| 3897- | MCT, | The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells |
| - | in-vitro, | AD, | NA |
| 3896- | MCT, | Improvement of Main Cognitive Functions in Patients with Alzheimer's Disease after Treatment with Coconut Oil Enriched Mediterranean Diet: A Pilot Study |
| - | Trial, | AD, | NA |
| 3895- | MCT, | How does coconut oil affect cognitive performance in alzheimer patients? |
| - | Human, | AD, | NA |
| 2500- | meben, | Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme |
| - | in-vitro, | GBM, | U87MG | - | in-vivo, | GBM, | NA |
| 1899- | MeJa, | Methyl jasmonate induces production of reactive oxygen species and alterations in mitochondrial dynamics that precede photosynthetic dysfunction and subsequent cell death |
| - | in-vitro, | NA, | NA |
| 1898- | MeJa, | Methyl jasmonate and its potential in cancer therapy |
| - | Review, | Var, | NA |
| 1775- | MEL, | Chemo, | Rad, | A Systematic Review of the Chemo/Radioprotective Effects of Melatonin against Ototoxic Adverse Effects Induced by Chemotherapy and Radiotherapy |
| - | Review, | Var, | NA |
| 1776- | MEL, | Therapeutic strategies of melatonin in cancer patients: a systematic review and meta-analysis |
| - | Review, | NA, | NA |
| 1783- | MEL, | The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials |
| - | Review, | Var, | NA |
| 1786- | MEL, | What is known about melatonin, chemotherapy and altered gene expression in breast cancer (Review) |
| - | Review, | NA, | NA |
| 1785- | MEL, | Antitumoral melatonin-loaded nanostructured lipid carriers |
| - | in-vitro, | Var, | NA |
| 1784- | MEL, | Melatonin as adjuvant cancer care with and without chemotherapy: a systematic review and meta-analysis of randomized trials |
| - | Review, | NA, | NA |
| 1782- | MEL, | Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities |
| - | Review, | Var, | NA |
| 1781- | MEL, | Melatonin in patients with cancer receiving chemotherapy: a randomized, double-blind, placebo-controlled trial |
| - | Trial, | Lung, | NA |
| 1780- | MEL, | Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing |
| - | Review, | Var, | NA |
| 1779- | MEL, | Therapeutic Potential of Melatonin Counteracting Chemotherapy-Induced Toxicity in Breast Cancer Patients: A Systematic Review |
| - | Review, | BC, | NA |
| 1778- | MEL, | Melatonin: a well-documented antioxidant with conditional pro-oxidant actions |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 1777- | MEL, | Melatonin as an antioxidant: under promises but over delivers |
| - | Review, | NA, | NA |
| 7495- | MEL, | Melatonin: a promising neuroprotective agent for cerebral ischemia-reperfusion injury |
| - | Review, | Stroke, | NA |
| 7494- | MEL, | Sul, | Medical and surgical treatments for tinnitus: the efficacy of combined treatment with sulodexide and melatonin |
| - | Trial, | Nor, | NA |
| 7493- | MEL, | Effect of melatonin supplementation on tinnitus: systematic literature review and meta-analysis Melatonin and Tinnitus |
| - | Review, | Nor, | NA |
| 6419- | MEL, | The potential influence of melatonin on mitochondrial quality control: a review |
| - | Review, | Nor, | NA |
| 6418- | MEL, | RES, | Melatonin improves mitochondrial function by preventing mitochondrial fission in cadmium-induced rat proximal tubular cell injury via SIRT1-PGC-1α pathway activation |
| - | in-vivo, | AD, | NA |
| 995- | MEL, | Melatonin Treatment Triggers Metabolic and Intracellular pH Imbalance in Glioblastoma |
| - | vitro+vivo, | GBM, | NA |
| 971- | MEL, | Melatonin down-regulates HIF-1 alpha expression through inhibition of protein translation in prostate cancer cells |
| - | in-vitro, | Pca, | DU145 | - | in-vitro, | Pca, | PC3 | - | in-vitro, | Pca, | LNCaP |
| 1063- | MEL, | HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | PC9 |
| 1042- | MEL, | Melatonin Downregulates PD-L1 Expression and Modulates Tumor Immunity in KRAS-Mutant Non-Small Cell Lung Cancer |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H460 | - | in-vitro, | Lung, | LLC1 |
| 4705- | MEL, | Melatonin: beyond circadian regulation - exploring its diverse physiological roles and therapeutic potential |
| - | Review, | Nor, | NA |
| 6541- | MeSal, | Toxicology Answer: Oil of Wintergreen |
| - | Review, | Nor, | NA |
| 6540- | MeSal, | Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK |
| - | in-vitro, | CRC, | HCT116 |
| 6539- | MeSal, | Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation |
| - | in-vitro, | Nor, | NA |
| 6538- | MeSal, | ASA, | Salicylate induces AMPK and inhibits c-MYC to activate a NRF2/ARE/miR-34a/b/c cascade resulting in suppression of colorectal cancer metastasis |
| - | in-vitro, | CRC, | NA |
| 6537- | MeSal, | The ancient drug salicylate directly activates AMP-activated protein kinase |
| - | Review, | Nor, | NA |
| 6536- | MeSal, | Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cells |
| - | in-vitro, | PC, | PANC1 | - | in-vitro, | PC, | Bxpc-3 |
| 6535- | MeSal, | Phytochemistry and Biological Profile of Gaultheria procumbens L. and Wintergreen Essential Oil: From Traditional Application to Molecular Mechanisms and Therapeutic Targets |
| 6534- | MeSal, | Volatile Constituent Analysis of Wintergreen Essential Oil and Comparison with Synthetic Methyl Salicylate for Authentication |
| - | Study, | Nor, | NA |
| 1204- | MET, | Metformin induces ferroptosis through the Nrf2/HO-1 signaling in lung cancer |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H1299 |
| 1066- | MET, | Metformin increases PDH and suppresses HIF-1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma |
| - | in-vitro, | SCC, | NA |
| 1043- | MET, | immuno, | Metformin reduces PD-L1 on tumor cells and enhances the anti-tumor immune response generated by vaccine immunotherapy |
| - | in-vitro, | NA, | NA |
| 994- | MET, | Tumor metabolism destruction via metformin-based glycolysis inhibition and glucose oxidase-mediated glucose deprivation for enhanced cancer therapy |
| - | in-vitro, | Var, | NA |
| 970- | MET, | Metformin suppresses HIF-1α expression in cancer-associated fibroblasts to prevent tumor-stromal cross talk in breast cancer |
| 5803- | MET, | carbop, | Metformin, at Concentrations Corresponding to the Treatment of Diabetes, Potentiates the Cytotoxic Effects of Carboplatin in Cultures of Ovarian Cancer Cells |
| - | in-vitro, | Ovarian, | A2780S | - | in-vitro, | Ovarian, | SKOV3 |
| 5804- | MET, | NIV, | Durable Response to Nivolumab Combined With Metformin in Advanced Pancreatic Cancer: A Case Report With Seven Years of Follow-Up. |
| - | Case Report, | PC, | NA |
| 5785- | MET, | Metformin improves healthspan and lifespan in mice |
| - | in-vivo, | Nor, | NA |
| 5796- | MET, | Tumor, whole blood, plasma, and tissue concentrations of metformin in lung cancer patients |
| - | Human, | Lung, | NA |
| 5795- | MET, | Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | Diabetic, | NA |
| 5800- | MET, | Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect |
| - | Review, | Var, | NA |
| 2456- | MET, | Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | NA, | NA |
| 2457- | MET, | Metformin Impairs Glucose Consumption and Survival in Calu-1 Cells by Direct Inhibition of Hexokinase-II |
| - | in-vitro, | Lung, | Calu-1 |
| 2493- | MET, | Metformin Inhibits Gluconeogenesis by a Redox-Dependent Mechanism In Vivo |
| - | in-vivo, | Nor, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid