oil) are available as dietary supplements and are often used in both nutritional and pharmaceutical applications.
– These products are refined to contain mostly C8 and C10 fatty acids, which are known for their rapid digestion and absorption.
• Coconut Oil (Fractionated):
– Although traditional coconut oil contains a mix of medium-chain (and longer-chain) fatty acids, fractionated coconut oil has been processed to separate the medium-chain triglycerides (mainly C8 and C10).
– This fractionated form is liquid at room temperature and can serve a similar purpose as purified MCT oil in formulations.
- MCT oil is rapidly metabolized in the liver to produce ketone bodies, making it a common component of ketogenic diets.


Scientific Papers found: Click to Expand⟱
2642- Flav,  QC,  Api,  KaempF,  MCT  In Vitro–In Vivo Study of the Impact of Excipient Emulsions on the Bioavailability and Antioxidant Activity of Flavonoids: Influence of the Carrier Oil Type
- in-vitro, Nor, NA - in-vivo, Nor, NA
*BioAv↑, *eff↝, BioEnh↑,
2643- MCT,    Medium Chain Triglycerides enhances exercise endurance through the increased mitochondrial biogenesis and metabolism
- Review, Nor, NA
*Akt↑, *AMPK↓, *TGF-β↓, eff↑, *BioEnh↑, *ATP↑, *PGC-1α↑, *p‑mTOR↑, *SMAD3↓,
2644- MCT,    The Effects of Medium-Chain Triglyceride Oil Supplementation on Endurance Performance and Substrate Utilization in Healthy Populations: A Systematic Review
- Review, Nor, NA
*KeyT↑, *Dose↝, eff↑,
3895- MCT,    How does coconut oil affect cognitive performance in alzheimer patients?
- Human, AD, NA
*cognitive↑,
3896- MCT,    Improvement of Main Cognitive Functions in Patients with Alzheimer's Disease after Treatment with Coconut Oil Enriched Mediterranean Diet: A Pilot Study
- Trial, AD, NA
*memory↑, *cognitive↑,
3897- MCT,    The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells
- in-vitro, AD, NA
*ROS↓, *H2O2↓,
3898- MCT,    Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer's disease
- Review, AD, NA
*neuroP↑, *cognitive↑, *Aβ↓, *Inflam↓, *ROS↓,
3899- MCT,    COCONUT OIL: NON-ALTERNATIVE DRUG TREATMENT AGAINST ALZHEIMER´S DISEASE
- Human, AD, NA
*cognitive?,
3900- MCT,    Coconut (Cocos nucifera) Ethanolic Leaf Extract Reduces Amyloid-β (1-42) Aggregation and Paralysis Prevalence in Transgenic Caenorhabditis elegans Independently of Free Radical Scavenging and Acetylcholinesterase Inhibition
- in-vitro, AD, NA
*ROS↑, *AChE↓, *Aβ↓,
3901- MCT,    Potential of Capric Acid in Neurological Disorders: An Overview
- Review, AD, NA
*BBB↑, *cognitive↑,
3902- MCT,    Effects of Caprylic Triglyceride on Cognitive Performance and Cerebral Glucose Metabolism in Mild Alzheimer’s Disease: A Single-Case Observation
- Case Report, AD, NA
*cognitive↑, *KeyT↑,
3903- MCT,    Retrospective case studies of the efficacy of caprylic triglyceride in mild-to-moderate Alzheimer’s disease
- Case Report, AD, NA
*KeyT↑, *cognitive↑, *eff↑,
3904- MCT,    Retrospective cohort study of the efficacy of caprylic triglyceride in patients with mild-to-moderate alzheimer’s disease
- Human, AD, NA
*memory↑, *cognitive↑, *KeyT↑,
3905- MCT,    Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer's disease. A systematic review and meta-analysis of human studies
- Review, AD, NA
*cognitive↑, *KeyT↑, *eff↑, *other↑, *toxicity↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 14

Pathway results for Effect on Cancer / Diseased Cells:


Drug Metabolism & Resistance

BioEnh↑, 1,   eff↑, 2,  
Total Targets: 2

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

H2O2↓, 1,   ROS↓, 2,   ROS↑, 1,  

Mitochondria & Bioenergetics

ATP↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis

AMPK↓, 1,   KeyT↑, 5,  

Cell Death

Akt↑, 1,  

Transcription & Epigenetics

other↑, 1,  

Proliferation, Differentiation & Cell State

p‑mTOR↑, 1,  

Migration

SMAD3↓, 1,   TGF-β↓, 1,  

Barriers & Transport

BBB↑, 1,  

Immune & Inflammatory Signaling

Inflam↓, 1,  

Synaptic & Neurotransmission

AChE↓, 1,  

Protein Aggregation

Aβ↓, 2,  

Drug Metabolism & Resistance

BioAv↑, 1,   BioEnh↑, 1,   Dose↝, 1,   eff↑, 2,   eff↝, 1,  

Functional Outcomes

cognitive?, 1,   cognitive↑, 8,   memory↑, 2,   neuroP↑, 1,   toxicity↓, 1,  
Total Targets: 26

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:333  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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