Database Query Results : Carnosine, ,

Carno, Carnosine: Click to Expand ⟱
Features:
L-Carnosine (usually just called "Carnosine") is a naturally occurring dipeptide composed of L-histidine and β-alanine, found in high concentrations in muscle and brain tissue.
-Source: only found in animals Beef(372mg/100g), ChickenBreast(290mg/100g), Pork(276mg/100g), TurkeyBreast(240mg/100g)
-Anserine is a derivative of carnosine
-Scavenges reactive oxygen species (ROS)
-Inhibits formation of AGEs (advanced glycation end-products), which are linked to aging and neurodegeneration.
-Metal chelator: Binds excess zinc, copper, and iron—important in brain health.
Scientific Papers found: Click to Expand⟱
3869- Carno,    Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *IronCh↑, *AntiAge↑, *antiOx↑, *Inflam↓, *neuroP↑, *lipid-P↓, *toxicity↓, *NOX4↓, *SOD↑, *HNE↓, *IL6↓, *TNF-α↓, *IL1β↓, *Sepsis↓, *eff↑, *GABA↝, *Aβ↓, Glycolysis↓, AntiTum↑, p‑Akt↓, TumCCA↑, angioG↓, VEGFR2↓, NF-kB↓,
3870- Carno,    Could carnosine or related structures suppress Alzheimer's disease?
- Review, AD, NA
*IronCh↑, *Aβ↓, *ROS↓, *Vim↓,
3871- Carno,    Unveiling the Hidden Therapeutic Potential of Carnosine, a Molecule with a Multimodal Mechanism of Action: A Position Paper
- Review, NA, NA
*ROS↓, *NO↓, *Inflam↓,
3872- Carno,    Carnosine Protects Macrophages against the Toxicity of Aβ1-42 Oligomers by Decreasing Oxidative Stress
- in-vitro, AD, NA
*antiOx↑, *Inflam↓, *Aβ↓, *neuroP↑, *ROS↓, *NO↓,
3873- Carno,    Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice
- in-vivo, AD, NA
*ROS↓, *IronCh↑, *Aβ↓, *AntiAge↑, *lipid-P↓, *cognitive↑, *memory∅,
3874- Carno,    Effects of zinc and carnosine on aggregation kinetics of Amyloid-β40 peptide
- Review, AD, NA
*Aβ↓, *IronCh↑,
3875- Carno,    Ionophore Ability of Carnosine and Its Trehalose Conjugate Assists Copper Signal in Triggering Brain-Derived Neurotrophic Factor and Vascular Endothelial Growth Factor Activation In Vitro
- in-vitro, AD, NA
*IronCh↑, *CREB↑, *BDNF↑, *NGF↑, *antiOx↑, *ROS↓,
3876- Carno,  Ex,    Swimming exercise versus L-carnosine supplementation for Alzheimer’s dementia in rats: implication of circulating and hippocampal FNDC5/irisin
- in-vivo, AD, NA
*cognitive↑, *neuroP↑,
3877- Carno,    Carnosine, diabetes and Alzheimer's disease
- Review, AD, NA
*toxicity∅, *antiOx↑, IronCh↑,
3878- Carno,    Safety and Efficacy Evaluation of Carnosine, An Endogenous Neuroprotective Agent for Ischemic Stroke
- in-vivo, Stroke, NA
*toxicity∅, *antiOx↑, *neuroP↑, *IronCh↑, *ROS↓,
3879- Carno,    Daily Carnosine and Anserine Supplementation Alters Verbal Episodic Memory and Resting State Network Connectivity in Healthy Elderly Adults
- Human, AD, NA
*memory↑, *cognitive↑,
3880- Carno,    EFFECT OF ANSERINE/CARNOSINE SUPPLEMENTATION ON THE PREVENTION OF ALZHEIMER'S DISEASE IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT
- Trial, AD, NA
*cognitive↑, *other↑,
3881- Carno,    The Therapeutic Potential of Carnosine/Anserine Supplementation against Cognitive Decline: A Systematic Review with Meta-Analysis
- Review, AD, NA
*cognitive↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 13

Pathway results for Effect on Cancer / Diseased Cells:


Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis ⓘ

Glycolysis↓, 1,  

Cell Death ⓘ

p‑Akt↓, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   VEGFR2↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  

Functional Outcomes ⓘ

AntiTum↑, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 5,   HNE↓, 1,   lipid-P↓, 2,   NOX4↓, 1,   ROS↓, 7,   SOD↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 6,  

Core Metabolism/Glycolysis ⓘ

CREB↑, 1,  

Transcription & Epigenetics ⓘ

other↑, 1,  

Migration ⓘ

Vim↓, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 2,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 1,   IL6↓, 1,   Inflam↓, 3,   TNF-α↓, 1,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,   GABA↝, 1,   NGF↑, 1,  

Protein Aggregation ⓘ

Aβ↓, 5,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 2,   cognitive↑, 5,   memory↑, 1,   memory∅, 1,   neuroP↑, 4,   toxicity↓, 1,   toxicity∅, 2,  

Infection & Microbiome ⓘ

Sepsis↓, 1,  
Total Targets: 29

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:351  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page