BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
Scientific Papers found: Click to Expand⟱
7781- ISL,    Perspectives on the Role of Isoliquiritigenin in Cancer
- Review, Var, NA
*BioAv↝, *BBB↓, *BioAv↑, selectivity↑, *neuroP↑, *Inflam↓, NF-kB↓, TNF-α↓, IL6↓, IL1β↓, IL10↓, ICAM-1↓, COX2/PTGS2↓, PPARγ↑, MMP2↓, cFos↓, VEGF↓, CHOP/DDIT3↓, CTSK↓, CycB/CCNB1↑, cycD1/CCND1↑, TOP2↑, PI3K↓, Akt↓, mTOR↓, MMP9↓, TIMP1↓, ChemoSen↑, CSCs↓,
7785- ISL,    Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System
- in-vivo, Nor, NA
*Dose↝, *BioAv↑, *uricA↓, *XO↓,
7735- isoFl,    Soy Isoflavones in Integrative Oncology: Increased Efficacy and Decreased Toxicity of Cancer Therapy
- Review, Var, NA
Risk↓, ChemoSen↑, chemoP↑, RadioS↑, radioP↑, NF-kB↓, DNMTs↓, TumMeta↓, angioG↓, antiOx↑, BioAv↑, toxicity↓,
7732- isoFl,    Biological activities and therapeutic potential of soy isoflavones: a focus on anticancer activity
*Inflam↓, *ROS↓, Apoptosis↑, NOS2↑, *Aβ↓, *BioAv↓, *BioAv↑, *BioAv↝, *neuroP↑, *BBB↑, TNF-α↓, ROS↑, selectivity↑, ChemoSen↑, eff↝,
7860- isoO,    Metabolism and plasma pharmacokinetics of isoorientin, a natural active ingredient, in Sprague-Dawley male rats after oral and intravenous administration
Half-Life↝, BioAv↓,
7877- isoO,    Isoorientin: A dietary flavone with the potential to ameliorate diverse metabolic complications
- Review, Nor, NA
*antiOx↑, *Inflam↓, *ROS↓, *Inflam↓, *BioAv↓,
7795- ISQ,    The Flavonol Isoquercitrin Promotes Mitochondrial-Dependent Apoptosis in SK-Mel-2 Melanoma Cell via the PI3K/AKT/mTOR Pathway
- in-vitro, Melanoma, SK-MEL-28 - in-vitro, Nor, HaCaT
BioAv↑, TumCP↓, selectivity↑, DNAdam↑, Apoptosis↑, TumCCA↑, Bcl-2↓, cl‑PARP↑, BAX↑, AIF↑, Endoglin↑, PI3K↓, Akt↓, mTOR↓,
7849- ISQ,  QC,    Isoquercitrin provides better bioavailability than quercetin: comparison of quercetin metabolites in body tissue and brain sections after six days administration of isoquercitrin and quercetin
- in-vivo, Nor, NA
*Dose↝, *BioAv↑,
7791- ISQ,    Isoquercitrin: pharmacology, toxicology, and metabolism
- Review, Nor, NA
*BioAv↑, *chemoP↑, *ROS↓, *cardioP↑, *AntiDiabetic↑, *Dose↝,
7841- ISQ,    Enzymatically modified isoquercitrin improves endothelial function in volunteers at risk of cardiovascular disease
- Human, CardioV, NA
*Risk↓, *BioAv↑, *Dose↝, *eff↑,
7846- ISQ,    Ninety-day toxicity and single-dose toxicokinetics study of alpha-glycosyl isoquercitrin in Sprague-Dawley rats
- in-vivo, Nor, NA
*BioAv↑, *toxicity↓,
7848- ISQ,    Review of anticancer mechanisms of isoquercitin
- Review, Var, NA
BioAv↑, eff↑, *antiOx↓, TumCP↓, *Inflam↓, *AntiDiabetic↑, lipid-P↓, *toxicity↓, *Half-Life↝, *Half-Life↑, *XO↝, *IronCh↝, *VitC↑, *ROS↓, β-catenin/ZEB1↓, Casp3↑, Casp8↑, Casp9↑, MMP↓, p‑ERK↓, p‑cJun↑,
7559- ISQ,    Difference in absorption of the two structurally similar flavonoid glycosides, hyperoside and isoquercitrin, in rats
- in-vivo, Nor, NA
*Dose↝, *BioAv↑,
7989- itraC,    Concentration-dependent Early Antivascular and Antitumor Effects of Itraconazole in Non-Small Cell Lung Cancer
- Trial, NSCLC, NA
Dose↝, TumVol↓, angioG↓, IL1β↓, GM-CSF↓, HH∅, BioAv↝, other↝,
2180- itraC,    Repurposing Drugs in Oncology (ReDO)—itraconazole as an anti-cancer agent
- Review, Var, NA
Dose↝, toxicity↝, BioAv↑, Half-Life↝, BioAv↑, Dose↝, HH↓, TumAuto↑, Akt↓, mTOR↓, angioG↓, MDR1↓, TumCP↓, eff↑,
8028- IVM,    Ivermectin as an Alternative Anticancer Agent: A Review of Its Chemical Properties and Therapeutic Potential
- Review, Var, NA
*BioAv↝, Apoptosis↑, TumCP↓, Wnt↓, β-catenin/ZEB1↓, TumCG↓, TumMeta↓, PI3K↓, Akt↓, mTOR↓, TumPF↓, CSCs↓, eff↑, ChemoSen↑, mtDam↑, MMP↓, ATP↓, ROS↑, NF-kB↓, BAX↑, Casp3↑, Casp9↑, ICD↑, Ki-67↓, PSA↓, YAP/TEAD↓,
8044- IVM,    Current therapeutic applications and pharmacokinetic modulations of ivermectin
- Review, Var, NA
*AntiP↑, BioAv↓,
7917- IVT,    A review on the pharmacological effects of vitexin and isovitexin
- Review, Nor, NA - Review, AD, NA
*antiOx↑, *AntiCan↑, *Inflam↓, *neuroP↑, *AChE↓, *BChE↓, *BACE/β-secretase↓, *Stroke↓, *AntiAg↓, *AntiDiabetic↑, *AGEs↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *Obesity↓, *BioAv↝, *BioAv↓,
7898- IVT,    Pharmacokinetics and tissue distribution study of Isovitexin in rats by HPLC-MS/MS
- in-vivo, Nor, NA
*Dose↝, *Half-Life↝, *BioAv↝,
7900- IVT,    Isovitexin: A Promising Active Compound Found in Nature's Bounty
- in-vivo, Nor, NA
*BioAv↓, *Imm↝, *antiOx↑, *AntiCan↑, *neuroP↑, *hepatoP↑, *Inflam↓, *NF-kB↓, *MAPK↓, *MPO↓, *ROS↓, TumAuto↑, Apoptosis↑,
8085- KAE,    Effects and Mechanisms of Kaempferol in the Management of Cancers through Modulation of Inflammation and Signal Transduction Pathways
- Review, Var, NA
Apoptosis↑, TumCCA↑, angioG↓, PI3K↓, Akt↓, STAT3↓, AP-1↓, NRF2↓, BioAv↑, Inflam↓, NF-kB↓, TNF-α↓, VEGF↓, BAX↑, Casp↑, Bcl-2↓, P53↑, PTEN↑, hTERT/TERT↓, NRF2↓, ROS↑, DR5↑, ERK↑, CHOP/DDIT3↑, DR4↑, JNK↑, Ki-67↓, ChemoSen↑,
8086- KAE,    Hepatoprotective Effect of Kaempferol: A Review of the Dietary Sources, Bioavailability, Mechanisms of Action, and Safety
- Review, Nor, NA
*hepatoP↑, *BioAv↝, *CYP2E1↓, *antiOx↑, *AST↓, *ALAT↓, *ROS↓, *lipid-P↓, *SIRT1↑, *GSH↑, *SOD↑, *p‑SMAD2↓, *p‑SMAD3↓, *COL1↓, *other↝,
8087- KAE,    Therapeutic Importance of Kaempferol in the Treatment of Cancer through the Modulation of Cell Signalling Pathways
- Review, Var, NA
TumCCA↓, ROS↝, Apoptosis↑, TumCP↑, TumMeta↓, angioG↓, PI3K↓, EMT↓, Snail↓, E-cadherin↓, N-cadherin↓, MMP2↓, Casp9↑, Casp7↑, PARP↑, Apoptosis↑, *ROS↓, Hif1a↓, p‑Akt↓, P53↑, cMyc↓, Glycolysis↓, PKM2↓, miR-339-5p↝, BioAv↓,
8088- KAE,    Kaempferol: Antimicrobial Properties, Sources, Clinical, and Traditional Applications
- Review, Nor, NA
*AntiCan↓, *Inflam↓, *Bacteria↓, *AntiFungal↑, *BioAv↝,
8090- KAE,    A systematic review of anti-cancer roles and mechanisms of kaempferol as a natural compound
- Review, Nor, NA
*cardioP↑, *AntiCan↑, *Inflam↓, *neuroP↑, *BioAv↓, selectivity?, p‑Akt↓, p‑cycD1/CCND1↓, p‑CDK4↓, p‑BID↓, p‑Mcl-1↓, p‑BRCA1↑, ATM↑, P53↑, P21↑, p38↑, BAX↑, BID↑, MMP↓, Casp3↑, Casp7↑, Casp9↑, AIF↑, ER Stress↑, TumMeta↓, ERK↓, AP-1↓, JNK↓, p38↓, GLUT1↓, GlucoseCon↓, MMP9↓, CYP1A1↓, ChemoSen↑, OCT4↓, Nanog↓, P-gp/ABCB1↓, ALDH1A1↓, TumCCA↑, DNAdam↑, γH2AX↑, COX2/PTGS2↓, i-ROS↓, Ca+2↓, eff↑, DR5↑, ChemoSen↑, Akt↓, PI3K↓, ROS↑, EMT↓, survivin↓,
8095- KAE,    Kaempferol: A Key Emphasis to Its Anticancer Potential
- Review, Var, NA
*AntiBio↑, *Inflam↓, *AntiTum↓, *antiOx↑, *cardioP↑, *neuroP↑, *AntiDiabetic↑, Risk↓, TumCCA↑, EMT↓, PI3K↓, Akt↓, MMP2↓, Casp3↑, Casp7↑, Casp9↑, PARP↑, *ROS↓, angioG↓, *BioAv↑, BioAv↑, selectivity↑, GLUT1↓, MCT1↓, ROS↓, ROS↑, Trx↓, Cyt‑c↑, MMP↓, miR-21↓, SOCS-3↓, STAT3↓, CDK1↓, CycB/CCNB1↑, HIF-1↓, JAK1↑, PTEN↑,
8071- KAE,    Cellular reprogramming and signaling control by kaempferol in colorectal cancer
- Review, CRC, NA
*toxicity↓, Risk↓, MMPs↓, VEGF↓, VEGFR1↓, Wnt↓, β-catenin/ZEB1↑, PI3K↓, Akt↓, mTOR↓, ChemoSen↑, *BioAv↓, TumCCA↑, Apoptosis↑, Hif1a↓, ROS↑, TumCMig↓, TumMeta↓, PKM2↓, Glycolysis↓, DNAdam↑, HO-1↑, Ferroptosis↑, eff↑, Dose↝, BioAv↑,
8072- KAE,    Natural defense against colorectal cancer: the effects of kaempferol on epigenetics, apoptosis, inflammation, oxidative stress, and cell proliferation
- Review, CRC, NA
AntiCan↑, TumCP↓, TumCI↓, Inflam↓, angioG↓, ROS↑, Apoptosis↑, ChemoSen↑, Risk↓, *antiOx↑, *Inflam↓, *AntiBio↑, *cardioP↑, *neuroP↑, selectivity↑, PUMA↑, Cyt‑c↑, cl‑Casp3↑, cl‑PARP↑, Apoptosis↑, NF-kB↓, COX2/PTGS2↓, CC(CDKs/cyclins)↓, TumCCA↑, BioAv↓, eff↑, DR4↑, DR5↑, Casp3↑, Casp9↑, Casp7↑, TumCP↓, TumCI↓, TumAuto↑, mtDam↑, P53↑, MAPK↑, *lipid-P↓, *TAC↑, *Catalase↑, *SOD↑, *GPx↑, *NRF2↑,
8080- KAE,    Hepatoprotective Effect of Kaempferol—A Review
- Review, Nor, NA
*hepatoP↑, *SIRT1↑, *AMPK↑, *TLR4↓, *NF-kB↓, *GutMicro↑, *Dose↝, *BioAv↓, *BioAv↑, *CYP2E1↓, *lipidLev↓, *COX2/PTGS2↓, *IL1β↓, *TNF-α↓, *IL6↓, *NO↓, *PGE2↓, *iNOS↓, *SOD↑, *MDA↓, *ROS↓, *AST↓, *ALAT↓, *GSH↑, *SOD↑, *Cyt‑c↓, *BAX↓, *Casp3↓, *Casp8↓, *Casp9↓, *COL1↓, *p‑SMAD2↓, *p‑SMAD3↑, *α-SMA↓, *TGF-β↓, *P450↝, *P-gp/ABCB1↓, *BioEnh↑,
8081- KAE,    The Anticancer Effects and Therapeutic Potential of Kaempferol in Triple-Negative Breast Cancer
- Review, BC, NA
*antiOx↓, *Inflam↓, *neuroP↓, *AntiCan↑, DNAdam↓, Casp3↑, Casp9↑, p‑AMT/GCST/T-protein↑, ROS↑, NRF2↑, Apoptosis↑, cl‑PARP↓, BAX↑, Bcl-2↓, TumCCA↓, angioG↓, MMP3↓, MMP9↓, ChemoSen↑, BioAv↓, Glycolysis↓, cl‑PARP↑, Ca+2↑, MMP↓, ER Stress↑, GRP78/BiP↑, CHOP/DDIT3↑, ATF6↑, angioG↓, VEGF↓, Hif1a↓, chemoP↑, *ROS↓, NRF2↑, BioAv↑,
8056- KAE,    Kaempferol: advances in biosynthesis, molecular mechanisms, and therapeutic applications
- Review, Var, NA - Review, Diabetic, NA
*antiOx↑, *ROS↓, *NRF2↑, *Inflam↓, *NF-kB↓, *MAPK↓, *STAT↓, *AntiDiabetic↑, *AMPK↑, *IRes↑, Apoptosis↑, TumCCA↑, TumMeta↓, PI3K↓, Akt↓, Wnt↓, β-catenin/ZEB1↓, *AntiBio↑, *hepatoP↑, *SIRT1↝, *BioAv↓,
8057- KAE,    Absorption of kaempferol from endive, a source of kaempferol-3-glucuronide, in humans
- Human, Nor, NA
*BioAv↝, *BioAv↓, *BioAv↝,
8174- Lap,    Lapatinib: a dual inhibitor of human epidermal growth factor receptor tyrosine kinases
EGFR↓, HER2/EBBR2↓, BioAv↝, eff↑, Dose↝,
8172- Lap,    Administration of Lapatinib with Food Increases Its Plasma Concentration in Chinese Patients with Metastatic Breast Cancer: A Prospective Phase II Study
- Trial, BC, NA
BioAv↑, eff↑,
8171- Lap,    Effects of food on the relative bioavailability of lapatinib in cancer patients
- Trial, Var, NA
BioAv↝, Dose↝,
8163- LapC,    Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis
- in-vivo, Arthritis, NA
*DHODH↓, *Imm↓, AntiArt↑, antiPs↑, BioAv↝,
8166- LapC,    Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model
- vitro+vivo, BC, NA
BioAv↓, *toxicity↑, eff↑,
8215- LCA,    Determination of licochalcone A in rat plasma by UPLC–MS/MS and its pharmacokinetics
- in-vivo, Nor, NA
*BioAv↓,
8218- LCA,    Advances in Pharmacological Activities and Drug Delivery Systems of Licochalcone A
- Review, Nor, NA
*Inflam↓, *antiOx↑, *AntiTum↑, *hepatoP↑, *Bacteria↓, AntiCan↑, BioAv↓, BioAv↑,
8219- LCA,    Licochalcone A Ameliorates Cognitive Dysfunction in an Alzheimer's Disease Model by Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis
- in-vivo, AD, NA
*Dose↝, *cognitive↑, *Aβ↓, *ER Stress↓, *BioAv↑, *toxicity↓, *PERK↓, *eIF2α↓, *ATF4↓, *CHOP/DDIT3↓, *NRF2↑,
8240- LE,    Licorice flavonoids nanoparticles prepared by liquid antisolvent re-crystallization exhibit higher oral bioavailability and antioxidant activity in rat
- in-vivo, Nor, NA
*BioAv↑,
1794- LEC,    Effects of abomasal infusion of soybean or sunflower lecithin on nutrient digestibility and milk production in lactating dairy cows
- in-vivo, NA, NA
BioAv↑, other↑,
1795- LEC,  Chit,    Self-assembled lecithin-chitosan nanoparticles improve the oral bioavailability and alter the pharmacokinetics of raloxifene
- in-vivo, Nor, NA
eff↑, BioAv↑,
1796- LEC,    A comprehensive review on pleiotropic effects and therapeutic potential of soy lecithin
- Review, NA, NA
BioAv↑, antiOx↑, LDL↓, memory↑,
8145- LF,    Neuroprotective Effects of Lactoferrin in Alzheimer's and Parkinson's Diseases: A Narrative Review
- Review, AD, NA - Review, Park, NA
*AntiBio↑, *Imm↑, *AntiCan↑, *neuroP↑, *BBB↑, *APOE4↓, *ROS↓, *Inflam↓, *Apoptosis↓, *Learn↑, *memory↑, *ADAM10↑, *PSEN1/PS1↑, *cl‑APP↑, *BACE/β-secretase↓, *cognitive↑, *MDA↓, *IL6↓, *TNF-α↓, *neuroP↑, *Dose↝, *IronCh↑, *SOD↑, *BioAv↝,
8136- LF,    Oral fate and stabilization technologies of lactoferrin: a systematic review
- Review, Nor, NA
*BioAv↓, *BioAv↓,
8135- LF,    Lactoferrin-A Regulator of Iron Homeostasis and Its Implications in Cancer
- Review, Var, NA - Review, AD, NA
IronCh↑, ROS↓, Imm↑, Inflam↓, *BBB↑, Iron↝, *Fenton↓, *ROS↓, *TAC↑, *SOD↑, *GPx↑, *GSH↑, *TBARS↓, *PTEN↓, *tau↓, *MAPK↓, *Aβ42↓, *Apoptosis↓, *Casp3↓, *Akt↑, *GutMicro↑, *Sepsis↓, *anemia↓, *IL6↓, *FPN↑, *TfR1/CD71↑, *Ferritin↓, *HemoG↑, *RBC↑, *eff↑, *BioAv↓, *BioAv↑, *BioAv↝, *ChemoSen↑, *BioAv↑, Ferroptosis↑,
8137- LF,    Lactoferrin delivery systems: approaches for its more effective use
- Review, IBD, NA
*Imm↑, *BioAv↓, *BioAv↑,
8200- LGE,    Chemical Properties and Therapeutic Potential of Citral, a Monoterpene Isolated from Lemongrass
- Review, Var, NA
*AntiBio↑, *antiOx↑, *AntiCan↑, *AntiDiabetic↑, *Inflam↓, Dose↝, BioAv↝,
8193- LGE,    Targets and pathways involved in the antitumor activity of citral and its stereo-isomers
- Review, Var, NA
TumCP↓, Apoptosis↑, ROS↑, DNAdam↑, MARK4↓, ALDH1A3↓, CSCs↓, chemoR↓, BioAv↓, selectivity↝,

Showing Research Papers: 501 to 550 of 780
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 780

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

ALDH1A3↓, 1,   p‑AMT/GCST/T-protein↑, 1,   AntiArt↑, 1,   CTSK↓, 1,   miR-339-5p↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   CYP1A1↓, 1,   Ferroptosis↑, 2,   HO-1↑, 1,   ICD↑, 1,   Iron↝, 1,   lipid-P↓, 1,   NRF2↓, 2,   NRF2↑, 2,   ROS↓, 2,   ROS↑, 9,   ROS↝, 1,   i-ROS↓, 1,   Trx↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 2,   ATP↓, 1,   MMP↓, 5,   mtDam↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 3,   LDL↓, 1,   PKM2↓, 2,   PPARγ↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 9,   p‑Akt↓, 2,   Apoptosis↑, 13,   BAX↑, 5,   Bcl-2↓, 3,   BID↑, 1,   p‑BID↓, 1,   Casp↑, 1,   Casp3↑, 6,   cl‑Casp3↑, 1,   Casp7↑, 4,   Casp8↑, 1,   Casp9↑, 7,   Cyt‑c↑, 2,   DR4↑, 2,   DR5↑, 3,   Ferroptosis↑, 2,   hTERT/TERT↓, 1,   JNK↓, 1,   JNK↑, 1,   MAPK↑, 1,   p‑Mcl-1↓, 1,   MCT1↓, 1,   p38↓, 1,   p38↑, 1,   PUMA↑, 1,   survivin↓, 1,   YAP/TEAD↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

p‑cJun↑, 1,   miR-21↓, 1,   other↑, 1,   other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 2,   ER Stress↑, 2,   GRP78/BiP↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   p‑BRCA1↑, 1,   DNAdam↓, 1,   DNAdam↑, 4,   DNMTs↓, 1,   P53↑, 4,   PARP↑, 2,   cl‑PARP↓, 1,   cl‑PARP↑, 3,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   p‑CDK4↓, 1,   CycB/CCNB1↑, 2,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   P21↑, 1,   TumCCA↓, 2,   TumCCA↑, 7,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH1A1↓, 1,   cFos↓, 1,   CSCs↓, 3,   EMT↓, 3,   ERK↓, 1,   ERK↑, 1,   p‑ERK↓, 1,   HH↓, 1,   HH∅, 1,   mTOR↓, 5,   Nanog↓, 1,   OCT4↓, 1,   PI3K↓, 9,   PTEN↑, 2,   STAT3↓, 2,   TOP2↑, 1,   TumCG↓, 1,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AP-1↓, 2,   Ca+2↓, 1,   Ca+2↑, 1,   CC(CDKs/cyclins)↓, 1,   E-cadherin↓, 1,   Ki-67↓, 2,   MARK4↓, 1,   MMP2↓, 3,   MMP3↓, 1,   MMP9↓, 3,   MMPs↓, 1,   N-cadherin↓, 1,   Snail↓, 1,   TIMP1↓, 1,   TumCI↓, 2,   TumCMig↓, 1,   TumCP↓, 7,   TumCP↑, 1,   TumMeta↓, 6,   TumPF↓, 1,   VEGFR1↓, 1,   β-catenin/ZEB1↓, 3,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 9,   EGFR↓, 1,   Endoglin↑, 1,   HIF-1↓, 1,   Hif1a↓, 3,   VEGF↓, 4,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 2,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 3,   GM-CSF↓, 1,   ICAM-1↓, 1,   IL10↓, 1,   IL1β↓, 2,   IL6↓, 1,   Imm↑, 1,   Inflam↓, 3,   JAK1↑, 1,   NF-kB↓, 5,   PSA↓, 1,   SOCS-3↓, 1,   TNF-α↓, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 8,   BioAv↑, 14,   BioAv↝, 5,   chemoR↓, 1,   ChemoSen↑, 10,   Dose↝, 7,   eff↑, 10,   eff↝, 1,   Half-Life↝, 2,   MDR1↓, 1,   RadioS↑, 1,   selectivity?, 1,   selectivity↑, 5,   selectivity↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

p‑BRCA1↑, 1,   EGFR↓, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 1,   IL6↓, 1,   Ki-67↓, 2,   NOS2↑, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   antiPs↑, 1,   chemoP↑, 2,   memory↑, 1,   radioP↑, 1,   Risk↓, 4,   toxicity↓, 1,   toxicity↝, 1,   TumVol↓, 1,  
Total Targets: 180

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

anemia↓, 1,   AntiBio↑, 5,   AntiP↑, 1,   APOE4↓, 1,   Aβ42↓, 1,   DHODH↓, 1,   FPN↑, 1,   IRes↑, 1,   Learn↑, 1,   PSEN1/PS1↑, 1,   RBC↑, 1,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 9,   Catalase↑, 1,   CYP2E1↓, 2,   Fenton↓, 1,   GPx↑, 2,   GSH↑, 3,   lipid-P↓, 2,   MDA↓, 2,   MPO↓, 1,   NRF2↑, 3,   ROS↓, 13,   SOD↑, 6,   TAC↑, 2,   TBARS↓, 1,   uricA↓, 1,   VitC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 1,   IronCh↝, 1,   TfR1/CD71↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   AMPK↑, 2,   lipidLev↓, 1,   SIRT1↑, 2,   SIRT1↝, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Apoptosis↓, 2,   BAX↓, 1,   Casp3↓, 2,   Casp8↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   iNOS↓, 1,   MAPK↓, 3,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   eIF2α↓, 1,   ER Stress↓, 1,   PERK↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

PTEN↓, 1,   STAT↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   cl‑APP↑, 1,   COL1↓, 2,   p‑SMAD2↓, 2,   p‑SMAD3↓, 1,   p‑SMAD3↑, 1,   TGF-β↓, 1,   α-SMA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↓, 1,   NO↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 3,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IL1β↓, 2,   IL6↓, 4,   IL8↓, 1,   Imm↓, 1,   Imm↑, 2,   Imm↝, 1,   Inflam↓, 16,   NF-kB↓, 3,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   ADAM10↑, 1,   BChE↓, 1,   tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   Aβ↓, 2,   BACE/β-secretase↓, 2,   XO↓, 1,   XO↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 14,   BioAv↑, 15,   BioAv↝, 11,   BioEnh↑, 1,   ChemoSen↑, 1,   Dose↝, 9,   eff↑, 2,   Half-Life↑, 1,   Half-Life↝, 2,   P450↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 2,   Ferritin↓, 1,   GutMicro↑, 2,   HemoG↑, 1,   IL6↓, 4,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↓, 1,   AntiCan↑, 6,   AntiDiabetic↑, 6,   AntiTum↓, 1,   AntiTum↑, 1,   cardioP↑, 4,   chemoP↑, 1,   cognitive↑, 2,   hepatoP↑, 5,   memory↑, 1,   neuroP↓, 1,   neuroP↑, 9,   Obesity↓, 1,   Risk↓, 1,   toxicity↓, 4,   toxicity↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   Bacteria↓, 2,   Sepsis↓, 1,  
Total Targets: 123

Scientific Paper Hit Count for: BioAv, bioavailability
49 Curcumin
21 EGCG (Epigallocatechin Gallate)
20 chitosan
19 Quercetin
18 Baicalein
18 Chlorogenic acid
17 Resveratrol
16 Selenium NanoParticles
16 Sulforaphane (mainly Broccoli)
15 Apigenin (mainly Parsley)
15 Berberine
15 Chrysin
14 Pterostilbene
13 Kaempferol
13 Thymoquinone
11 Silymarin (Milk Thistle) silibinin
11 Honokiol
11 Lycopene
10 Alpha-Lipoic-Acid
10 Carvacrol
10 Rosmarinic acid
9 Astaxanthin
9 borneol
8 Capsaicin
8 Crocetin
8 Emodin
8 Ferulic acid
8 Fucoidan
8 Piperlongumine
8 Urolithin
7 Allicin (mainly Garlic)
7 Artemisinin
7 Betulinic acid
7 Hydroxycinnamic-acid
7 Piperine
7 Fisetin
7 HydroxyTyrosol
7 Isoliquiritigenin
7 isoquercitrin
7 Luteolin
7 Phenethyl isothiocyanate
6 Silver-NanoParticles
6 Ashwagandha(Withaferin A)
6 Biochanin A
6 Rutin
6 Thymol-Thymus vulgaris
6 Propolis -bee glue
6 Ellagic acid
6 Eugenol
5 beta-glucans
5 Baicalin
5 Boswellia (frankincense)
5 Centella asiatica / Gotu kola → asiaticoside
5 Cucurbitacin
5 Formononetin
5 Gallic acid
5 Inositol
5 Magnolol
5 Naringin
5 Selenite (Sodium)
4 1,8-Cineole
4 5-Hydroxytryptophan
4 Beta-Caryophyllene
4 Boron
4 Caffeic acid
4 Celastrol
4 Garcinol
4 Isovitexin
4 Lactoferrin/Talactoferrin
4 Phenylbutyrate
4 Vitamin C (Ascorbic Acid)
4 Shikonin
4 Aflavin-3,3′-digallate
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Berbamine
3 Folic Acid, Vit B9
3 Chocolate
3 Cinnamon
3 Coenzyme Q10
3 Copper and Cu NanoParticles
3 Diclofenac
3 Disulfiram
3 Fenbendazole
3 Gambogic Acid
3 Genistein (soy isoflavone)
3 Glabrescione B
3 Gossypol/AT-101
3 Grapeseed extract
3 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
3 Lapatinib
3 Licochalcone A
3 Lecithin
3 Magnetic Fields
3 Niclosamide (Niclocide)
3 Selenium
3 Silicic Acid
3 Spermidine
3 Terpinen-4-ol / Tea Tree Oil
2 3-bromopyruvate
2 Auranofin
2 Astragalus
2 Citric Acid
2 Chemotherapy
2 Aspirin
2 Paclitaxel/Taxol
2 Atorvastatin
2 immunotherapy
2 Radiotherapy/Radiation
2 buckwheat sprouts
2 Butyrate
2 Melatonin
2 Cynanbungeigenin C (CBC) and D (CBD)
2 Chlorophyllin
2 Choline
2 Camptothecin
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Dasatinib/Phyrago
2 Dichloroacetate
2 Deguelin
2 D-limonene
2 Evodiamine
2 flavonoids
2 Shilajit/Fulvic Acid
2 Geraniol
2 Ginkgolide B
2 Ginkgetin
2 Hydrogen Gas
2 HydroxyCitric Acid
2 isoflavones
2 isoorientin
2 itraconazole
2 Ivermectin
2 Lapachol
2 Lemongrass Extract/Citral
2 Methyl salicylate / Sweet Birch oil
2 magnetic nanoparticles
2 nicotinamide adenine dinucleotide
2 Oleuropein
2 Turmerones
2 Ursolic acid
1 Aluminum
1 Anethole/trans-Anethole
1 Aromatherapy
1 Gemcitabine (Gemzar)
1 Aloe anthraquinones
1 doxorubicin
1 Docetaxel
1 xanthohumol
1 beta-carotene(VitA)
1 Bicalutamide
1 Bacopa monnieri
1 α-Bisabolol / Chamomile oil
1 Bullatacin
1 Carnosic acid
1 urea
1 capecitabine
1 Catechins
1 Cat’s Claw
1 Cannabidiol
1 Zinc
1 irinotecan
1 Polyphenols
1 Cyclopamine
1 Dichloroacetophenone(2,2-)
1 Dandelion Root
1 Echinacea
1 Ginkgo biloba-EGb 761
1 Electrical Pulses
1 Eurycomanone
1 Sesame seeds and Oil
1 Mung Bean Sprouts
1 MCToil
1 Gamma-aminobutyric acid
1 Ginkgo biloba
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Geldanamycin
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Arsenic trioxide
1 Graviola
1 Germacranolide sesquiterpene lactone
1 Hibiscus sabdariffa
1 Hyperthermia
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Indole-3-carbinol
1 Isobavachalcone
1 iodine
1 Anthocyanins
1 Licorice
1 Methylene blue
1 Metformin
1 Magnesium
1 Bicarbonate(Sodium)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 Cisplatin
1 Psoralidin
1 Parthenolide
1 enzalutamide
1 Rauwolfia serpentina/Indian Snakeroot
1 salinomycin
1 Date Fruit Extract
1 cetuximab
1 Tomatine
1 Vitamin B3,Niacin
1 Vitamin D3
1 Vitamin E
1 Vitamin K2
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:792  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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