Database Query Results : Carvacrol, ,

CAR, Carvacrol: Click to Expand ⟱
Features:
Carvacrol monoterpenoid phenol with odor of oregano. Found in essential oils and plants, has antimicorbial and antioxidant properties.
Scientific Papers found: Click to Expand⟱
1082- CAR,    Carvacrol, a component of thyme oil, activates PPARα and γ and suppresses COX-2 expression
- in-vitro, lymphoma, U937
COX2↓, PPARα↑, PPARγ↑,
1104- CAR,    Carvacrol Ameliorates Transforming Growth Factor-β1-Induced Extracellular Matrix Deposition and Reduces Epithelial-Mesenchymal Transition by Regulating The Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway In Hk-2 Cells
- in-vitro, Kidney, HK-2
tumCV↓, COL4↓, COL1↓, Fibronectin↓, E-cadherin↑, Snail↑, Vim↑, α-SMA↑, PI3K↓, Akt↓,
1287- CAR,    Carvacrol induces apoptosis in human breast cancer cells via Bcl-2/CytC signaling pathway
- in-vitro, BC, HCC1937
TumCP↓, TumCCA↑, Apoptosis↑, BAX↑, Cyt‑c↑, Casp3↑, Bcl-2↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

PPARα↑, 1,   PPARγ↑, 1,  

Cell Death ⓘ

Akt↓, 1,   Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,   Cyt‑c↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

PI3K↓, 1,  

Migration ⓘ

COL1↓, 1,   COL4↓, 1,   E-cadherin↑, 1,   Fibronectin↓, 1,   Snail↑, 1,   TumCP↓, 1,   Vim↑, 1,   α-SMA↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,  
Total Targets: 20

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:57  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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