Database Query Results : Anzaroot, Astragalus fasciculifolius Bioss, ,

Anzaroot, Anzaroot, Astragalus fasciculifolius Bioss: Click to Expand ⟱
Features:
Anzaroot, Astragalus fasciculifolius Bioss : (the traditional gum/resin from Astragalus sarcocolla, also written “sarcocolla” or “sarcocolla gum”) is a complex natural product whose main bioactive classes are — polysaccharides (gum carbohydrates), flavonoids/phenolics, and triterpene saponins (including astragaloside-type saponins in the broader Astragalus genus
-extracts or Anzaroot-mediated silver nanoparticles have shown cytotoxic effects on cancer cell lines; the proposed anticancer mechanisms are apoptosis induction, ROS generation, cell-cycle arrest and immunomodulation via NF-κB / PI3K-Akt / MAPK and caspase pathways.
Scientific Papers found: Click to Expand⟱
4413- SNP,  Anzaroot,    Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cells
- in-vitro, BC, MCF-7
chemoP↑, TumCG↓, eff↑, CellMemb↑, selectivity↑, ROS↑, P53↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,  

Barriers & Transport ⓘ

CellMemb↑, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

chemoP↑, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:370  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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