Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
Source:
Type:
Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
6428- FEO,  Eug,    Triggering of apoptosis and cell cycle arrest by fennel and clove oils in Caco-2 cells: the role of combination
- in-vitro, Colon, Caco-2
TumCCA↑, Apoptosis↑, Dose↝, TumCCA↑, Ki-67↓,
6890- Fer,    Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues
- vitro+vivo, Var, NA
TumMeta↓, TumCD∅, Casp3↑, ROS↑, H2O2↑, TumCG↓, Dose↝, other↑,
6917- FIS,    Dietary flavonoid fisetin regulates aluminium chloride-induced neuronal apoptosis in cortex and hippocampus of mice brain
- in-vivo, AD, NA - in-vivo, Park, NA
*neuroP↑, *Dose↝, *Aβ↓, *ASK1↓, *p‑JNK↓, *P53↓, *Cyt‑c↓, *Casp9↓, *Bax:Bcl2↝,
6920- FIS,    A phase II randomized placebo-controlled study of fisetin to improve physical function in breast cancer survivors: the TROFFi study rationale and trial design
- Trial, BC, NA
Dose↝, cellSen?,
6921- FIS,    The Effects of Fisetin on Reducing Biological Aging: A Pilot Study
- Human, Nor, NA
*Dose↝, *AntiAge⇅,
6901- FIS,    Fisetin induces G2/M phase arrest and caspase-mediated cleavage of p21Cip1 and p27Kip1 leading to apoptosis and tumor growth inhibition in HNSCC
- in-vivo, HNSCC, CAL33
TumCG↓, TumCD↑, selectivity↑, TumCCA↑, CDC25↓, CDK1↓, CycB/CCNB1↓, P53↑, DNAdam↑, Apoptosis↑, γH2AX↑, cl‑PARP↑, other↝, JNK↑, PI3K↓, Akt↓, ERK↓, EGFR↓, STAT3↓, TumAuto↑, Dose↝, TumVol↓, Ki-67↓, cl‑Casp3↑, P21↓, p27/CDKN1B↓,
6899- FIS,    Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, PC3 - in-vitro, Pca, 22Rv1
Dose↝, tumCV↓, selectivity↑, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↑, CDK4↑, CDK6↑, P21↑, p27/CDKN1B↑, Apoptosis↑, cl‑PARP↑, Cyt‑c↑, XIAP↓, Casp3↑, Casp8↑, Casp9↑, Bcl-2↓, PI3K↓, Akt↓,
2854- FIS,    New Perspectives for Fisetin
- Review, Var, NA - Review, Stroke, NA
Inflam↓, ChemoSen↑, chemoPv↑, eff↑, memory↑, neuroP↑, *Dose↑, BioAv↓, BBB↑,
2827- FIS,    The Potential Role of Fisetin, a Flavonoid in Cancer Prevention and Treatment
- Review, Var, NA
*antiOx↑, *Inflam↓, neuroP↑, hepatoP↑, RenoP↑, cycD1/CCND1↓, TumCCA↑, MMPs↓, VEGF↓, MAPK↓, NF-kB↓, angioG↓, Beclin-1/ATG6↑, LC3s↑, ATG5↑, Bcl-2↓, BAX↑, Casp↑, TNF-α↓, Half-Life↓, MMP↓, mt-ROS↑, cl‑PARP↑, CDK2↓, CDK4↓, Cyt‑c↑, Diablo↑, DR5↑, Fas↑, PCNA↓, Ki-67↓, p‑H3↓, chemoP↑, Ca+2↑, Dose↝, CDC25↓, CDC2↓, CHK1↑, Chk2↑, ATM↑, PCK1↓, RAS↓, p‑p38↓, Rho↓, uPA↓, MMP7↓, MMP13↓, GSK‐3β↑, E-cadherin↑, survivin↓, VEGFR2/KDR/Flk1↓, IAP2/BIRC3↓, STAT3↓, JAK1↓, mTORC1↓, mTORC2↓, NRF2↑,
2828- FIS,    Fisetin, a Potent Anticancer Flavonol Exhibiting Cytotoxic Activity against Neoplastic Malignant Cells and Cancerous Conditions: A Scoping, Comprehensive Review
- Review, Var, NA
*neuroP↑, *antiOx↑, *Inflam↓, RenoP↑, COX2/PTGS2↓, Wnt↓, EGFR↓, NF-kB↓, Casp3↑, Ca+2↑, Casp8↑, TumCCA↑, CDK1↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, *P53↓, *P21↓, *p16↓, mTORC1↓, mTORC2↓, P53↑, P21↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, CDK4↓, BAX↑, Bcl-2↓, PCNA↓, HER2/EBBR2↓, Cyt‑c↑, MMP↓, cl‑Casp9↑, MMP2↓, MMP9↓, cl‑PARP↑, uPA↓, DR4↑, DR5↑, ROS↓, AIF↑, CDC25↓, Dose↑, CHOP/DDIT3↑, ROS↑, cMyc↓, cardioP↑,
6930- FLS,    40 Hz light flickering facilitates the glymphatic flow via adenosine signaling in mice
*GlyFlow↑, *e-ADO↑, *Sleep↑, *Dose↝, *AQPs↑, BloodF↑,
6933- FLS,  AudGS,    Gamma sensory stimulation in mild Alzheimer's dementia: An open-label extension study
- Trial, AD, NA
*Dose↝, *toxicity↓, *cognitive↑,
6982- Form,    Formononetin: A Review of Its Anticancer Potentials and Mechanisms
- Review, Var, NA
AntiTum↑, Apoptosis↑, BAX↑, Bcl-2↓, Casp3↑, TumCCA↑, cycA1/CCNA1↓, CycB/CCNB1↓, cycD1/CCND1↓, TumCP↓, VEGF↓, FGF↓, MMP2↓, MMP9↓, eff↑, ChemoSen↑, chemoPv↑, p‑Akt↓, p‑STAT3↑, TumCMig↓, TumCI↓, TIMP1↑, TIMP2↑, PI3K↓, Akt↓, Dose↝, TumCG↓, TumW↓, TumVol↓, angioG↓, Casp3↑, Casp9↑, cl‑PARP↑, DNArepair↓, MMP↓, BAX↑, Bcl-2↓, DR5↑, ROS↑, eff↓, p‑ERK↓, PTEN↑, Hif1a↓, eff↑, eff↑, ChemoSen↑, HDAC↓, *BioAv↑, *Half-Life↝, *BioAv↝, *BioAv↑, *BioAv↑, *eff↑,
6987- Form,    Formononetin exhibits anticancer activity in gastric carcinoma cell and regulating miR-542-5p
- vitro+vivo, GC, SGC-7901 - in-vitro, BC, MGC803
antiNeop↑, tumCV↓, TumCMig↓, TumCI↓, Dose↝, miR-542↓, TumCG↓,
6964- Form,    Formononetin induces cell cycle arrest of human breast cancer cells via IGF1/PI3K/Akt pathways in vitro and in vivo
- vitro+vivo, BC, MCF7
IGF-1↓, IGFR↓, PI3K↓, Akt↓, cycD1/CCND1↓, TumCP↓, TumCCA↑, TumCG↓, Dose↝,
6967- Form,  BTZ,    Formononetin Regulates Multiple Oncogenic Signaling Cascades and Enhances Sensitivity to Bortezomib in a Multiple Myeloma Mouse Model
- in-vivo, Melanoma, U266 - in-vivo, Melanoma, RPMI-8226
eff↑, NF-kB↓, PI3K↓, Akt↓, AP-1↓, COX2/PTGS2↓, MMP9↓, Casp3↑, cl‑PARP↑, Dose↝, Ki-67↓, VEGF↓,
6969- Form,    Formononetin inhibits tumor growth by suppression of EGFR-Akt-Mcl-1 axis in non-small cell lung cancer
- vitro+vivo, NSCLC, HCC827 - in-vitro, NSCLC, A549 - in-vitro, Lung, H1299
EGFR↓, Akt↓, GSK‐3β↑, TumCG↓, ChemoSen↑, Mcl-1↓, RadioS↑, tumCV↓, selectivity↑, Dose↝, Cyt‑c↑, BAX↑, Apoptosis↑, Ki-67↓, toxicity↓, chemoPv↑,
6971- Form,    In vitro and in vivo anti-cancer activity of formononetin on human cervical cancer cell line HeLa
- vitro+vivo, Cerv, HeLa
p‑Akt↓, Apoptosis↑, TumCG↓, Dose↝, PI3K↓, eff↑, ATP↓, OCR↓, TumCCA↑, IGF-1↓, angioG↓, TumCI↓,
6972- Form,  PacT,    Formononetin ameliorates the drug resistance of Taxol resistant triple negative breast cancer by inhibiting autophagy
- in-vivo, BC, MDA-MB-231
AntiCan↑, miR-199↓, ChemoSen↑, TumVol↓, Dose↝, TumCG↓, TumCCA↑, Apoptosis↑, TumAuto↓, eff↓,
7011- Fuc,  ATO,  VitA,RetA,    Fucoidan enhances the therapeutic potential of arsenic trioxide and all-trans retinoic acid in acute promyelocytic leukemia, in vitro and in vivo
- NA, APL, APL NB4 - vitro+vivo, NA, NA
TumCCA↑, DNAdam↑, TumCP↓, Apoptosis↑, Diff↑, CD11b↑, eff↑, Dose↝,
7012- Fuc,    Fucoidan: A promising natural therapeutic agent for protecting human kidney health
- Review, EC, NA
*RenoP↑, *Inflam↓, *antiOx↑, *ROS↓, *BloodF↑, *diuretic↑, *BioAv↓, *BioAv↑, *MAPK↓, *ERK↑, *NLRP3↓, *NRF2↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *lipid-P↓, *DNAdam↓, *Fibrosis↓, *JAK2↓, *STAT3↓, *uricA↓, *COL1↓, *α-SMA↓, *SIRT1↑, *HO-1↑, *GLP-1R↑, *HMGB1↓, *RAGE↓, *NF-kB↓, *TGF-β1↓, *PI3K↓, *Akt↓, *GutMicro↑, *SCFAs↑, *Buty↑, *IBI↑, *TJ↑, *Dose↝,
7014- Fuc,  5-FU,    Low-Molecular-Weight Fucoidan as Complementary Therapy of Fluoropyrimidine-Based Chemotherapy in Colorectal Cancer
- in-vitro, CRC, HCT116 - in-vitro, Colon, Caco-2
tumCV↓, ChemoSen↑, TumCCA↑, cl‑PARP↑, KRAS↓, p‑ERK↓, PI3K↓, p‑Akt↓, TumCMig↓, MMP2↓, Dose↝,
7016- Fuc,    Therapies from Fucoidan: New Developments
- Review, Var, NA
*Bacteria↓, *BioAv↓, *Dose↝, *GutMicro↑, PD-1↝, ROS⇅, cl‑Casp↑, cl‑PARP↑, RadioS↑, *radioP↑, *neuroP↑, *Aβ↓,
7018- Fuc,    Absorption Study of Mozuku Fucoidan in Japanese Volunteers
- Trial, Nor, NA
*Dose↝, *BioAv↝, *eff↝, *Inflam↓, *AntiThr↑, angioG↓, *AntiViral↑, *AntiTum↑, *antiOx↓, *BioAv↝,
7025- Fuc,    Pilot clinical study to evaluate the anticoagulant activity of fucoidan
- Human, Nor, NA
*Dose↝, *BioAv↓, *antiCG↝,
7021- Fuc,    Fucoidan Prevents the Progression of Osteoarthritis in Rats
- in-vivo, Arthritis, NA
*Dose↝, *Cartilage↑, *TNF-α↓, *IL1β↓, *MMP1↓,
7007- Fuc,    The Therapeutic Potential of the Anticancer Activity of Fucoidan: Current Advances and Hurdles
- Review, Var, NA
TumCCA↑, Apoptosis↑, NK cell↑, chemoP↑, TumCG↓, *Inflam↓, *antiOx↑, *AntiThr↑, *AntiViral↑, angioG↓, ChemoSen↑, ROS↑, GSH↓, mtDam↓, MMP↓, DNMT3B↓, TumCG↓, Dose↝, Dose↝, QoL∅, fatigue∅, Dose↝,
4023- FulvicA,    Shilajit (Mumio) Elicits Apoptosis and Suppresses Cell Migration in Oral Cancer Cells through Targeting Urokinase-type Plasminogen Activator and Its Receptor and Chemokine Signaling Pathways
- in-vitro, Oral, NA
tumCV↓, selectivity↑, Apoptosis↑, uPA↓, TumCMig↓, Dose↝, CXCc↓,
4026- FulvicA,    Shilajitin Cancer Treatment: Probable Mode of Action
- Review, Var, NA
*Inflam↓, *antiOx↑, Dose↝,
4028- FulvicA,    Mineral pitch induces apoptosis and inhibits proliferation via modulating reactive oxygen species in hepatic cancer cells
- in-vitro, Liver, HUH7
Apoptosis↑, TumCP↓, ROS↑, NO↑, Dose↝, MMP↓, Cyt‑c↑, SOD↓, Catalase↓, GSH↑, lipid-P↑, miR-21↓, miR-22↑,
4016- FulvicA,    Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
- Review, AD, NA
*tau↓, *AntiAge↑, *Strength↑, *Dose↝, *BioAv↑, *antiOx↑, *memory↑, *Inflam↓, *cognitive↑, *neuroP↑, *toxicity↝, *toxicity↑,
1624- GA,    Anticancer Effect of Pomegranate Peel Polyphenols against Cervical Cancer
- in-vitro, Cerv, NA
ROS↑, Dose∅, MMP↓, GSH↑,
7044- GA,  QC,    Inhibitory effects of gallic acid and quercetin on UDP-glucose dehydrogenase activity
- in-vitro, BC, MCF7
UGDH↓, UGDH↓, TumCP↓, Dose↑, *BioAv↓, eff?,
7032- GA,  Cisplatin,    Gallic acid: a polyphenolic compound potentiates the therapeutic efficacy of cisplatin in human breast cancer cells
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10
ChemoSen↑, tumCV↓, Apoptosis↑, selectivity↑, *ROS↓, eff↑, *chemoP↑, Dose↝,
7833- GA,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *Dose↝, *ADAM10↝, *BACE/β-secretase↓, *cl‑APP↓, *Aβ↓, *Ca+2↓, *ROS↓, *NeuroI↓,
7072- GABA,  CHOC,    Psychological stress-reducing effect of chocolate enriched with gamma-aminobutyric acid (GABA) in humans: assessment of stress using heart rate variability and salivary chromogranin A
- Trial, Nor, NA
*Dose↝, *Stress↓,
7071- GABA,    Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks
- Trial, Nor, NA
*memory↑, *BP↓, *Dose↝, *Stress↓,
7075- GABA,    Effects of γ-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial
- Trial, Diabetic, NA
*Dose↝, *glucose∅,
7076- GABA,    Anti-hypertensive effect of gamma-aminobutyric acid (GABA)-rich Chlorella on high-normal blood pressure and borderline hypertension in placebo-controlled double blind study
- Trial, Nor, NA
*Dose↝, *BP↓, *eff↑,
7077- GABA,    GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial
- Trial, Nor, NA
*Sleep↑, *Dose↝, *other↝,
7080- GABA,    The Effect of Oral GABA on the Nervous System: Potential for Therapeutic Intervention
- Review, AD, NA
*BBB↝, *cognitive↑, *Dose↝, *toxicity↓, *Stress↓, *Inflam↓, *iNOS↓, *COX2/PTGS2↓, *IL6↓, *IL1β↓, *TNF-α↓, *Sleep↑, *Pain↓, *neuroP↑, *eff↑, *Ach↑, *AST↓, *ALAT↓, *BP↓, *other↝,
7081- GABA,    Exploring the Therapeutic Potential of Gamma-Aminobutyric Acid in Stress and Depressive Disorders through the Gut–Brain Axis
- Review, AD, NA
*other↝, *Sleep↑, *Stress↓, *cognitive↑, *other↝, *other↝, *other↑, *other↑, *memory↑, *Dose↝, *eff↑,
1954- GamB,    Gambogic acid induces apoptosis in hepatocellular carcinoma SMMC-7721 cells by targeting cytosolic thioredoxin reductase
- in-vitro, HCC, SMMC-7721 cell
AntiTum↑, TrxR↓, TrxR1↓, ROS↑, Apoptosis↑, Dose∅, Dose?,
1955- GamB,    Gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145
ROS↑, Apoptosis↑, Ferroptosis↑, Trx↓, eff↑, TrxR↓, Dose∅, MMP↓, eff↑, Casp↑, NADPH↓, TrxR↓, ChemoSen↑, AR↓,
7054- GamB,    An open-labeled, randomized, multicenter phase IIa study of gambogic acid injection for advanced malignant tumors
- Trial, Var, NA
Dose↝, DCR↝,
7085- GAR,    Safety profile of 40% Garcinol from Garcinia indica in experimental rodents
- in-vivo, Nor, NA
*Dose↓, *toxicity↓,
7084- GAR,    A unique in vivo pharmacokinetic profile, in vitro metabolic stability and hepatic first-pass metabolism of garcinol, a promising novel anticancer phytoconstituent, by liquid chromatography–mass spectrometry
- in-vivo, Nor, NA
*BioAv↝, *Dose↝, *Inflam↓, *antiOx↑, *chemoPv↑, Wnt↓, β-catenin/ZEB1↓, ERK↓, PI3K↓, Akt↓, NF-kB↓, STAT3↓, TumCP↓, antiNeop↑, ChemoSen↑, chemoP↑,
1636- GAR,    Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation
- Case Report, Obesity, NA
*Dose∅, *other↑,
7198- GBE,    Ginkgo biloba extract suppresses hepatocellular carcinoma progression by inhibiting the recruitment of myeloid-derived suppressor cells through reduced CXCL1 secretion via SRC downregulation
- vitro+vivo, HCC, NA
TumCG↓, Src↓, CXCL1↓, Dose↝,
7187- GBE,    Ginkgo biloba for prevention of dementia: a randomized controlled trial
- Trial, AD, NA
*Dose↝, Risk∅, eff∅,

Showing Research Papers: 451 to 500 of 1061
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1061

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

DCR↝, 1,   miR-199↓, 1,   miR-542↓, 1,   UGDH↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↓, 1,   Ferroptosis↑, 1,   GSH↓, 1,   GSH↑, 2,   H2O2↑, 1,   lipid-P↑, 1,   NRF2↑, 1,   ROS↓, 1,   ROS↑, 8,   ROS⇅, 1,   mt-ROS↑, 1,   SOD↓, 1,   Trx↓, 1,   TrxR↓, 3,   TrxR1↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   ATP↓, 1,   CDC2↓, 1,   CDC25↓, 3,   MMP↓, 7,   mtDam↓, 1,   OCR↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,   NADPH↓, 1,   PCK1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 8,   p‑Akt↓, 3,   Apoptosis↑, 14,   BAX↑, 5,   Bcl-2↓, 5,   Casp↑, 2,   cl‑Casp↑, 1,   Casp3↑, 6,   cl‑Casp3↑, 1,   Casp8↑, 2,   Casp9↑, 2,   cl‑Casp9↑, 1,   Chk2↑, 1,   Cyt‑c↑, 5,   Diablo↑, 1,   DR4↑, 1,   DR5↑, 3,   Fas↑, 1,   Ferroptosis↑, 1,   IAP2/BIRC3↓, 1,   JNK↑, 1,   MAPK↓, 2,   Mcl-1↓, 1,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 1,   p‑p38↓, 1,   survivin↓, 1,   TumCD↑, 1,   TumCD∅, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

p‑H3↓, 1,   miR-21↓, 1,   other↑, 1,   other↝, 1,   tumCV↓, 6,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↑, 1,   LC3s↑, 1,   TumAuto↓, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   CHK1↑, 1,   DNAdam↑, 2,   DNArepair↓, 1,   DNMT3B↓, 1,   P53↑, 2,   cl‑PARP↑, 8,   PCNA↓, 2,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 2,   CDK2↓, 2,   CDK2↑, 1,   CDK4↓, 2,   CDK4↑, 1,   cycA1/CCNA1↓, 2,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 5,   cycE/CCNE↓, 1,   P21↓, 1,   P21↑, 2,   TumCCA↑, 13,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Diff↑, 1,   ERK↓, 2,   p‑ERK↓, 2,   FGF↓, 1,   GSK‐3β↑, 2,   HDAC↓, 1,   IGF-1↓, 2,   IGFR↓, 1,   mTOR↓, 1,   mTORC1↓, 2,   mTORC2↓, 2,   PI3K↓, 9,   PTEN↑, 1,   RAS↓, 1,   Src↓, 1,   STAT3↓, 3,   p‑STAT3↑, 1,   TumCG↓, 11,   Wnt↓, 2,  

Migration(tgid=13) ⓘ

AP-1↓, 1,   Ca+2↑, 2,   CD11b↑, 1,   E-cadherin↑, 1,   Ki-67↓, 5,   KRAS↓, 1,   miR-22↑, 1,   MMP13↓, 1,   MMP2↓, 3,   MMP7↓, 1,   MMP9↓, 3,   MMPs↓, 1,   Rho↓, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TumCI↓, 3,   TumCMig↓, 4,   TumCP↓, 6,   TumMeta↓, 1,   uPA↓, 3,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 5,   EGFR↓, 3,   Hif1a↓, 1,   NO↑, 1,   VEGF↓, 3,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

cellSen?, 1,   COX2/PTGS2↓, 2,   CXCc↓, 1,   CXCL1↓, 1,   Inflam↓, 1,   JAK1↓, 1,   NF-kB↓, 4,   NK cell↑, 1,   PD-1↝, 1,   TNF-α↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   CDK6↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   ChemoSen↑, 10,   Dose?, 1,   Dose↑, 2,   Dose↝, 24,   Dose∅, 3,   eff?, 1,   eff↓, 2,   eff↑, 10,   eff∅, 1,   Half-Life↓, 1,   RadioS↑, 2,   selectivity↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BloodF↑, 1,   EGFR↓, 3,   HER2/EBBR2↓, 1,   Ki-67↓, 5,   KRAS↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   antiNeop↑, 2,   AntiTum↑, 2,   cardioP↑, 1,   chemoP↑, 3,   chemoPv↑, 3,   fatigue∅, 1,   hepatoP↑, 1,   memory↑, 1,   neuroP↑, 2,   QoL∅, 1,   RenoP↑, 2,   Risk∅, 1,   toxicity↓, 1,   TumVol↓, 3,   TumW↓, 1,  
Total Targets: 186

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

e-ADO↑, 1,   antiCG↝, 1,   Buty↑, 1,   diuretic↑, 1,   GLP-1R↑, 1,   GlyFlow↑, 1,   NeuroI↓, 1,   SCFAs↑, 1,   Stress↓, 4,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 7,   Catalase↑, 1,   GPx↑, 1,   HO-1↑, 1,   lipid-P↓, 1,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 3,   SOD↑, 1,   uricA↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   glucose∅, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   ASK1↓, 1,   Bax:Bcl2↝, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   iNOS↓, 1,   p‑JNK↓, 1,   MAPK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   AntiThr↑, 2,   other↑, 3,   other↝, 5,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   p16↓, 1,   P53↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   PI3K↓, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

cl‑APP↓, 1,   Ca+2↓, 1,   Cartilage↑, 1,   COL1↓, 1,   Fibrosis↓, 1,   MMP1↓, 1,   RAGE↓, 1,   TGF-β1↓, 1,   TJ↑, 1,   α-SMA↓, 1,  

Barriers & Transport(tgid=15) ⓘ

AQPs↑, 1,   BBB↝, 1,   IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   HMGB1↓, 1,   IL1β↓, 2,   IL6↓, 1,   Inflam↓, 9,   JAK2↓, 1,   NF-kB↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

ADAM10↝, 1,   tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 3,   BACE/β-secretase↓, 1,   NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 5,   BioAv↝, 4,   Dose↓, 1,   Dose↑, 1,   Dose↝, 20,   Dose∅, 1,   eff↑, 4,   eff↝, 1,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BloodF↑, 1,   BP↓, 3,   GutMicro↑, 2,   IL6↓, 1,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiAge⇅, 1,   AntiTum↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 4,   memory↑, 3,   neuroP↑, 6,   Pain↓, 1,   radioP↑, 1,   RenoP↑, 1,   Sleep↑, 4,   Strength↑, 1,   toxicity↓, 3,   toxicity↑, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 2,   Bacteria↓, 1,  
Total Targets: 103

Scientific Paper Hit Count for: Dose, Dosage
39 Magnetic Fields
31 Selenium NanoParticles
27 Hydrogen Gas
24 Radiotherapy/Radiation
22 Curcumin
19 Silver-NanoParticles
19 Resveratrol
19 Chemotherapy
17 Vitamin C (Ascorbic Acid)
16 EGCG (Epigallocatechin Gallate)
16 Selenium
16 Selenite (Sodium)
15 Ginkgo biloba-EGb 761
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Chlorogenic acid
12 Carvacrol
12 Ginger/6-Shogaol/Gingerol
12 Inositol
12 Kaempferol
11 buckwheat sprouts
11 Choline
11 Ellagic acid
11 Sulforaphane (mainly Broccoli)
11 Folic Acid, Vit B9
11 Hyperthermia
10 isoquercitrin
10 Lycopene
10 Hydroxycinnamic-acid
10 Lemongrass Extract/Citral
10 Lactoferrin/Talactoferrin
9 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
9 Baicalein
9 Dichloroacetate
9 Exercise
9 itraconazole
9 Magnetic Field Rotating
8 Rutin
8 Auranofin
8 Melatonin
8 Citric Acid
8 Dandelion Root
8 Ferulic acid
8 Fenbendazole
8 Fisetin
8 Fucoidan
8 Ginkgo biloba
8 Ginkgetin
8 HydroxyTyrosol
8 Silymarin (Milk Thistle) silibinin
7 3-bromopyruvate
7 α-Bisabolol / Chamomile oil
7 Quercetin
7 Mung Bean Sprouts
7 Capsaicin
7 Centella asiatica / Gotu kola → asiaticoside
7 chitosan
7 Echinacea
7 Electrical Pulses
7 Formononetin
7 Gamma-aminobutyric acid
7 Genistein (soy isoflavone)
7 Hibiscus sabdariffa
7 Indole-3-carbinol
7 Thymoquinone
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Metformin
6 Aspirin
6 Astaxanthin
6 Vitexin
6 Caffeic acid
6 immunotherapy
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Eugenol
6 Ivermectin
6 Vitamin D3
6 Honokiol
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 iodine
6 Inulin Prebiotic
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Cynara scolymus/Globe Artichoke/Artichoke Extract
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Paclitaxel/Taxol
5 Boron
5 isoorientin
5 Isovitexin
5 Chocolate
5 Spermidine
5 Oxygen, Hyperbaric
5 diet FMD Fasting Mimicking Diet
5 Vitamin B12
5 Gossypol/AT-101
5 Grapeseed extract
5 Isoliquiritigenin
5 Licorice
5 isoflavones
5 Licochalcone A
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 EMF
5 Rosmarinic acid
5 VitK3,menadione
4 cetuximab
4 Cisplatin
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Celastrol
4 Chrysin
4 Chyawanprash
4 Cichoric acid / Chicoric acid
4 Coenzyme Q10
4 HydroxyCitric Acid
4 Garcinol
4 Diclofenac
4 Docosahexaenoic Acid
4 eicosapentaenoic acid
4 Shilajit/Fulvic Acid
4 Gallic acid
4 capecitabine
4 probiotics
4 Propyl gallate
3 Astragalus
3 Fennel Oil/Foeniculum vulgare
3 Angelica archangelica / Garden Angelica
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Beta-Caryophyllene
3 Bromelain
3 borneol
3 Cat’s Claw
3 chaetocin
3 doxorubicin
3 Calorie Restriction Mimetics
3 Crocetin
3 Dasatinib/Phyrago
3 Disulfiram
3 Eurycomanone
3 Silicic Acid
3 Gambogic Acid
3 Huperzine A/Huperzia serrata
3 Isobavachalcone
3 Lapatinib
3 metronomic chemo
3 Methylsulfonylmethane
3 Oleuropein
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Turmerones
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 1,8-Cineole
2 Photodynamic Therapy
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 DTS(dibenzyl trisulphide) from Anamu
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Bortezomib
2 Lecithin
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 Cynaropicrin
2 diet Plant based
2 diet Short Term Fasting
2 D-limonene
2 Emodin
2 5-fluorouracil
2 Evodiamine
2 Vitamin B6,pyridoxine
2 Flickering Light Stimulation
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Germanium inorganic
2 Geraniol
2 Ginkgolide B
2 Gold NanoParticles
2 Germacranolide sesquiterpene lactone
2 Helleborus niger extracts – Christmas Rose
2 Recombinant Methioninase
2 Juglone
2 Potassium
2 L-ornithine
2 Lactobacillus
2 Luteolin
2 nivolumab
2 Iron
2 Niclosamide (Niclocide)
2 Bifidobacterium
2 Phosphatidylserine
2 Rauwolfia serpentina/Indian Snakeroot
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Annona atemoya Leaf Extract
1 Anethole/trans-Anethole
1 Acer okamotoanum
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 brusatol
1 Bruteridin(bergamot juice)
1 Black Seed Oil/Nigella sativa
1 urea
1 Catechins
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Chlorophyllin
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 CUSP9
1 Cysteamine
1 diet Ketogenic
1 Dipyridamole
1 Docetaxel
1 Zinc
1 Protocatechuic acid
1 Estragole
1 Aluminum
1 ferumoxytol
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Arsenic trioxide
1 Vitamin A, Retinoic Acid
1 Bifidobacterium animalis subsp. lactis GCL2505
1 Glabrescione B
1 carboplatin
1 Graviola
1 hydrogen sulfide
1 High-Ozonide Oil
1 Hormone replacement therapy
1 Hyperoside
1 Extracorporeal Shock Wave Therapy
1 Anthocyanins
1 Gemcitabine (Gemzar)
1 lambertianic acid
1 Lapachol
1 Lasiodin
1 MCToil
1 Sulodexide
1 magnetic nanoparticles
1 Mistletoe/Viscum album Extracts
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 ipilimumab
1 Aidi injection
1 Phenolic Acids
1 Polyphenols
1 alpha Linolenic acid
1 Pterostilbene
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 Sinapic acid
1 salinomycin
1 α-Santalol/Sandalwood oil
1 Sulfasalazine
1 irinotecan
1 Terpinen-4-ol / Tea Tree Oil
1 Taurine
1 Triphala
1 triptolide
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vanillic Acid
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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