Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
8109- L-Orn,    Effects of Oral Ingestion of L-Ornithine on Mental Stress and Fatigue Based on the Trier Social Stress Test in Healthy Humans: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial
- Trial, Nor, NA
*cortisol↓, *Stress↓, *Dose↝, *fatigue↓,
8110- L-Orn,    L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism
- Trial, Nor, NA
*Dose↝, *KeyT↝, *FFA/NEFA↝, *NH3↓, *fatigue↓,
8111- L-Orn,    Ornithine and its role in metabolic diseases: An appraisal
- Review, Nor, NA
*other↝, *ODC1↝, *proline↝, *polyA↝, *Cit/L-Cit↝,
8112- LA,    Metabolomics and proteomics reveal the inhibitory effect of Lactobacillus crispatus on cervical cancer
- in-vitro, Cerv, SiHa
HO-1↝, ACSL4↝, Ferroptosis↑, T-cadherin↑, ROS↑, lipid-P↑,
8122- LA,  ProBio,    Probiotics in colorectal cancer: mechanisms, biomarkers, and adjunct strategies
- Review, CRC, NA
GutMicro↑, IBI↑, TumCG↓, Inflam↓, Imm↝, eff↑,
8121- LA,    Exploring Anticancer Potential of Lactobacillus Strains: Insights into Cytotoxicity and Apoptotic Mechanisms on HCT 115 Cancer Cells
- in-vitro, CRC, NA
tumCV↓, BAX↑, Bcl-2↓,
8120- LA,    Lactobacillus Bacteremia and Probiotics: A Review
- Review, Nor, NA
Inf↑, other↝, Sepsis↑, other↝,
8119- LA,    Perioperative synbiotics administration decreases postoperative infections in patients with colorectal cancer: a randomized, double-blind clinical trial
- Trial, CRC, NA
Inf↓, Inf↓,
8117- LA,  ProBio,    The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial
- Trial, CRC, NA
Dose↝, Inf↓, ZO-1↓, other↓,
8116- LA,    Associations of Cervicovaginal Lactobacilli With High-Risk Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia, and Cancer: A Systematic Review and Meta-Analysis
- Review, Cerv, NA
Risk↓,
8115- LA,    Inhibitory Effect of Vaginal Lactobacillus Supernatants on Cervical Cancer Cells
- in-vitro, Cerv, CaSki
TumCP↓, TumCCA↑, E6↓, E7↓, CDK2↓, cycA1/CCNA1↓, P21↑,
8114- LA,    Normal and tumour cervical cells respond differently to vaginal lactobacilli, independent of pH and lactate
- in-vitro, Cerv, HeLa
AntiTum↑, TumCD↑, selectivity↓,
8113- LA,    Analyzing of colorectal cancer related genes and microRNAs expression profiles in response to probiotics Lactobacillus acidophilus and Saccharomyces cerevisiae in colon cancer cell lines
- in-vitro, CRC, HT-29 - in-vitro, CRC, SW480
BAX↑, Casp3↑, Casp9↑, Bcl-2↓, MMP2↓, MMP9↓, miR-34a↑, miR-25-5p↑, miR-195↑, miR-27a-3p↑, Let-7↑, miR-106b↓, miR-17↓, miR-21↓, miR-155↓, miR-221↓, TumPF↓,
8118- LA,  ProBio,    Randomised clinical trial: the effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery - a double-blind study
- Trial, CRC, NA
Inf↓, IBI↑, Dose↝, Diar↓,
1243- LA,    Lactobacilli Modulate Hypoxia-Inducible Factor (HIF)-1 Regulatory Pathway in Triple Negative Breast Cancer Cell Line
- in-vitro, BC, MDA-MB-231
Hif1a↓, HSP90↓, GLUT1↓, VHL↓, SHARP↑,
1272- LA,    Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults
- Trial, Nor, NA
*Pain↓, *other↑,
8146- Lae,    Laetrile treatment for cancer
- Review, Var, NA
AntiCan↝, toxicity↑,
8147- Lae,    Mechanisms underlying the therapeutic effects of Amygdalin in treating Cervical Cancer based on multi-omics analysis
- in-vitro, Cerv, Ca9-22 - in-vitro, Cerv, HeLa
TumCP↓, Apoptosis↑, TumCCA↑, HK2↓, CAIX/CA9↓,
866- Lae,    Amygdalin from Apricot Kernels Induces Apoptosis and Causes Cell Cycle Arrest in Cancer Cells: An Updated Review
- Review, NA, NA
BAX↑, Casp3↑, Bcl-2↓, TumCCA↑,
870- Lae,    Physician Beware: Severe Cyanide Toxicity from Amygdalin Tablets Ingestion
- Case Report, NA, NA
other↑,
869- Lae,    Recent updates and future perspectives about amygdalin as a potential anticancer agent: A review
TumCD↑,
868- Lae,    The Postulated Mechanism of Action of Amygdalin (Vitamin B17) on Cancer Cells
- Review, NA, NA
other∅,
867- Lae,    Effects of the Gut microbiota on Amygdalin and its use as an anti-cancer therapy: Substantial review on the key components involved in altering dose efficacy and toxicity
- Review, NA, NA
other↑,
859- Lae,    Vitamin B17 and its Proposed Application in Treating Cancer
- Analysis, NA, NA
other↑,
860- Lae,    Amygdalin as a Promising Anticancer Agent: Molecular Mechanisms and Future Perspectives for the Development of New Nanoformulations for Its Delivery
- Review, NA, NA
eff↑, Casp3↑, Bcl-2↓,
861- Lae,  Chit,  AgNPs,    Synthesis of polygonal chitosan microcapsules for the delivery of amygdalin loaded silver nanoparticles in breast cancer therapy
other↑,
862- Lae,    Molecular mechanism of amygdalin action in vitro: review of the latest research
- Review, NA, NA
BAX↑, Casp3↑, Bcl-2↓, Akt↓, mTOR↓, p19↑, TumCCA↑, other↓,
863- Lae,    Amygdalin inhibits the growth of renal cell carcinoma cells in vitro
- in-vitro, RCC, NA
TumCG↓, TumCP↓, TumCCA↑, CDK1↓, CycB/CCNB1↓, E-cadherin↝, N-cadherin↝,
864- Lae,    Can Amygdalin Provide any Benefit in Integrative Anticancer Treatment?
- Review, NA, NA
TumCCA↑, COX2/PTGS2↝, E-cadherin↑, other∅, other∅,
865- Lae,    Amygdalin: A Review on Its Characteristics, Antioxidant Potential, Gastrointestinal Microbiota Intervention, Anticancer Therapeutic and Mechanisms, Toxicity, and Encapsulation
*toxicity↝, other↝,
2351- lamb,    Anti-Warburg effect via generation of ROS and inhibition of PKM2/β-catenin mediates apoptosis of lambertianic acid in prostate cancer cells
- in-vitro, Pca, DU145 - in-vitro, Pca, PC3
proCasp3↓, proPARP↓, LDHA↓, Glycolysis↓, HK2↓, PKM2↓, lactateProd↓, p‑STAT3↓, cycD1/CCND1↓, cMyc↓, β-catenin/ZEB1↓, p‑GSK‐3β↓, ROS↑, eff↓, Warburg↓,
8155- lamb,    Ethanol extract of Pinus koraiensis leaves containing lambertianic acid exerts anti-obesity and hypolipidemic effects by activating adenosine monophosphate-activated protein kinase (AMPK)
- vitro+vivo, Nor, 3T3
*p‑AMPK↑, *PPARγ↓, *CEBPA↓, *adiP↓, *Fas↓, *SREBP1/SREBF1↓, *HMGCR↓, *lipidLev↓, *TG/TAG↓, *Weight↓, *LDL↓, *Obesity↓,
8154- lamb,    Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells
- in-vitro, Nor, NA
*IL6↓, *PGD2↓, *LTC4↓, *COX2/PTGS2↓, *β-HEX↓, *antiAll↑,
8152- lamb,  TRAIL/rTRAIL,    Lambertianic Acid Sensitizes Non-Small Cell Lung Cancers to TRAIL-Induced Apoptosis via Inhibition of XIAP/NF-κB and Activation of Caspases and Death Receptor 4
- in-vitro, NSCLC, A549 - in-vitro, Lung, H1299
TumCD↑, cl‑PARP↑, Casp3↑, Casp8↑, Casp9↑, Bcl-2↓, cFLIP↓, XIAP↓, BID↑, DR4↑, p‑NF-kB↓, p‑IκB↓,
8158- lamb,    Effect of Pinus koraiensis leaf extract on fatigue reduction and exercise performance: study protocol for a randomized, double-blind, placebo-controlled clinical trial
- Trial, Nor, NA
*Strength↑, *lactateProd↓, *LDH↓, *CK2↓,
8151- lamb,    Suppression of STAT3 Phosphorylation and RelA/p65 Acetylation Mediated by MicroRNA134 Plays a Pivotal Role in the Apoptotic Effect of Lambertianic Acid
- in-vitro, BC, MCF7 - in-vitro, Pca, DU145 - in-vitro, Pca, PC3 - in-vitro, BC, MDA-MB-231
TumCCA↑, cl‑PARP↑, p‑STAT3↓, NF-kB↓, XIAP?, survivin↓, Bcl-2↓, Bcl-xL↓, VEGF↓, COX2/PTGS2↓, cMyc↓, IL6↓, TNF-α↓, ac‑p65↑, Obesity↓, miR-134↑,
8150- lamb,    Reactive oxygen species dependent phosphorylation of the liver kinase B1/AMP activated protein kinase/ acetyl-CoA carboxylase signaling is critically involved in apoptotic effect of lambertianic acid in hepatocellular carcinoma cells
- in-vitro, HCC, HepG2 - in-vitro, HCC, SK-HEP-1
lipidLev↓, TumCCA↑, cl‑Casp3↑, cl‑PARP↑, AMPK↑, Akt↓, mTOR↓, Bcl-2↓, Bcl-xL↓, COX2/PTGS2↓, ROS↑, eff↓, p‑STK11/LKB1↑, p‑ACC↑, *Obesity↓, *Stress↓, *antiAll↑, tumCV↓, selectivity↑, TumCP↓,
8149- lamb,    Apoptotic effect of lambertianic acid through AMPK/FOXM1 signaling in MDA-MB231 breast cancer cells
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
TumCD↑, TumCCA↑, AMPK↑, Akt↓, FOXM1↓, Bcl-2↓, CycB/CCNB1↓, APOE4↑,
8148- lamb,    Anti-Cancer Effect of Lambertianic Acid by Inhibiting the AR in LNCaP Cells
- in-vitro, Pca, LNCaP
*antiAll↑, *Bacteria↓, AR↓, PSA↓, TumCCA↑, CDK4↓, CDK6↓, cycD1/CCND1↓, P53↑, P21↑, p27/CDKN1B↓, Apoptosis↑, cl‑Casp9↑, cl‑Casp3↑, cl‑PARP↑, BAX↑, Bcl-2↓, Dose↝,
8156- lamb,    A review on chemistry, source and therapeutic potential of lambertianic acid
- Review, Var, NA
*Obesity↓, *AntiCan↑, *AMPK↑, *β-HEX↓, NA↑, TumCCA↑, AMPK↑, ACC↑, p‑Akt↓, FOXM1↓, CycB/CCNB1↓, XIAP↓, Bcl-2↓, p‑STAT3↓, p‑NF-kB↓, Bcl-xL↓, survivin↓, VEGF↓, COX2/PTGS2↓, cMyc↓, IL6↓, TNF-α↓, ROS↑, STK11/LKB1↑, cl‑Casp3↑, cl‑PARP↑, eff↑, AR↓, TumCP↓, p‑P53↓, P21↓, p27/CDKN1B↓, cycD1/CCND1↓, CDK4↓, PSA↓, STAT3↓, ac‑p65↓, *antiAll↑,
8157- lamb,    Pinus koraiensis leaf extract and lambertianic acid attenuate fatigue and improve endurance capacity via PI3K-mediated regulation of oxidative stress and mitochondrial biogenesis
- in-vivo, Nor, NA
*fatigue↓, *ROS↓, *NF-kB↓, *IL6↓, *SOD↑, *PI3K↑, *NRF2↑, *HO-1↑, *SIRT1↑, *PGC-1α↑, *Nrf1↑, *Strength↑,
8174- Lap,    Lapatinib: a dual inhibitor of human epidermal growth factor receptor tyrosine kinases
EGFR↓, HER2/EBBR2↓, BioAv↝, eff↑, Dose↝,
8173- Lap,  Tras,    Efficacy and safety of lapatinib and trastuzumab for HER2-positive breast cancer: a systematic review and meta-analysis of randomised controlled trials
- Review, BC, NA
CR↑, EFS↑, OS↑, toxicity↝,
8172- Lap,    Administration of Lapatinib with Food Increases Its Plasma Concentration in Chinese Patients with Metastatic Breast Cancer: A Prospective Phase II Study
- Trial, BC, NA
BioAv↑, eff↑,
8171- Lap,    Effects of food on the relative bioavailability of lapatinib in cancer patients
- Trial, Var, NA
BioAv↝, Dose↝,
8170- Lap,  capec,    A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses
- Trial, BC, NA
Dose↝, TTP↑, OS↑,
8169- Lap,    Lapatinib Activates the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in HepG2 Cells
- in-vitro, Liver, HepG2
toxicity↑, mtDam↑, ROS↑, NRF2↑, GSH↑, GSSG↑, SOD2↑,
8167- LapC,    Characterization of lapachol cytotoxicity: contribution of glutathione depletion for oxidative stress in Saccharomyces cerevisiae
- in-vitro, Nor, NA
*GSH↓, *SOD1↓, *lipid-P↑, *ROS↑,
8160- LapC,    Crystallographic Structure of Human Dihydroorotate Dehydrogenase in Complex with the Natural Product Inhibitor Lapachol
- Study, NA, NA
DHODH↓,
8161- LapC,    Lapachol is a novel ribosomal protein S6 kinase 2 inhibitor that suppresses growth and induces intrinsic apoptosis in esophageal squamous cell carcinoma cells
- in-vitro, ESCC, KYSE-30 - in-vitro, ESCC, KYSE450 - in-vitro, ESCC, KYSE-510
RSK2/RPS6KA3/p90RSK2↓, TumCG↓, Apoptosis↑, Casp3↑, Casp7↑, PARP↑, Cyt‑c↑, BAX↑, p‑CREB↓, ATF1↓, H3↓, CycB/CCNB1↓, cycD1/CCND1↓, p‑CDK2↓,

Showing Research Papers: 5301 to 5350 of 8269
Prev Page 107 of 166 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8269

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

APOE4↑, 1,   ATF1↓, 1,   CR↑, 1,   DHODH↓, 1,   EFS↑, 1,   miR-106b↓, 1,   miR-134↑, 1,   miR-195↑, 1,   NA↑, 1,   RSK2/RPS6KA3/p90RSK2↓, 1,   TTP↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Ferroptosis↑, 1,   GSH↑, 1,   GSSG↑, 1,   HO-1↝, 1,   lipid-P↑, 1,   NRF2↑, 1,   ROS↑, 5,   SOD2↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

mtDam↑, 1,   XIAP?, 1,   XIAP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↑, 1,   p‑ACC↑, 1,   ACSL4↝, 1,   AMPK↑, 3,   CAIX/CA9↓, 1,   cMyc↓, 3,   p‑CREB↓, 1,   Glycolysis↓, 1,   HK2↓, 2,   lactateProd↓, 1,   LDHA↓, 1,   lipidLev↓, 1,   PKM2↓, 1,   SHARP↑, 1,   STK11/LKB1↑, 1,   p‑STK11/LKB1↑, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   p‑Akt↓, 1,   Apoptosis↑, 3,   BAX↑, 6,   Bcl-2↓, 11,   Bcl-xL↓, 3,   BID↑, 1,   Casp3↑, 6,   cl‑Casp3↑, 3,   proCasp3↓, 1,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 2,   cl‑Casp9↑, 1,   cFLIP↓, 1,   Cyt‑c↑, 1,   DR4↑, 1,   Ferroptosis↑, 1,   p27/CDKN1B↓, 2,   survivin↓, 2,   TumCD↑, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,   miR-25-5p↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

H3↓, 1,   miR-21↓, 1,   miR-27a-3p↑, 1,   other↓, 2,   other↑, 4,   other↝, 3,   other∅, 3,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP90↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,   p‑P53↓, 1,   PARP↑, 1,   cl‑PARP↑, 5,   proPARP↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 1,   p‑CDK2↓, 1,   CDK4↓, 2,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 4,   cycD1/CCND1↓, 4,   p19↑, 1,   P21↓, 1,   P21↑, 2,   TumCCA↑, 11,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

FOXM1↓, 2,   p‑GSK‐3β↓, 1,   Let-7↑, 1,   miR-34a↑, 1,   mTOR↓, 2,   STAT3↓, 1,   p‑STAT3↓, 3,   TumCG↓, 3,  

Migration(tgid=13) ⓘ

E-cadherin↑, 1,   E-cadherin↝, 1,   miR-155↓, 1,   miR-221↓, 1,   MMP2↓, 1,   MMP9↓, 1,   N-cadherin↝, 1,   T-cadherin↑, 1,   TumCP↓, 5,   TumPF↓, 1,   ZO-1↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

EGFR↓, 1,   Hif1a↓, 1,   miR-17↓, 1,   VEGF↓, 2,   VHL↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   IBI↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 3,   COX2/PTGS2↝, 1,   IL6↓, 2,   Imm↝, 1,   Inflam↓, 1,   p‑IκB↓, 1,   NF-kB↓, 1,   p‑NF-kB↓, 2,   ac‑p65↓, 1,   ac‑p65↑, 1,   PSA↓, 2,   TNF-α↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 2,   CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   BioAv↝, 2,   Dose↝, 6,   eff↓, 2,   eff↑, 5,   selectivity↓, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 2,   E6↓, 1,   E7↓, 1,   EGFR↓, 1,   FOXM1↓, 2,   GutMicro↑, 1,   HER2/EBBR2↓, 1,   IL6↓, 2,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↝, 1,   AntiTum↑, 1,   Obesity↓, 1,   OS↑, 2,   Risk↓, 1,   toxicity↑, 2,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

Diar↓, 1,   Inf↓, 4,   Inf↑, 1,   Sepsis↑, 1,  
Total Targets: 155

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

antiAll↑, 4,   Cit/L-Cit↝, 1,   FFA/NEFA↝, 1,   LTC4↓, 1,   ODC1↝, 1,   Stress↓, 2,   β-HEX↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

GSH↓, 1,   HO-1↑, 1,   lipid-P↑, 1,   Nrf1↑, 1,   NRF2↑, 1,   ROS↓, 1,   ROS↑, 1,   SOD↑, 1,   SOD1↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

adiP↓, 1,   AMPK↑, 1,   p‑AMPK↑, 1,   KeyT↝, 1,   lactateProd↓, 1,   LDH↓, 1,   LDL↓, 1,   lipidLev↓, 1,   NH3↓, 1,   polyA↝, 1,   PPARγ↓, 1,   SIRT1↑, 1,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5) ⓘ

CK2↓, 1,   Fas↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,   other↝, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,   HMGCR↓, 1,   PI3K↑, 1,  

Migration(tgid=13) ⓘ

proline↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IL6↓, 2,   NF-kB↓, 1,   PGD2↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

cortisol↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 2,  

Clinical Biomarkers(tgid=22) ⓘ

IL6↓, 2,   LDH↓, 1,   TG/TAG↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   fatigue↓, 3,   Obesity↓, 3,   Pain↓, 1,   Strength↑, 2,   toxicity↝, 1,   Weight↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,  
Total Targets: 55

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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