Database Query Results : Indole-3-carbinol, ,

I3C, Indole-3-carbinol: Click to Expand ⟱
Features:
Found in broccoli, cabbage, cauliflower, brussel sprouts, collard greens and kale.
Scientific Papers found: Click to Expand⟱
1277- I3C,  GEN,    Modulation of the constitutive activated STAT3 transcription factor in pancreatic cancer prevention: effects of indole-3-carbinol (I3C) and genistein
- in-vitro, PC, PANC1
STAT3↓, Apoptosis↑,
1278- I3C,    Indole-3-carbinol inhibits prostate cancer cell migration via degradation of beta-catenin
- in-vivo, Pca, DU145
TumCMig↓, β-catenin/ZEB1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Apoptosis↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

STAT3↓, 1,  

Migration ⓘ

TumCMig↓, 1,   β-catenin/ZEB1↓, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:99  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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