neuroP Cancer Research Results

neuroP, neuroprotective: Click to Expand ⟱
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Neuroprotective refers to the ability of a substance, intervention, or strategy to preserve the structure and function of nerve cells (neurons) against injury or degeneration.
-While cancer and neurodegenerative processes might seem distinct, there is significant overlap in terms of treatment-related neurotoxicity, shared molecular mechanisms, and the potential for therapies that provide neuroprotection during cancer treatment.


Scientific Papers found: Click to Expand⟱
3528- Lyco,    The Importance of Antioxidant Activity for the Health-Promoting Effect of Lycopene
- Review, Nor, NA - Review, AD, NA - Review, Park, NA
*antiOx↑, *ROS↓, *BioAv↝, *Half-Life↑, *BioAv↓, *BioAv↑, *cardioP↑, *neuroP↑, *H2O2↓, *VitC↑, *VitE↑, *GPx↑, *GSH↑, *MPO↓, *GSTs↓, *SOD↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL10↑, *MAPK↓, *Akt↓, *COX2/PTGS2↓, *TNF-α↓, *TGF-β1↑, *NO↓, *GSR↑, *NRF2↑, *HO-1↑, *TAC↑, *Inflam↓, *BBB↑, *neuroP↑, *memory↑,
3268- Lyco,    Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
- Review, AD, NA
*BioAv↓, *AntiCan↑, *ROCK1↓, *Ki-67↓, *ICAM-1↓, *cardioP↑, *antiOx↑, *NQO1↑, *HO-1↑, *TNF-α↓, *IL22↓, *NRF2↑, *NF-kB↓, *MDA↓, *Catalase↑, *SOD↑, *GSH↑, *cognitive↑, *tau↓, *hepatoP↑, *MMP2↑, *AST↓, *ALAT↓, *P450↑, *DNAdam↓, *ROS↓, *neuroP↑, *memory↑, *Ca+2↓, *Dose↝, *Dose↑, *Dose↝, *toxicity∅, PGE2↓, CDK2↓, CDK4↓, STAT3↓, NOX↓, NOX4↓, ROS↓, *SREBP1/SREBF1↓, *FASN↓, *ACC↓,
3264- Lyco,    Pharmacological potentials of lycopene against aging and aging‐related disorders: A review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *GSTs↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *iNOS↓, *NO↓, *TAC↑, *NOX4↓, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *IL1β↓, *TNF-α↓, *TLR2↓, *TLR4↓, *VCAM-1↓, *ICAM-1↓, *STAT3↓, *NF-kB↓, *ERK↓, *BP↓, ROS↓, PGE2↓, cardioP↑, *neuroP↑, *creat↓, *RenoP↑, *CRM↑,
1713- Lyco,    Lycopene: A Potent Antioxidant with Multiple Health Benefits
- Review, Nor, NA
*antiOx↑, *ROS⇅, *Dose↝, *eff↑, *LDL↓, *RenoP↑, *Inflam↓, neuroP↑, Rho↓,
4229- Lyco,    Implicating the role of lycopene in restoration of mitochondrial enzymes and BDNF levels in β-amyloid induced Alzheimer׳s disease
- in-vivo, AD, NA
*antiOx↑, *neuroP↑, *AntiCan↑, *memory↑, *ROS↓, *BDNF↑, *cognitive↑,
4228- Lyco,    A review for the pharmacological effect of lycopene in central nervous system disorders
- Review, AD, NA - Review, Park, NA
*cognitive↑, *memory↑, *Inflam↓, *Apoptosis↓, *ROS↓, *neuroP↑, *NF-kB↓, *JNK↓, *NRF2↑, *BDNF↑, *MDA↓, *GPx↑,
4780- Lyco,    Potential inhibitory effect of lycopene on prostate cancer
- Review, Pca, NA
TumCP↓, TumCCA↑, Apoptosis↑, *neuroP↑, *NF-kB↓, *JNK↓, *NRF2↑, *BDNF↑, *Ca+2↝, *antiOx↑, *AntiCan↑, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *TNF-α↓, NF-kB↓, DNAdam↓, PSA↓, P53↓, cycD1/CCND1↓, NRF2↓, Akt2↓, PPARγ↓,
4784- Lyco,    Protective effects of lycopene in cancer, cardiovascular, and neurodegenerative diseases: An update on epidemiological and mechanistic perspectives
- Review, Diabetic, NA - Review, CardioV, NA
*antiOx↑, *IL8↓, *IL6↓, *IL1↓, *NF-kB↓, Inflam↓, cycD1/CCND1↓, MMP2↓, MMP9↓, Bcl-2↓, NF-kB↓, *Nrf1↑, *antiOx↑, *BDNF↑, *neuroP↑, *cardioP↑, ROS↑, Dose↝,
4788- Lyco,    Lycopene as a potential anticancer agent: Current evidence on synergism, drug delivery systems and epidemiology (Review)
- Review, Var, NA
AntiCan↑, ChemoSen↑, chemoP↑, Dose↝, BioAv↑, BioAv↑, BioAv↓, cardioP↑, AntiDiabetic↑, hepatoP↑, neuroP↑, MAPK↓, MMP2↓, MMP9↓, TIMP1↑, TIMP2↑,
4789- Lyco,    Inhibitory Effect of Lycopene on Amyloid-β-Induced Apoptosis in Neuronal Cells
- in-vitro, AD, SH-SY5Y
*antiOx↑, *ROS↓, *NF-kB↓, *neuroP↑, *MMP↓, *mtDam↓, *OCR↓,
2545- M-Blu,    Reversing the Warburg Effect as a Treatment for Glioblastoma
- in-vitro, GBM, U87MG - NA, AD, NA - in-vitro, GBM, A172 - in-vitro, GBM, T98G
Warburg↓, OCR↑, lactateProd↓, TumCP↓, TumCCA↑, AMPK↑, ACC↓, Cyc↓, neuroP↑, Cyt‑c↝, Glycolysis↓, ECAR↓, TumCG↓, other↓,
2544- M-Blu,    Methylene blue and its importance in medicine
- Review, NA, NA
*ROS↓, antiOx↑, BBB↑, neuroP↑, GSR↓, tau↓,
2540- M-Blu,    Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots
- Review, Var, NA - Review, AD, NA
*OCR↑, *Glycolysis↓, *GlucoseCon↑, neuroP↑, Warburg↓, mt-OXPHOS↑, TumCCA↑, TumCP↓, ROS⇅, *cognitive↑, *mTOR↓, *mt-antiOx↑, *memory↑, *BBB↑, *eff↝, *ECAR↓, eff↑, lactateProd↓, NADPH↓, OXPHOS↑, AMPK↑, selectivity↑,
4528- MAG,    Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update
- Review, Nor, NA
*Inflam↑, *cardioP↑, *angioG↓, *antiOx↑, *neuroP↑, *Bacteria↓, AntiTum↑, TumCG↓, TumCMig↓, TumCI↓, Apoptosis↑, E-cadherin↑, NF-kB↓, TumCCA↑, cycD1/CCND1↓, PCNA↓, Ki-67↓, MMP2↓, MMP7↓, MMP9↓, TumCG↓, Casp3↑, NF-kB↓, Akt↓, mTOR↓, LDH↓, Ca+2↑, eff↑, *toxicity↓, *BioAv↝, *PGE2↓, *TLR2↓, *TLR4↓, *MAPK↓, *PPARγ↓,
4529- MAG,    Effectiveness of Magnolol, a Lignan from Magnolia Bark, in Diabetes, Its Complications and Comorbidities—A Review
- Review, Diabetic, NA
*AntiDiabetic↑, *glucose↓, *SOD↑, *Catalase↑, *ROS↓, *MDA↓, *GPx↑, *CYP2E1↓, *AGEs↓, *IL10↑, *neuroP↑, *GutMicro↑,
5252- MAG,    Insights on the Multifunctional Activities of Magnolol
- Review, Var, NA
BioAv↓, *Inflam↓, *Bacteria↓, *antiOx↑, *neuroP↑, *cardioP↑, CYP1A1↓, *PPARγ↑, *NF-kB↓, *COX2/PTGS2↓, *iNOS↓, *ROS↓, Apoptosis↑, TumCCA↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, P21↑, TumCG↓, TumCMig↓, TumCI↓, Ki-67↓, PCNA↓, MMP2↓, MMP9↓, MMP7↓, DNAdam↑, MMP↓, TumCP↓, selectivity↑, PI3K↓, Akt↓, H2O2↓, Hif1a↓, *BDNF↑, *NRF2↑, *AChE↑,
7824- MBS,  IVT,  VT,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA - Review, Stroke, NA - Review, Park, NA
*neuroP↑, *Aβ↓, *p‑tau↓, *ROS↓, *Inflam↓, *AChE↓, *BBB↑, *memory↑, *hepatoP↑, *Imm↑, *hyperG↓, *AntiCan↑, *eff↑, *Stroke↓, *BACE/β-secretase↓, *PI3K↓, *Akt↓, *mTOR↓, *Dose↓,
3898- MCT,    Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer's disease
- Review, AD, NA
*neuroP↑, *cognitive↑, *Aβ↓, *Inflam↓, *ROS↓,
1776- MEL,    Therapeutic strategies of melatonin in cancer patients: a systematic review and meta-analysis
- Review, NA, NA
Remission↑, OS↑, neuroP↑, VEGF↓, KISS1↑, TumCP↓, ChemoSideEff↓, radioP↑, Dose∅, *ROS↓, DNArepair↑, ROS↑,
1780- MEL,    Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing
- Review, Var, NA
*antiOx↑, *toxicity↓, ChemoSen↑, *eff↑, *mitResp↑, *ATP↑, *ROS↓, *CardioT↓, *GSH↑, *NOS2↓, *lipid-P↓, eff↑, *HO-1↑, *NRF2↑, *NF-kB↑, TumCP↓, eff↑, neuroP↑,
7495- MEL,    Melatonin: a promising neuroprotective agent for cerebral ischemia-reperfusion injury
- Review, Stroke, NA
*other↓, *neuroP↑, *Stroke↓, *Dose↝, *Risk↓, *cognitive↑,
6418- MEL,  RES,    Melatonin improves mitochondrial function by preventing mitochondrial fission in cadmium-induced rat proximal tubular cell injury via SIRT1-PGC-1α pathway activation
- in-vivo, AD, NA
*neuroP↑, *DRP1/DNM1L↓, *FIS1↓, *ROS↓, *MMP↑, *SIRT1↑, *PGC-1α↑, *eff↑,
4705- MEL,    Melatonin: beyond circadian regulation - exploring its diverse physiological roles and therapeutic potential
- Review, Nor, NA
*CLOCK↝, *BMD↑, *cardioP↑, *neuroP↑, *Sleep↑,
5795- MET,    Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes
- Review, AD, NA - Review, Park, NA - Review, Diabetic, NA
*AntiDiabetic↑, *AMPK↑, *glyC↓, *ROS↓, *cardioP↑, *neuroP↑, *Half-Life↝, *toxicity↝, *BioAv↑, *glucose↓, *AGEs↓, AntiCan↑, Risk↓, TumCP↓, Apoptosis↑, TumCCA↑, cycD1/CCND1↓, pRB↓, p27/CDKN1B↓, mTOR↓, Casp↑, ROS↑, MMP↓, ChemoSen↑, *hepatoP↑, *CRM↑, *Insulin↓,
2253- MF,    Low-frequency pulsed electromagnetic field promotes functional recovery, reduces inflammation and oxidative stress, and enhances HSP70 expression following spinal cord injury
- in-vivo, Nor, NA
*Inflam↓, *TNF-α↓, *IL1β↓, *NF-kB↓, *iNOS↓, *ROS↓, Catalase↑, *SOD↑, *HSP70/HSPA5↑, *neuroP↑, *motorD↑, *antiOx↑,
4096- MF,    Extremely Low‐Frequency and Low‐Intensity Electromagnetic Field Technology (ELF‐EMF) Sculpts Microtubules
- in-vitro, AD, NA
*p‑tau↓, *neuroP↑, *Dose↝,
4148- MF,    Increase in Blood Levels of Growth Factors Involved in the Neuroplasticity Process by Using an Extremely Low Frequency Electromagnetic Field in Post-stroke Patients
- Human, Stroke, NA
*neuroP↑, *BDNF↑, *Dose↝,
4094- MF,    EMAGINE-Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke
- Study, Stroke, NA
*neuroP↑, *Dose↝,
4105- MF,    Extremely low frequency electromagnetic fields stimulation modulates autoimmunity and immune responses: a possible immuno-modulatory therapeutic effect in neurodegenerative diseases
- Review, AD, NA
*Inflam↓, *neuroP↑, *NO↑, *ROS↓, *NO↓, *MCP1/CCL2↑, *HSP70/HSPA5↑, *antiOx↑, *NRF2↑, *NF-kB↓,
4147- MF,    PEMFs Restore Mitochondrial and CREB/BDNF Signaling in Oxidatively Stressed PC12 Cells Targeting Neurodegeneration
- in-vitro, AD, PC12
*ROS↓, *Catalase↑, *MMP↑, *Casp3↓, *p‑ERK↓, *cAMP↑, *p‑CREB↑, *BDNF↑, *neuroP↑,
4106- MF,    Cognitive Decline: Current Intervention Strategies and Integrative Therapeutic Approaches for Alzheimer's Disease
- Review, AD, NA
*cognitive↑, *memory↑, *Aβ↓, *neuroP↑,
4110- MF,    Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia
- Review, Stroke, NA
*ROS↓, *Inflam↓, *other↝, *neuroP↑, *Apoptosis↓, *Hif1a↝,
4118- MF,    Effects of transcranial magnetic stimulation on neurobiological changes in Alzheimer's disease
- Review, AD, NA
*cognitive↑, *BDNF↑, *neuroP↑, *memory↑, *ROS↓, *antiOx↑, *Aβ↓, *eff↑,
4101- MF,    Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation
- Human, Stroke, NA
*motorD↑, *cognitive↑, *eff↑, *NO↑, *other↝, *neuroP↑,
3728- MF,    Long-term exposure to ELF-MF ameliorates cognitive deficits and attenuates tau hyperphosphorylation in 3xTg AD mice
- in-vivo, AD, NA
*cognitive↑, *neuroP↑, *Apoptosis↓, *ROS↓, *p‑tau↓, *GSK‐3β↓, *CDK5↓,
3724- MF,  RF,    Electromagnetic Field in Alzheimer's Disease: A Literature Review of Recent Preclinical and Clinical Studies
- Review, AD, NA
*memory↑, *neuroP↑,
3476- MF,    Pulsed Electromagnetic Fields Stimulate HIF-1α-Independent VEGF Release in 1321N1 Human Astrocytes Protecting Neuron-like SH-SY5Y Cells from Oxygen-Glucose Deprivation
- in-vitro, Stroke, 1321N1 - in-vitro, Park, NA
*VEGF↑, *eff↑, *neuroP↑, *other↑, *eff↑, *Inflam↓, *Hif1a∅,
3475- MF,    A Pulsed Electromagnetic Field Protects against Glutamate-Induced Excitotoxicity by Modulating the Endocannabinoid System in HT22 Cells
- in-vitro, Nor, HT22 - Review, AD, NA
*Apoptosis↓, *LDH↓, *neuroP↑, *toxicity∅, *IL1β↓, *Inflam↓, *IL10↑, *TNF-α↓,
204- MFrot,  MF,    Rotating magnetic field improved cognitive and memory impairments in a sporadic ad model of mice by regulating microglial polarization
- in-vivo, AD, NA
*NF-kB↓, *MAPK↓, *TLR4↓, *memory↑, *cognitive↑, *TGF-β1↑, *ARG1/2↑, *IL4↑, *IL10↑, *IL6↓, *IL1↓, *TNF-α↓, *iNOS↓, *ROS↓, *NO↓, *MyD88↓, *p‑IKKα↓, *p‑IκB↓, *p‑p65↓, *p‑JNK↓, *p‑p38↓, *ERK↓, *neuroP↑, *Aβ↓,
3488- MFrot,  MF,    Rotating magnetic field improves cognitive and memory impairments in APP/PS1 mice by activating autophagy and inhibiting the PI3K/AKT/mTOR signaling pathway
- in-vivo, AD, NA
*cognitive↑, *memory↑, *neuroP↑, *Aβ↓, *PI3K↓, *Akt↓, *mTOR↓,
3567- MFrot,  MF,    The Effect of Extremely Low-Frequency Magnetic Field on Stroke Patients: A Systematic Review
- Review, Stroke, NA
*eff↑, *ROS↓, *Inflam↓, *cognitive↑, *Catalase↑, *SOD↑, *SOD1↑, *SOD2↑, *GPx1↑, *GPx4↑, *IL1β↑, *neuroP↑, *toxicity∅,
3745- MFrot,  MF,    The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *5HT↑, *cFos↑, *Aβ↓, *memory↑, *BDNF↑, *Ach↑, *AChE↓, *cognitive↑, *BDNF↑, *NGF↑, *β-catenin/ZEB1↑, *p‑Akt↓, *mTOR↓, *MMP1↓, *MMP9↓, *MMP-10↓, *TIMP1↑, *TIMP2↑,
3838- Moringa,    Characterization, Large-Scale HSCCC Separation and Neuroprotective Effects of Polyphenols from Moringa oleifera Leaves
- in-vitro, AD, PC12 - Review, Stroke, NA
*Inflam↓, *neuroP↑, *antiOx↑, *ROS↓, *memory↑, *MDA↓, *AChE↓, *SOD↑, *Catalase↑, *eff↑,
3837- Moringa,    Moringa oleifera: A Tree of Life as a Promising Medicinal Plant for Neurodegenerative Diseases
- Review, AD, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *AntiTum↑, *hepatoP↑, *cardioP↑, *neuroP↑,
3834- Moringa,    Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *Aβ↓, *BACE/β-secretase↓, *cal2↓, *p‑tau↓, *ROS↓, *SOD↑, *MDA↓, *cognitive↑, *memory↑,
3835- Moringa,    Moringa Oleifera Alleviates Aβ Burden and Improves Synaptic Plasticity and Cognitive Impairments in APP/PS1 Mice
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *AChE↓, *neuroP↑, *Mood↑, *cognitive↑, *memory↑, *Aβ↓, *BACE/β-secretase↓, *AEP↓, *IDE↑, *NEP↑, *LRP1↑, *PSD95↑, *STEP↓, *APP↓,
3839- Moringa,    Nutritional Value of Moringa oleifera Lam. Leaf Powder Extracts and Their Neuroprotective Effects via Antioxidative and Mitochondrial Regulation
*eff↑, *ROS↓, *lipid-P↓, *GSH↑, *antiOx↑, *Ca+2↓, *MMP↑, *neuroP↑, *BBB↑, *Catalase↑, *SOD↑, GPx↑,
3840- Moringa,    Moringa oleifera Mitigates Memory Impairment and Neurodegeneration in Animal Model of Age-Related Dementia
- in-vivo, AD, NA
*antiOx↑, *memory↑, *neuroP↑, *MDA↓, *AChE↓, *SOD↑, *Catalase↑, *cognitive↑, *ROS↓, *Ach↑,
3841- Moringa,    Cerebroprotective effect of Moringa oleifera against focal ischemic stroke induced by middle cerebral artery occlusion
- in-vivo, Stroke, NA
*MDA↓, *SOD↑, *neuroP↑, *ROS↓, *Inflam↓, *eff↝,
4226- Moringa,    The Oil Formulation Derived from Moringa Oleifera Seeds Ameliorates Behavioral Abnormalities in Water-immersion Restraint Stress Mouse Model
- in-vivo, NA, NA
*neuroP↑, *Mood↑, *BDNF↑, *AChE↓, *MDA↓,

Showing Research Papers: 451 to 500 of 725
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 725

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,   Catalase↑, 1,   CYP1A1↓, 1,   GPx↑, 1,   GSR↓, 1,   H2O2↓, 1,   NOX4↓, 1,   NRF2↓, 1,   OXPHOS↑, 1,   mt-OXPHOS↑, 1,   ROS↓, 2,   ROS↑, 3,   ROS⇅, 1,  

Mitochondria & Bioenergetics(tgid=3)

MMP↓, 2,   OCR↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

ACC↓, 1,   AMPK↑, 2,   ECAR↓, 1,   Glycolysis↓, 1,   lactateProd↓, 2,   LDH↓, 1,   NADPH↓, 1,   PPARγ↓, 1,   Warburg↓, 2,  

Cell Death(tgid=5)

Akt↓, 2,   Apoptosis↑, 4,   Bcl-2↓, 1,   Casp↑, 1,   Casp3↑, 1,   Cyt‑c↝, 1,   MAPK↓, 1,   p27/CDKN1B↓, 1,  

Transcription & Epigenetics(tgid=7)

KISS1↑, 1,   other↓, 1,   pRB↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 1,   DNAdam↑, 1,   DNArepair↑, 1,   P53↓, 1,   PCNA↓, 2,  

Cell Cycle & Senescence(tgid=11)

CDK2↓, 2,   CDK4↓, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 1,   cycD1/CCND1↓, 5,   P21↑, 1,   TumCCA↑, 6,  

Proliferation, Differentiation & Cell State(tgid=12)

mTOR↓, 2,   PI3K↓, 1,   STAT3↓, 1,   TumCG↓, 4,  

Migration(tgid=13)

Akt2↓, 1,   Ca+2↑, 1,   E-cadherin↑, 1,   Ki-67↓, 2,   MMP2↓, 4,   MMP7↓, 2,   MMP9↓, 4,   Rho↓, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TumCI↓, 2,   TumCMig↓, 2,   TumCP↓, 7,  

Angiogenesis & Vasculature(tgid=14)

Hif1a↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 1,   NF-kB↓, 4,   PGE2↓, 2,   PSA↓, 1,  

Cellular Microenvironment(tgid=17)

NOX↓, 1,  

Synaptic & Neurotransmission(tgid=18)

tau↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 2,   BioAv↑, 2,   ChemoSen↑, 3,   Dose↝, 2,   Dose∅, 1,   eff↑, 4,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22)

Ki-67↓, 2,   LDH↓, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 2,   AntiDiabetic↑, 1,   AntiTum↑, 1,   cardioP↑, 2,   chemoP↑, 1,   ChemoSideEff↓, 1,   hepatoP↑, 1,   neuroP↑, 7,   OS↑, 1,   radioP↑, 1,   Remission↑, 1,   Risk↓, 1,  
Total Targets: 95

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

Stroke↓, 2,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 21,   mt-antiOx↑, 1,   Catalase↑, 8,   CYP2E1↓, 1,   GPx↑, 3,   GPx1↑, 1,   GPx4↑, 1,   GSH↑, 5,   GSR↑, 1,   GSTs↓, 1,   GSTs↑, 1,   H2O2↓, 1,   HO-1↑, 4,   hyperG↓, 1,   lipid-P↓, 3,   MDA↓, 9,   MPO↓, 1,   NOX4↓, 1,   NQO1↑, 1,   Nrf1↑, 1,   NRF2↑, 8,   ROS↓, 29,   ROS⇅, 1,   SOD↑, 11,   SOD1↑, 1,   SOD2↑, 1,   TAC↑, 2,   VitC↑, 1,   VitE↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

ATP↑, 1,   DRP1/DNM1L↓, 1,   FIS1↓, 1,   Insulin↓, 1,   mitResp↑, 1,   MMP↓, 1,   MMP↑, 3,   mtDam↓, 1,   OCR↓, 1,   OCR↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

ACC↓, 1,   ALAT↓, 1,   AMPK↑, 1,   cAMP↑, 1,   p‑CREB↑, 1,   CRM↑, 2,   ECAR↓, 1,   FASN↓, 1,   glucose↓, 2,   GlucoseCon↑, 1,   glyC↓, 1,   Glycolysis↓, 1,   LDH↓, 1,   LDL↓, 1,   PPARγ↓, 1,   PPARγ↑, 1,   SIRT1↑, 1,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5)

Akt↓, 3,   p‑Akt↓, 1,   Apoptosis↓, 4,   Casp3↓, 1,   iNOS↓, 4,   JNK↓, 2,   p‑JNK↓, 1,   MAPK↓, 3,   p‑p38↓, 1,  

Transcription & Epigenetics(tgid=7)

Ach↑, 2,   other↓, 1,   other↑, 1,   other↝, 2,  

Protein Folding & ER Stress(tgid=8)

HSP70/HSPA5↑, 2,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

cFos↑, 1,   CLOCK↝, 1,   ERK↓, 2,   p‑ERK↓, 1,   GSK‐3β↓, 1,   mTOR↓, 4,   PI3K↓, 2,   STAT3↓, 1,  

Migration(tgid=13)

APP↓, 1,   ARG1/2↑, 1,   Ca+2↓, 2,   Ca+2↝, 1,   cal2↓, 1,   CDK5↓, 1,   Ki-67↓, 1,   LRP1↑, 1,   MMP-10↓, 1,   MMP1↓, 1,   MMP2↑, 1,   MMP9↓, 1,   ROCK1↓, 1,   TGF-β1↑, 2,   TIMP1↑, 1,   TIMP2↑, 1,   VCAM-1↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   Hif1a↝, 1,   Hif1a∅, 1,   NO↓, 4,   NO↑, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15)

BBB↑, 4,  

Immune & Inflammatory Signaling(tgid=16)

COX2/PTGS2↓, 2,   ICAM-1↓, 2,   p‑IKKα↓, 1,   IL1↓, 4,   IL10↑, 4,   IL1β↓, 4,   IL1β↑, 1,   IL22↓, 1,   IL4↑, 1,   IL6↓, 5,   IL8↓, 3,   Imm↑, 1,   Inflam↓, 19,   Inflam↑, 1,   p‑IκB↓, 1,   MCP1/CCL2↑, 1,   MyD88↓, 1,   NF-kB↓, 11,   NF-kB↑, 1,   p‑p65↓, 1,   PGE2↓, 1,   TLR2↓, 2,   TLR4↓, 3,   TNF-α↓, 7,  

Synaptic & Neurotransmission(tgid=18)

5HT↑, 1,   AChE↓, 6,   AChE↑, 1,   BDNF↑, 11,   NGF↑, 1,   PSD95↑, 1,   tau↓, 1,   p‑tau↓, 4,  

Protein Aggregation(tgid=19)

AEP↓, 1,   AGEs↓, 2,   Aβ↓, 9,   BACE/β-secretase↓, 3,   IDE↑, 1,   NEP↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 2,   Dose↓, 1,   Dose↑, 1,   Dose↝, 7,   eff↑, 11,   eff↝, 2,   Half-Life↑, 1,   Half-Life↝, 1,   P450↑, 1,  

Clinical Biomarkers(tgid=22)

ALAT↓, 1,   AST↓, 1,   BMD↑, 1,   BP↓, 1,   creat↓, 1,   GutMicro↑, 1,   IL6↓, 5,   Ki-67↓, 1,   LDH↓, 1,   NOS2↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 4,   AntiDiabetic↑, 2,   AntiTum↑, 1,   cardioP↑, 8,   CardioT↓, 1,   cognitive↑, 17,   hepatoP↑, 4,   memory↑, 16,   Mood↑, 2,   motorD↑, 2,   neuroP↑, 44,   RenoP↑, 2,   Risk↓, 1,   Sleep↑, 1,   STEP↓, 1,   toxicity↓, 2,   toxicity↝, 1,   toxicity∅, 3,  

Infection & Microbiome(tgid=24)

Bacteria↓, 2,  
Total Targets: 185

Scientific Paper Hit Count for: neuroP, neuroprotective
23 Resveratrol
21 Thymoquinone
20 Alpha-Lipoic-Acid
19 Quercetin
18 Magnetic Fields
16 Hydrogen Gas
16 Silymarin (Milk Thistle) silibinin
15 Chlorogenic acid
15 Ferulic acid
15 Urolithin
14 Curcumin
13 Rosmarinic acid
11 Baicalein
11 Fisetin
11 Kaempferol
11 Lycopene
10 Ashwagandha(Withaferin A)
10 Mung Bean Sprouts
10 Carvacrol
10 Crocetin
10 EGCG (Epigallocatechin Gallate)
10 Honokiol
9 Berberine
9 Bacopa monnieri
9 Chrysin
8 isoquercitrin
8 Emodin
8 Moringa oleifera
8 Sulforaphane (mainly Broccoli)
7 Allicin (mainly Garlic)
7 Caffeic acid
7 Centella asiatica / Gotu kola → asiaticoside
7 Piperine
7 Huperzine A/Huperzia serrata
7 Taurine
6 Apigenin (mainly Parsley)
6 Selenium NanoParticles
6 Cysteamine
6 Ginkgo biloba-EGb 761
6 Eugenol
6 Folic Acid, Vit B9
6 Ginkgo biloba
6 Ginkgolide B
6 Ginseng
6 Isoliquiritigenin
6 Luteolin
6 Mushroom Lion’s Mane
6 Phenylbutyrate
6 Silicic Acid
5 Astaxanthin
5 Beta-Caryophyllene
5 Vitamin C (Ascorbic Acid)
5 α-Bisabolol / Chamomile oil
5 Capsaicin
5 Hydroxycinnamic-acid
5 Hyperoside
5 Isovitexin
5 Vitexin
5 Melatonin
5 Piperlongumine
5 Shankhpushpi
5 Shikonin
5 Vitamin E
5 Vitamin B5,Pantothenic Acid
4 Rutin
4 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
4 Boron
4 Boswellia (frankincense)
4 Carnosic acid
4 Carnosine
4 Propolis -bee glue
4 Shilajit/Fulvic Acid
4 Magnetic Field Rotating
4 Pterostilbene
4 Vitamin B12
3 Anthocyanins
3 Artemisinin
3 Biochanin A
3 Betulinic acid
3 Vitamin B6,pyridoxine
3 Caffeic Acid Phenethyl Ester (CAPE)
3 Exercise
3 Celastrol
3 Cichoric acid / Chicoric acid
3 Cinnamon
3 Coenzyme Q10
3 diet Short Term Fasting
3 Fucoidan
3 Ginkgetin
3 HydroxyTyrosol
3 isoorientin
3 Licochalcone A
3 Methylene blue
3 Magnolol
3 nicotinamide adenine dinucleotide
3 Selenite (Sodium)
3 Ursolic acid
2 1,8-Cineole
2 Anethole/trans-Anethole
2 Baicalin
2 beta-carotene(VitA)
2 borneol
2 Thymol-Thymus vulgaris
2 Chlorophyllin
2 Choline
2 Calorie Restriction Mimetics
2 Spermidine
2 Cucurbitacin
2 Metformin
2 Date Fruit Extract
2 D-limonene
2 Dandelion Root
2 Ellagic acid
2 Angelica archangelica / Garden Angelica
2 flavonoids
2 Flickering Light Stimulation
2 Formononetin
2 Gamma-aminobutyric acid
2 Geraniol
2 hydrogen sulfide
2 Oleuropein
2 Isobavachalcone
2 EMF
2 Naringin
2 Nimbolide
2 Phenolic Acids
2 Phosphatidylserine
2 Chemotherapy
2 Vitamin D3
2 Vitamin K2
1 Annona atemoya Leaf Extract
1 Astragalus
1 alpha Linolenic acid
1 Aluminum
1 Fennel Oil/Foeniculum vulgare
1 doxorubicin
1 xanthohumol
1 Butyrate
1 Paclitaxel/Taxol
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chitosan
1 Chyawanprash
1 Selenium
1 Carica papaya leaf extract
1 Aspirin
1 Carvone
1 Cynara scolymus/Globe Artichoke/Artichoke Extract
1 Silver-NanoParticles
1 Dichloroacetate
1 Bortezomib
1 Diclofenac
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet Methionine-Restricted Diet
1 diet FMD Fasting Mimicking Diet
1 Eurycomanone
1 Evodiamine
1 Gallic acid
1 Garcinol
1 Genistein (soy isoflavone)
1 Ginger/6-Shogaol/Gingerol
1 Germacranolide sesquiterpene lactone
1 Helleborus niger extracts – Christmas Rose
1 Inulin Prebiotic
1 Bifidobacterium animalis subsp. lactis GCL2505
1 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
1 Butein
1 Scopoletin
1 isoflavones
1 Morin
1 Ivermectin
1 Lactoferrin/Talactoferrin
1 MCToil
1 Methylsulfonylmethane
1 Myricetin
1 Neem
1 Olive Oil
1 Protocatechuic acid
1 Polyphenols
1 Psoralidin
1 Sinapic acid
1 Salvia officinalis
1 Aromatherapy
1 Sesame seeds and Oil
1 Anti-oxidants
1 Aflavin-3,3′-digallate
1 Turmerones
1 Vanillic Acid
1 Vitamin A, Retinoic Acid
1 Vitamin B1/Thiamine
1 Vitamin B3,Niacin
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1105  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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