Database Query Results : Silicic Acid, ,

Silicon, Silicic Acid: Click to Expand ⟱
Features:
Silicon and its derivatives—especially silicic acid—have been studied for potential neuroprotective effects, including in the context of Alzheimer’s disease (AD).
-Silicon is a trace element involved in bone health, connective tissue, and possibly cognitive function.
-It is most bioavailable in the form of orthosilicic acid (OSA), a soluble and absorbable form often found in drinking water or supplements
-Silicon binds aluminum, forming hydroxyaluminosilicates that are poorly absorbed by the gut and are more easily excreted.
-Silicic acid may protect neurons from oxidative and inflammatory stress, mechanisms relevant to AD.
Scientific Papers found: Click to Expand⟱
4122- Silicon,    Silicon-rich mineral water as a non-invasive test of the 'aluminum hypothesis' in Alzheimer's disease
- Trial, AD, NA
*other↓, *other∅, *cognitive↑,
4123- Silicon,    The potential influence of silica present in drinking water on Alzheimer's disease and associated disorders
- Review, AD, NA
*Aβ↓, *cognitive↝,
4125- Silicon,    Oral silicon supplementation: an effective therapy for preventing oral aluminum absorption and retention in mammals
- Review, AD, NA
*neuroP↑, *BioAv↓,
4126- Silicon,  H2,    Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method
- in-vivo, NA, NA
*creat↓, *ROS↓, *other↑, *MDA↓, *other↑, *Inflam↓,
4127- Silicon,    Interference of Parenteral Nutrition Components in Silicon-Mediated Protection Against Aluminum Bioaccumulation
- in-vivo, AD, NA
*other↓, *neuroP↑,
4128- Silicon,    Silicon as Versatile Player in Plant and Human Biology: Overlooked and Poorly Understood
- Review, NA, NA
*other↑, *BMD↑, *Dose↝, *cognitive↑, *Dose?,
4129- Silicon,    Silica and aluminum in drinking water and cognitive impairment in the elderly
- Study, AD, NA
*cognitive↑,
4131- Silicon,    Silicon reduces aluminum accumulation in rats: relevance to the aluminum hypothesis of Alzheimer disease
- Study, Nor, NA
*other↓, *BioAv↓, *neuroP↑,
4133- Silicon,    Relation between aluminum concentrations in drinking water and Alzheimer's disease: an 8-year follow-up study
- Study, AD, NA
*Risk↓, *Dose↑, *neuroP↑,
4134- Silicon,    Garden Cress (Lepidium sativum) Seeds Ameliorated Aluminum-Induced Alzheimer Disease in Rats Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Effects
- in-vivo, AD, NA
*neuroP↑, *BioAv↓, *cognitive↑,
4136- Silicon,    Aluminum Should Now Be Considered a Primary Etiological Factor in Alzheimer’s Disease
- Review, AD, NA
*cognitive↑, *Risk↓, *neuroP↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 11

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

MDA↓, 1,   ROS↓, 1,  

Transcription & Epigenetics ⓘ

other↓, 3,   other↑, 3,   other∅, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 3,   Dose?, 1,   Dose↑, 1,   Dose↝, 1,  

Clinical Biomarkers ⓘ

BMD↑, 1,   creat↓, 1,  

Functional Outcomes ⓘ

cognitive↑, 5,   cognitive↝, 1,   neuroP↑, 6,   Risk↓, 2,  
Total Targets: 17

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:362  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page