Database Query Results : Serotonin, 5-hydroxytryptamine, ,

5HT, Serotonin, 5-hydroxytryptamine: Click to Expand ⟱
Features:
5-HT (5-hydroxytryptamine), commonly known as serotonin, plays a significant role in Alzheimer’s disease (AD). Its dysfunction is associated with both the cognitive and neuropsychiatric symptoms of AD.
-Serotonin is a neurotransmitter involved in: Mood regulation, Sleep, Cognition, Appetite
-Decreased serotonin levels are seen in the brains of AD patients.
-Serotonin may reduce Aβ production via certain receptor pathways (e.g., 5-HT4 activation).
Natural Serotonin Enhancers
-5-HTP	                        Direct precursor to serotonin
-Curcumin	                MAO-A inhibitor (prevent serotonin breakdown)
-Resveratrol	                Inhibits MAO (prevent serotonin breakdown)
-Tryptophan	                Amino acid precursor to serotonin
-Saffron (crocin)	        Inhibits serotonin reuptake	↑ Synaptic 5-HT
-Green tea (L-theanine)
-Ginkgo biloba
-Omega-3 fatty acids	        Enhances serotonin release 
-Vitamin B6, B12, Folate	Cofactors in serotonin synthesis


Scientific Papers found: Click to Expand⟱
3940- 5HT,    Role of serotonin in Alzheimer's disease: a new therapeutic target?
- Review, AD, NA
*cognitive↑,
3941- 5HT,  dietMed,  VitB12,  FA,  VitC  Nutrition strategies that improve cognitive function
- Review, AD, NA
*other↑, *other↓, *cognitive↑, *eff↑, *eff↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Transcription & Epigenetics ⓘ

other↓, 1,   other↑, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 2,  

Functional Outcomes ⓘ

cognitive↑, 2,  
Total Targets: 4

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:353  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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