Database Query Results : Phosphatidylserine, ,

PS, Phosphatidylserine: Click to Expand ⟱
Features:
PS is a negatively charged phospholipid found predominantly in the inner leaflet of cell membranes, especially in neurons.
-Clinical trials show potential benefits in:
-Improving memory and attention in elderly subjects
-Slowing cognitive decline in early AD or mild cognitive impairment (MCI)
-PS is thought to enhance cell membrane function, neurotransmission, and possibly reduce oxidative stress.
Scientific Papers found: Click to Expand⟱
3715- FA,  CUR,  PS,    The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice
- in-vivo, AD, NA
*cognitive↑, *IL1β↓, *Ach↑, *Aβ↓, *p‑tau↓, *BDNF↑, *APP↓,
3906- PS,    Effects of phosphatidylserine in Alzheimer's disease
- Study, AD, NA
*cognitive↑,
3907- PS,    Long-term effects of phosphatidylserine, pyritinol, and cognitive training in Alzheimer's disease. A neuropsychological, EEG, and PET investigation
- Study, AD, NA
*cognitive↝,
3908- PS,    The effect of phosphatidylserine-containing omega-3 fatty acids on memory abilities in subjects with subjective memory complaints: a pilot study
- Human, AD, NA
*cognitive↑, *memory↑,
3909- PS,    Double-blind study with phosphatidylserine (PS) in parkinsonian patients with senile dementia of Alzheimer's type (SDAT)
- Study, AD, NA
*cognitive↑,
3910- PS,    Neuroprotective Effect of Bean Phosphatidylserine on TMT-Induced Memory Deficits in a Rat Model
- in-vivo, AD, NA
*memory↑, *neuroP↑, *GlucoseCon↑, *ChAT↑,
3911- PS,  VitE,    Cognitive effects of a dietary supplement made from extract of Bacopa monnieri, astaxanthin, phosphatidylserine, and vitamin E in subjects with mild cognitive impairment: a noncomparative, exploratory clinical study
- Human, AD, NA
*cognitive↑, *other↑,
3912- PS,    Cognitive decline in the elderly: a double-blind, placebo-controlled multicenter study on efficacy of phosphatidylserine administration
- Study, AD, NA
cognitive↑,
3913- PS,    An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline
- Human, AD, NA
*cognitive↑,
3914- PS,    Soybean-Derived Phosphatidylserine Improves Memory Function of the Elderly Japanese Subjects with Memory Complaints
- Trial, AD, NA
*memory↑, *cognitive↑, *lipid-P↓, *antiOx↑, *Inflam↓,
3915- PS,    Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with Alzheimer's disease and dementia
- Trial, AD, NA
*memory↑, *cognitive↑, *Half-Life↝, *Mood↑,
3916- PS,    The effect of soybean-derived phosphatidylserine on cognitive performance in elderly with subjective memory complaints: a pilot study
- Human, AD, NA
*memory↑, *cognitive↑, *BP↓, *Dose↝, *eff↑,
3917- PS,    Phosphatidylserine, inflammation, and central nervous system diseases
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *neuroP↑, *cognitive↑, *Choline↑, *IL1β↓, *IL6↓, *TNF-α↓, *Ach↑, *eff↑, *eff↑, *BioEnh↑, other↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 13

Pathway results for Effect on Cancer / Diseased Cells:


Transcription & Epigenetics ⓘ

other↑, 1,  

Functional Outcomes ⓘ

cognitive↑, 1,  
Total Targets: 2

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   lipid-P↓, 1,  

Core Metabolism/Glycolysis ⓘ

GlucoseCon↑, 1,  

Transcription & Epigenetics ⓘ

Ach↑, 2,   other↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

Choline↑, 1,  

Migration ⓘ

APP↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 2,   IL6↓, 1,   Inflam↓, 2,   TNF-α↓, 1,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,   ChAT↑, 1,   p‑tau↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,  

Drug Metabolism & Resistance ⓘ

BioEnh↑, 1,   Dose↝, 1,   eff↑, 3,   Half-Life↝, 1,  

Clinical Biomarkers ⓘ

BP↓, 1,   IL6↓, 1,  

Functional Outcomes ⓘ

cognitive↑, 10,   cognitive↝, 1,   memory↑, 5,   Mood↑, 1,   neuroP↑, 2,  
Total Targets: 26

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:341  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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