Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
Source:
Type:
Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
4446- SeNPs,    Antioxidant and Hepatoprotective Effects of Moringa oleifera-mediated Selenium Nanoparticles in Diabetic Rats.
- in-vivo, Diabetic, NA
*glucose↓, *antiOx↑, *GPx↑, *Catalase↑, *SOD↑, *ROS↓, *cardioP↑, *HDL↑, *LDL↓, *hepatoP↑, *TNF-α↓, *IL6↓, *IL1β↓, *lipid-P↓, *Inflam↓, *ALAT↓, *AST↓, *ALP↓, *Dose↝, *Dose↝,
4461- SeNPs,  VitC,    Synthesis, Characterization, and Cytotoxic Evaluation of Selenium Nanoparticles
*Dose?,
4457- SeNPs,    Selenium nanoparticles: a review on synthesis and biomedical applications
- Review, Var, NA - NA, Diabetic, NA
*BioAv↑, *toxicity↓, *eff↑, chemoPv↑, *Inflam↓, antiOx↑, *selenoP↑, *ROS↓, *Dose↝, AntiCan↑, *Bacteria↓, eff↑, DNAdam↑, selectivity↑, *eff↑,
4458- SeNPs,    Selenium Nanoparticles for Antioxidant Activity and Selenium Enrichment in Plants
*Dose↝, *eff↑, *Dose↝,
4460- SeNPs,  VitC,    Ascorbic acid-mediated selenium nanoparticles as potential antihyperuricemic, antioxidant, anticoagulant, and thrombolytic agents
Dose?,
2164- SFN,  dietP,    Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice
- in-vitro, Pca, NA
HDAC↓, Dose↝, Risk↓, TumCP↓, H3↓,
2406- SFN,    Sulforaphane and Its Protective Role in Prostate Cancer: A Mechanistic Approach
- Review, Pca, NA
HK2↓, PKM2↓, LDHA↓, Glycolysis↓, LAMP2↑, Hif1a↓, DNAdam↓, DNArepair↓, Dose↝,
2552- SFN,  Chemo,    Chemopreventive activity of sulforaphane
- Review, Var, NA
chemoPv↑, TumCG↓, *ROS↓, *Inflam↓, *Dose↝, *NRF2↑, *HO-1↑, *NQO1↑, NF-kB↓, ROS↑,
2554- SFN,    Sulforaphane (SFN): An Isothiocyanate in a Cancer Chemoprevention Paradigm
- Review, Var, NA
Dose↝, chemoPv↑, *NQO1↑, *GSTA1↑, HDAC↓, NF-kB↓,
2448- SFN,    Sulforaphane and bladder cancer: a potential novel antitumor compound
- Review, Bladder, NA
Apoptosis↑, TumCG↓, TumCI↓, TumMeta↓, glucoNG↓, ChemoSen↑, TumCCA↑, Casp3↑, Casp7↑, cl‑PARP↑, survivin↓, EGFR↓, HER2/EBBR2↓, ATP↓, Glycolysis↓, mt-OXPHOS↓, AKT1↓, HK2↓, Hif1a↓, ROS↑, NRF2↑, EMT↓, COX2↓, MMP2↓, MMP9↓, Zeb1↓, Snail↓, HDAC↓, HATs↓, MMP↓, Cyt‑c↓, Shh↓, Smo↓, Gli1↓, BioAv↝, BioAv↝, Dose↝,
1726- SFN,    Sulforaphane: A Broccoli Bioactive Phytocompound with Cancer Preventive Potential
- Review, Var, NA
Dose↝, eff↝, IL1β↓, IL6↓, IL12↓, TNF-α↓, COX2↓, CXCR4↓, MPO↓, HSP70/HSPA5↓, HSP90↓, VCAM-1↓, IKKα↓, NF-kB↓, HO-1↑, Casp3↑, Casp7↑, Casp8↑, Casp9↑, cl‑PARP↑, Cyt‑c↑, Diablo↑, CHOP↑, survivin↓, XIAP↓, p38↑, Fas↑, PUMA↑, VEGF↓, Hif1a↓, Twist↓, Zeb1↓, Vim↓, MMP2↓, MMP9↓, E-cadherin↑, N-cadherin↓, Snail↓, CD44↓, cycD1/CCND1↓, cycA1/CCNA1↓, CycB/CCNB1↓, cycE/CCNE↓, CDK4↓, CDK6↓, p50↓, P53↑, P21↑, GSH↑, SOD↑, GSTs↑, mTOR↓, Akt↓, PI3K↓, β-catenin/ZEB1↓, IGF-1↓, cMyc↓, CSCs↓,
1725- SFN,    Anticancer Activity of Sulforaphane: The Epigenetic Mechanisms and the Nrf2 Signaling Pathway
- Review, Var, NA
*toxicity∅, AntiCan↑, antiOx↑, NRF2↑, DNMTs↓, HDAC↓, Hif1a↓, VEGF↓, P21↑, TumCCA↑, ac‑H3↑, ac‑H4↑, DNAdam↑, Dose↝,
1507- SFN,    Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
- in-vivo, Colon, NA - Human, Nor, NA
TumCG↓, HDAC↓, *BioAv↑, Dose∅, Half-Life∅,
1501- SFN,    The Inhibitory Effect of Sulforaphane on Bladder Cancer Cell Depends on GSH Depletion-Induced by Nrf2 Translocation
- in-vitro, CRC, T24/HTB-9
Dose↝, NRF2↑, GSH↓, eff↑,
3321- SIL,    Silymarin (Milk thistle)
- Review, AD, NA
*neuroP↝, *Dose↝, *Half-Life?, *BioAv↝, *cognitive↑, *Aβ↓, *Inflam↓, *OS↑, *memory↑,
3314- SIL,    Silymarin: Unveiling its pharmacological spectrum and therapeutic potential in liver diseases—A comprehensive narrative review
- Review, NA, NA
*antiOx↑, *hepatoP↑, *Half-Life↑, *ROS↓, *GSH↑, *hepatoP↑, *lipid-P↓, *TNF-α↓, *IFN-γ↓, *IL2↓, *IL4↓, *NF-kB↓, *iNOS↓, *OATPs↓, *OCT4↓, *Inflam↓, *PGE2↓, MMPs↓, VEGF↓, angioG↓, STAT3↓, *ALAT↓, *AST↓, Dose↝,
3305- SIL,    Silymarin inhibits proliferation of human breast cancer cells via regulation of the MAPK signaling pathway and induction of apoptosis
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF-7 - in-vivo, NA, NA
TumCP↓, tumCV↓, BAX↑, cl‑PARP↑, Casp9↑, p‑JNK↑, Bcl-2↓, p‑p38↓, p‑ERK↓, *toxicity∅, Dose↝, *hepatoP↑, Inflam↓, AntiCan↑,
3309- SIL,    Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives
- Review, NA, NA
*ROS↓, *IronCh↑, *MMP↑, *NRF2↑, *Inflam↓, *hepatoP↑, *HSPs↑, *Trx↑, *SIRT2↑, *GSH↑, *ROS↑, *NADPH↓, *iNOS↓, *NF-kB↓, *BioAv↓, *Dose↝, *BioAv↑,
3293- SIL,    Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer
- Review, Var, NA
hepatoP↑, TumMeta↓, Inflam↓, chemoP↑, radioP↑, Half-Life↝, *GSTs↑, p‑JNK↑, BAX↑, p‑p38↑, cl‑PARP↑, Bcl-2↓, p‑ERK↓, TumVol↓, eff↑, TumCCA↑, STAT3↓, Mcl-1↓, survivin↓, Bcl-xL↓, Casp3↑, Casp9↑, eff↑, CXCR4↓, Dose↝,
3282- SIL,    Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions
- Review, NA, NA
hepatoP↑, AntiCan↑, TumCMig↓, Hif1a↓, selectivity↑, toxicity∅, *antiOx↑, *Inflam↓, TumCCA↑, P21↑, CDK4↓, NF-kB↓, ERK↓, PSA↓, TumCG↓, p27↑, COX2↓, IL1↓, VEGF↓, IGFBP3↑, AR↓, STAT3↓, Telomerase↓, Cyt‑c↑, Casp↑, eff↝, HDAC↓, HATs↑, Zeb1↓, E-cadherin↑, miR-203↑, NHE1↓, MMP2↓, MMP9↓, PGE2↓, Vim↓, Wnt↓, angioG↓, VEGF↓, *TIMP1↓, EMT↓, TGF-β↓, CD44↓, EGFR↓, PDGF↓, *IL8↓, SREBP1↓, MMP↓, ATP↓, uPA↓, PD-L1↓, NOTCH↓, *SIRT1↑, SIRT1↓, CA↓, Ca+2↑, chemoP↑, cardioP↑, Dose↝, Half-Life↝, BioAv↓, BioAv↓, BioAv↓, toxicity↝, Half-Life↓, ROS↓, FAK↓,
2306- SIL,  CUR,  RES,  EA,    Identification of Natural Compounds as Inhibitors of Pyruvate Kinase M2 for Cancer Treatment
- in-vitro, BC, MDA-MB-231
PKM2↓, Dose↝, Dose↝,
4133- Silicon,    Relation between aluminum concentrations in drinking water and Alzheimer's disease: an 8-year follow-up study
- Study, AD, NA
*Risk↓, *Dose↑, *neuroP↑,
4128- Silicon,    Silicon as Versatile Player in Plant and Human Biology: Overlooked and Poorly Understood
- Review, NA, NA
*other↑, *BMD↑, *Dose↝, *cognitive↑, *Dose?,
2361- SK,    Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer
- in-vivo, CRC, NA
GutMicro↑, Dose↝, IL1β↓, IL6↓, TNF-α↓, PKM2↓,
2218- SK,    Shikonin Alleviates Endothelial Cell Injury Induced by ox-LDL via AMPK/Nrf2/HO-1 Signaling Pathway
- in-vitro, Nor, HUVECs
*Dose↝, *Apoptosis↓, *Casp3↓, *Bcl-2↑, *Inflam↓, *VCAM-1↓, *ICAM-1↓, *E-sel↓, *ROS↓, *SOD↑, *AMPK↑, *NRF2↑, *HO-1↑, *TNF-α↓, *IL1β↓, *IL6↓,
2007- SK,    Shikonin Directly Targets Mitochondria and Causes Mitochondrial Dysfunction in Cancer Cells
- in-vitro, lymphoma, U937 - in-vitro, BC, MCF-7 - in-vitro, BC, SkBr3 - in-vitro, CRC, HCT116 - in-vitro, OS, U2OS - NA, Nor, RPE-1
tumCV↓, selectivity↑, Dose↝, other↑, MMP↓, ROS↑, DNAdam↑, Ca+2↑, Casp9↑, Cyt‑c↑, *toxicity↓,
4895- Sper,    Spermidine as a target for cancer therapy
- Review, Var, NA - Review, AD, NA
TumAuto↑, Apoptosis↑, OS↑, CRM↑, TumCG⇅, cardioP↑, cognitive↑, *Dose⇅,
5789- Sper,    Long-term oral polyamine intake increases blood polyamine concentrations
- Human, Nor, NA
*Dose↝, *BioAv↑,
5805- Sper,    The Effect of Spermidine Supplementation on Cognitive Function in Adults: A Mini-Review
- Review, AD, NA
*cognitive↝, *Dose↝,
5799- Sper,    The positive effect of spermidine in older adults suffering from dementia : First results of a 3-month trial
- Trial, AD, NA
*cognitive↑, memory↑, *Dose↑, *Dose↑, *Dose↝, *Dose↝, BioAv↓, eff↑,
1697- SSE,  Calc,    Calcium intake may explain the reduction of colorectal cancer odds by dietary selenium - a case-control study in Poland
- Human, CRC, NA
Risk↓, Risk↓, Dose∅, AntiCan↑,
1688- SSE,    Potential Role of Selenium in the Treatment of Cancer and Viral Infections
- Review, Var, NA
IL2↑, INF-γ↑, Th1 response↑, Th2↑, Dose↑, AntiCan∅, Risk↑, chemoP↑, Hif1a↓, VEGF↓, selectivity↑, *GADD45A↑, NRF2↓, *NRF2↑, ChemoSen↑, angioG↓, PrxI↓, ChemoSideEff↓, eff↑,
4739- SSE,  Chemo,  Rad,    Therapeutic Benefits of Selenium in Hematological Malignancies
- Review, Var, NA
ChemoSen↑, radioP↑, QoL↑, Risk↓, *selenoP↑, TumCP↓, Inflam↓, ChemoSen↑, TumCCA↑, Apoptosis↑, angioG↓, Dose⇅, ROS↑, eff↑, Risk↓, eff∅, CSCs↓, ROS↑,
4748- SSE,  Chemo,  antiOx,    Efficacy and safety of intravenous administration of high-dose selenium for preventing chemotherapy-induced peripheral neuropathy in gastric cancer patients receiving adjuvant oxaliplatin and capecitabine after gastrectomy: a retrospective pilot study
- Trial, GC, NA
toxicity↓, chemoP∅, *neuroP↑, *Dose↝,
4742- SSE,    Antitumor Effects of Selenium
- Review, Var, NA - Review, Arthritis, NA - Review, Sepsis, NA
*antiOx↓, *Inflam↓, Risk↓, TumCI↓, TumMeta↓, radioP↑, chemoP↑, Apoptosis↑, ROS↑, DNAdam↑, Dose↑, selectivity↑, *other↓, *BioAv↑, ROS↑, MMP↓, Casp↑, *Imm↑, *Pain↓, Sepsis↓, MMP2↓, MMP9↓, *Half-Life↓,
4740- SSE,    Optimising Selenium for Modulation of Cancer Treatments
- Review, Var, NA
*selenoP↑, *Dose↓, Risk↓, *toxicity↝, Dose↑, chemoP↑, radioP↑,
4716- SSE,    Selenium Substitution During Radiotherapy of Solid Tumours – Laboratory Data from Two Observation Studies in Gynaecological and Head and Neck Cancer Patients
- in-vivo, HNSCC, NA
Dose↝, *GPx↑, *ROS↓,
4718- SSE,    High-Dose Selenium Induces Ferroptotic Cell Death in Ovarian Cancer
- in-vitro, Ovarian, NA
TumCP↑, ROS↑, GPx↓, lipid-P↑, Ferroptosis↑, Dose↑,
5081- SSE,    Application Notes and Protocols: Selenite as a Selenium Source in Cell Culture Media Supplementation
- Review, Var, NA
Dose↝, ROS↑, Akt↓, mTOR↓, TumCCA↑, Apoptosis↑,
5078- SSE,  Rad,    Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer
- Trial, Pca, NA
Half-Life↝, OS↑, Pain↓, PSA↓, GSH↓, ROS↑, selectivity↑, TumCG↓, AR↓, Dose↑, ChemoSen↑, RadioS↑,
5074- SSE,    Application of Sodium Selenite in the Prevention and Treatment of Cancers
- Review, Var, NA
Imm↑, angioG↑, DNArepair↑, NK cell↑, ROS↑, AntiCan↑, selectivity↑, ER Stress↑, TumAuto↑, necrosis↑, toxicity↝, Dose↑,
5073- SSE,    Pharmacokinetics and Toxicity of Sodium Selenite in the Treatment of Patients with Carcinoma in a Phase I Clinical Trial: The SECAR Study
- Trial, Var, NA
AntiTum↑, ChemoSen↑, Dose↑, Half-Life↝, toxicity↝, toxicity↝,
5093- SSE,    Pharmacological mechanisms of the anticancer action of sodium selenite against peritoneal cancer in mice
- in-vivo, Var, NA
AntiCan↑, eff↑, selectivity↑, ROS↑, Dose↝, Trx↓, GSH↓,
4498- SSE,    Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases
- Review, Var, NA - Review, AD, NA - Review, IBD, NA
*Imm↑, *GutMicro↑, *BioAv↑, *Risk↓, *Dose↝, Risk↓, *CRP↓, *GPx↓, *Inflam↓, *selenoP↑, *Dose↝, *ROS↓, *MDA↓, *SOD↑, *GPx↑, *IL1↓, *MCP1↓, *IL6↓, *TNF-α↓, Risk↓, *neuroP↑, *memory↑,
4614- SSE,  Rad,    Updates on clinical studies of selenium supplementation in radiotherapy
- Review, Nor, NA
*toxicity∅, Risk↓, *selenoP↑, *ROS↓, *DNAdam↓, *QoL↑, *radioP↑, *Dose↝,
3952- Taur,    Taurine and Astrocytes: A Homeostatic and Neuroprotective Relationship
- Review, AD, NA - Review, Stroke, NA
*antiOx↑, *Inflam↓, *Ca+2↓, *neuroP↑, *other↑, *Dose↝, *PKCδ↓, *VGCC↓, *GABA↑,
5331- TFdiG,    Anti-Cancer Properties of Theaflavins
- Review, Var, NA
AntiCan↑, TumCP↓, TumCMig↓, Apoptosis↑, cl‑PARP↑, cl‑Casp3↑, cl‑Casp7↑, cl‑Casp8↑, cl‑Casp9↑, BAX↑, Bcl-2↓, p‑Akt↓, p‑mTOR↓, PI3K↓, cMyc↓, P53↑, ROS↑, NF-kB↓, MMP9↓, MMP2↓, TumVol↓, PSA↓, TumCCA↑, VEGF↓, Hif1a↓, CDK2↓, CDK4↓, GSH↓, Dose↑, BioAv↓, BioAv↓, BioAv↑,
5332- TFdiG,    Theaflavin-3,3′-digallate triggers apoptosis in osteosarcoma cells via the caspase pathway
- vitro+vivo, OS, 143B - in-vitro, OS, U2OS
tumCV↓, cl‑Casp3↑, cl‑Casp9↑, p‑γH2AX↑, BAX↑, Bak↑, Cyt‑c↑, Mcl-1↓, survivin↓, TumVol↓, Wnt↓, β-catenin/ZEB1↓, Dose↝, ROS↑, eff↓, TumW↓, Ki-67↓,
5333- TFdiG,    Theaflavin-3,3′-Digallate Plays a ROS-Mediated Dual Role in Ferroptosis and Apoptosis via the MAPK Pathway in Human Osteosarcoma Cell Lines and Xenografts
- vitro+vivo, OS, MG63
tumCV↓, TumCP↓, TumCCA↑, Iron↑, ROS↑, GSH↓, Fenton↑, Ferroptosis↑, Apoptosis↑, MAPK↑, ERK↑, JNK↑, p38↑, TumCG↓, Dose↝, FTH1↓, GPx4↓,
4565- TQ,    Thymoquinone in the clinical treatment of cancer: Fact or fiction?
- Review, BC, NA
Dose↝, TumCCA↑, P21↑, cycD1/CCND1↓, TumCI↑, TumMeta↓, Bcl-2↓, Bcl-xL↓, survivin↓, PTEN↑, Akt↓, P53↑, NF-kB↓, cardioP↑, Dose↝,

Showing Research Papers: 501 to 550 of 587
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 587

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   Fenton↑, 1,   Ferroptosis↑, 2,   GPx↓, 1,   GPx4↓, 1,   GSH↓, 5,   GSH↑, 1,   GSTs↑, 1,   HO-1↑, 1,   Iron↑, 1,   lipid-P↑, 1,   MPO↓, 1,   NRF2↓, 1,   NRF2↑, 3,   mt-OXPHOS↓, 1,   PrxI↓, 1,   ROS↓, 1,   ROS↑, 15,   SOD↑, 1,   Trx↓, 1,  

Metal & Cofactor Biology ⓘ

FTH1↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 2,   MMP↓, 4,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

AKT1↓, 1,   cMyc↓, 2,   CRM↑, 1,   glucoNG↓, 1,   Glycolysis↓, 2,   HK2↓, 2,   LDHA↓, 1,   PKM2↓, 3,   SIRT1↓, 1,   SREBP1↓, 1,  

Cell Death ⓘ

Akt↓, 3,   p‑Akt↓, 1,   Apoptosis↑, 7,   Bak↑, 1,   BAX↑, 4,   Bcl-2↓, 4,   Bcl-xL↓, 2,   Casp↑, 2,   Casp3↑, 3,   cl‑Casp3↑, 2,   Casp7↑, 2,   cl‑Casp7↑, 1,   Casp8↑, 1,   cl‑Casp8↑, 1,   Casp9↑, 4,   cl‑Casp9↑, 2,   Cyt‑c↓, 1,   Cyt‑c↑, 4,   Diablo↑, 1,   Fas↑, 1,   Ferroptosis↑, 2,   JNK↑, 1,   p‑JNK↑, 2,   MAPK↑, 1,   Mcl-1↓, 2,   necrosis↑, 1,   p27↑, 1,   p38↑, 2,   p‑p38↓, 1,   p‑p38↑, 1,   PUMA↑, 1,   survivin↓, 5,   Telomerase↓, 1,  

Kinase & Signal Transduction ⓘ

HER2/EBBR2↓, 1,  

Transcription & Epigenetics ⓘ

H3↓, 1,   ac‑H3↑, 1,   ac‑H4↑, 1,   HATs↓, 1,   HATs↑, 1,   other↑, 1,   tumCV↓, 4,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   ER Stress↑, 1,   HSP70/HSPA5↓, 1,   HSP90↓, 1,  

Autophagy & Lysosomes ⓘ

LAMP2↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,   DNAdam↑, 4,   DNArepair↓, 1,   DNArepair↑, 1,   DNMTs↓, 1,   P53↑, 3,   cl‑PARP↑, 5,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 3,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   P21↑, 4,   TumCCA↑, 9,  

Proliferation, Differentiation & Cell State ⓘ

CD44↓, 2,   CSCs↓, 2,   EMT↓, 2,   ERK↓, 1,   ERK↑, 1,   p‑ERK↓, 2,   Gli1↓, 1,   HDAC↓, 6,   IGF-1↓, 1,   IGFBP3↑, 1,   mTOR↓, 2,   p‑mTOR↓, 1,   NOTCH↓, 1,   PI3K↓, 2,   PTEN↑, 1,   Shh↓, 1,   Smo↓, 1,   STAT3↓, 3,   TumCG↓, 6,   TumCG⇅, 1,   Wnt↓, 2,  

Migration ⓘ

CA↓, 1,   Ca+2↑, 2,   E-cadherin↑, 2,   FAK↓, 1,   Ki-67↓, 1,   miR-203↑, 1,   MMP2↓, 5,   MMP9↓, 5,   MMPs↓, 1,   N-cadherin↓, 1,   PDGF↓, 1,   Snail↓, 2,   TGF-β↓, 1,   TumCI↓, 2,   TumCI↑, 1,   TumCMig↓, 2,   TumCP↓, 5,   TumCP↑, 1,   TumMeta↓, 4,   Twist↓, 1,   uPA↓, 1,   VCAM-1↓, 1,   Vim↓, 2,   Zeb1↓, 3,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature ⓘ

angioG↓, 4,   angioG↑, 1,   EGFR↓, 2,   Hif1a↓, 7,   VEGF↓, 7,  

Barriers & Transport ⓘ

NHE1↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 3,   CXCR4↓, 2,   IKKα↓, 1,   IL1↓, 1,   IL12↓, 1,   IL1β↓, 2,   IL2↑, 1,   IL6↓, 2,   Imm↑, 1,   INF-γ↑, 1,   Inflam↓, 3,   NF-kB↓, 6,   NK cell↑, 1,   p50↓, 1,   PD-L1↓, 1,   PGE2↓, 1,   PSA↓, 3,   Th1 response↑, 1,   Th2↑, 1,   TNF-α↓, 2,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 2,   CDK6↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 6,   BioAv↑, 1,   BioAv↝, 2,   ChemoSen↑, 6,   Dose?, 1,   Dose↑, 8,   Dose⇅, 1,   Dose↝, 22,   Dose∅, 2,   eff↓, 1,   eff↑, 8,   eff↝, 2,   eff∅, 1,   Half-Life↓, 1,   Half-Life↝, 4,   Half-Life∅, 1,   RadioS↑, 1,   selectivity↑, 8,  

Clinical Biomarkers ⓘ

AR↓, 2,   EGFR↓, 2,   GutMicro↑, 1,   HER2/EBBR2↓, 1,   IL6↓, 2,   Ki-67↓, 1,   PD-L1↓, 1,   PSA↓, 3,  

Functional Outcomes ⓘ

AntiCan↑, 8,   AntiCan∅, 1,   AntiTum↑, 1,   cardioP↑, 3,   chemoP↑, 5,   chemoP∅, 1,   chemoPv↑, 3,   ChemoSideEff↓, 1,   cognitive↑, 1,   hepatoP↑, 2,   memory↑, 1,   OS↑, 2,   Pain↓, 1,   QoL↑, 1,   radioP↑, 4,   Risk↓, 10,   Risk↑, 1,   toxicity↓, 1,   toxicity↝, 4,   toxicity∅, 1,   TumVol↓, 3,   TumW↓, 1,  

Infection & Microbiome ⓘ

Sepsis↓, 1,  
Total Targets: 220

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 4,   Catalase↑, 1,   GPx↓, 1,   GPx↑, 3,   GSH↑, 2,   GSTA1↑, 1,   GSTs↑, 1,   HDL↑, 1,   HO-1↑, 2,   lipid-P↓, 2,   MDA↓, 1,   NQO1↑, 2,   NRF2↑, 4,   ROS↓, 9,   ROS↑, 1,   selenoP↑, 5,   SOD↑, 3,   Trx↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 2,   AMPK↑, 1,   glucose↓, 1,   LDL↓, 1,   NADPH↓, 1,   SIRT1↑, 1,   SIRT2↑, 1,  

Cell Death ⓘ

Apoptosis↓, 1,   Bcl-2↑, 1,   Casp3↓, 1,   iNOS↓, 2,  

Transcription & Epigenetics ⓘ

other↓, 1,   other↑, 2,  

Protein Folding & ER Stress ⓘ

HSPs↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,   GADD45A↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

OCT4↓, 1,   VGCC↓, 1,  

Migration ⓘ

Ca+2↓, 1,   E-sel↓, 1,   PKCδ↓, 1,   TIMP1↓, 1,   VCAM-1↓, 1,  

Barriers & Transport ⓘ

OATPs↓, 1,  

Immune & Inflammatory Signaling ⓘ

CRP↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 1,   IL1↓, 1,   IL1β↓, 2,   IL2↓, 1,   IL4↓, 1,   IL6↓, 3,   IL8↓, 1,   Imm↑, 2,   Inflam↓, 11,   MCP1↓, 1,   NF-kB↓, 2,   PGE2↓, 1,   TNF-α↓, 4,  

Synaptic & Neurotransmission ⓘ

GABA↑, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 6,   BioAv↝, 1,   Dose?, 2,   Dose↓, 1,   Dose↑, 3,   Dose⇅, 1,   Dose↝, 19,   eff↑, 3,   Half-Life?, 1,   Half-Life↓, 1,   Half-Life↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 2,   ALP↓, 1,   AST↓, 2,   BMD↑, 1,   CRP↓, 1,   GutMicro↑, 1,   IL6↓, 3,  

Functional Outcomes ⓘ

cardioP↑, 1,   cognitive↑, 3,   cognitive↝, 1,   hepatoP↑, 5,   memory↑, 2,   neuroP↑, 4,   neuroP↝, 1,   OS↑, 1,   Pain↓, 1,   QoL↑, 1,   radioP↑, 1,   Risk↓, 2,   toxicity↓, 2,   toxicity↝, 1,   toxicity∅, 3,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 97

Scientific Paper Hit Count for: Dose, Dosage
31 Selenium NanoParticles
30 Magnetic Fields
21 Curcumin
19 Resveratrol
18 Silver-NanoParticles
17 Vitamin C (Ascorbic Acid)
16 Selenium
16 Selenite (Sodium)
15 Radiotherapy/Radiation
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Hydrogen Gas
12 Chemotherapy
12 Carvacrol
12 Chlorogenic acid
11 EGCG (Epigallocatechin Gallate)
11 Choline
10 Sulforaphane (mainly Broccoli)
9 Baicalein
8 Auranofin
8 Lycopene
8 Magnetic Field Rotating
7 3-bromopyruvate
7 Capsaicin
7 chitosan
7 Citric Acid
7 Ellagic acid
7 Electrical Pulses
7 Exercise
7 Silymarin (Milk Thistle) silibinin
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Astaxanthin
6 Melatonin
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Dichloroacetate
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Metformin
5 Aspirin -acetylsalicylic acid
5 Boron
5 Spermidine
5 Hydroxycinnamic-acid
5 diet FMD Fasting Mimicking Diet
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 Rosmarinic acid
5 Vitamin D3
5 VitK3,menadione
4 cetuximab
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Caffeic acid
4 Celastrol
4 immunotherapy
4 Chocolate
4 Coenzyme Q10
4 Oxygen, Hyperbaric
4 Shilajit/Fulvic Acid
4 Propyl gallate
4 Thymoquinone
3 Astragalus
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Bromelain
3 borneol
3 Cat’s Claw
3 Chrysin
3 Calorie Restriction Mimetics
3 HydroxyCitric Acid
3 Disulfiram
3 Fisetin
3 Honokiol
3 metronomic chemo
3 Methylsulfonylmethane
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Paclitaxel
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 doxorubicin
2 Garcinol
2 diet Plant based
2 diet Short Term Fasting
2 Folic Acid, Vit B9
2 Gambogic Acid
2 Potassium
2 Luteolin
2 capecitabine
2 Iron
2 Niclosamide (Niclocide)
2 probiotics
2 Bifidobacterium
2 Silicic Acid
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Cisplatin
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 Bortezomib
1 brusatol
1 Bruteridin(bergamot juice)
1 urea
1 Catechins
1 Cannabidiol
1 Chlorophyllin
1 Camptothecin
1 Crocetin
1 CUSP9
1 diet Ketogenic
1 Docetaxel
1 Zinc
1 Emodin
1 Ferulic acid
1 Fenbendazole
1 Gallic acid
1 Ginkgo biloba
1 Ginger/6-Shogaol/Gingerol
1 Huperzine A/Huperzia serrata
1 itraconazole
1 Juglone
1 MCToil
1 nivolumab
1 magnetic nanoparticles
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 Oleuropein
1 Hyperthermia
1 Phosphatidylserine
1 Pterostilbene
1 Quercetin
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 salinomycin
1 Sulfasalazine
1 irinotecan
1 Taurine
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vitamin B6,pyridoxine
1 Vitamin B12
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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