Database Query Results : bempedoic acid, ,

bemp, bempedoic acid: Click to Expand ⟱
Features:
Bempedoic acid> is a synthetic small‐molecule drug developed to lower low‐density lipoprotein cholesterol (LDL-C) by targeting lipid metabolism in the liver. Its design and development were based on a detailed understanding of cholesterol biosynthetic pathways rather than on a natural product scaffold.

Key Pathways:
-ATP Citrate Lyase (ACLY) Inhibition
-Fatty Acid Synthesis and Lipogenesis
• With reduced acetyl-CoA, de novo fatty acid synthesis is also curtailed.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:63  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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