Dose Cancer Research Results

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Drug dosage vs efficacy, and actual dosage number of research papers.


Scientific Papers found: Click to Expand⟱
7337- Gra,    Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer
- in-vitro, Pca, NA
other↝, eff↝, BioAv↝, TumCD↓, TumCG↓, Dose↝, other↝,
7328- GSE,    Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
- Trial, Nor, NA
*Dose↝, *BP↓, *other↝, *eff↑,
7324- GSE,    A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention
- Trial, Lung, NA
BioAv↑, toxicity↝, Ki-67↓, miR-106b↓, chemoPv↑, Dose↝, miR-19b↓, PTEN↑, IGF-2R↑, p‑Akt↓, PGE2↓, PGI2↓, COX2/PTGS2↓, Apoptosis↑, TumCP↓, Inflam↓, cardioP↑,
7323- GSE,    Grape seed procyanidin extract against lung cancer: the role of microrna-106b, bioavailability, and bioactivity
- vitro+vivo, Lung, NA
miR-106b↓, P21↑, TumCG↓, Dose↝,
7322- GSE,    MicroRNA-19a/b mediates grape seed procyanidin extract-induced anti-neoplastic effects against lung cancer
- vitro+vivo, Lung, A549 - in-vitro, Lung, H520 - in-vitro, Lung, H1299 - in-vitro, Nor, BEAS-2B
miR-19b↓, IGF-2R↑, PTEN↑, p‑Akt↓, Dose↝,
7329- GSE,    Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
- Trial, Nor, NA
*Dose↝, *BP↓,
6561- GSL,    Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic-Metabolizing Enzymes
- in-vivo, Nor, NA
*Inflam↓, *antiOx↑, *neuroP↑, *AntiCan↑, *BioAv↝, *Dose↝, *toxicity↓, *Catalase↑, *NADPH↑, *GSR↑, *ALAT∅, *AST∅,
7134- GSL,    Phase I study of oral spirogermanium
- Trial, NA, NA
*Dose↝, toxicity↝, Bil∅, toxicity↝, Dose↓,
7485- H2,    Molecular hydrogen inhibits neuroinflammation and ameliorates depressive-like behaviors and short-term cognitive impairment in senescence-accelerated mouse prone 8 mice
- in-vivo, Nor, NA
*Dose↑, *cognitive↑, *memory↑,
7481- H2,  Rad,    Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy
- Trial, Var, NA
Dose↝, CRP↓, NLR↓, IL6↓, AntiTum∅, *toxicity↓, Inflam↓, radioP↑, *IBI↑, *ROS↓,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, eff↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑,
7484- H2,    Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer's Disease Models
- in-vivo, AD, NA
*Dose↝, *cognitive↑, *ROS↓, *Inflam↓, *neuroP↑, *memory↑, *Catalase↑, *TNF-α↓, *Aβ↓, *GABA↓, *H2O2↓, *GFAP↓, *antiOx↑, *NRF2↑,
7487- H2,    A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives
- Review, Nor, NA
*Inflam↓, *antiOx↓, *Stress↓, *Dose↝, *cardioP↑, *GastroP↑, *BBB↑, *eff↑, *toxicity↓, *Dose↝, *hepatoP↑, *ROS↓, *SOD↑, *TBARS↓, *HDL↑, *LDL↓, *Obesity↓, *GSH↑, *TNF-α↓, *GutMicro↑, *DNAdam↓, *γH2AX↓, *p‑p38↓, *NF-kB↓,
7486- H2,    Effects of hydrogen-rich water on blood uric acid in patients with hyperuricemia: A randomized placebo-controlled trial
- Trial, Nor, NA
*eff↑, *uricA↓, *toxicity↓, *antiOx↑, *Inflam↓, *Dose↝, *Dose↝, *Dose↝, *toxicity↓, *Dose↓, *ROS↓,
7489- H2,    Molecular Hydrogen in the Treatment of Respiratory Diseases
- Review, Asthma, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose↓, *Dose↝, *eff↑, *ROS↓, *RNS↓, *NRF2↑, *HO-1↑, *Fenton↓, *NLRP3↓, *NADPH↓, *NOX4↓, *NOX↓, *MPO↓, *NF-kB↓, *TNF-α↓, *IL6↓, *IL1β↓, *HMGB1↓, *IL4↑, *IL10↑, *M2 MC↑, *Treg lymp↝, *Bcl-2↑, *Bcl-xL↑, *PI3K↑, *Akt↑, *JAK2↑, *STAT3↑, *Dose↑, *CD4+↑, *CD25+↑, *FOXP3↑, *MDA↓, *SOD↑, *Catalase↑, *Casp3↓, *Casp9↓, *TBARS↓, *SpO2↑, *VitE↓, *OS↑, *Weight↑, *DNAdam↓, *PGE2↓, *MCP1/CCL2↓, *lipid-P↓, *TumCP↓, *tumCV↓, *TumCMig↓, *TumCI↓, TumW↓, TumVol↓, selectivity↑, QoL↑, ChemoSen↑, chemoP↑, radioP↑, ROS↑, NLRP3↑, Casp3↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓,
7491- H2,    Transdermal hydrogen therapy for psoriasis using cavity-embedded double-conical microneedles
- in-vivo, PSA, NA
*Dose↝, *ROS↓,
7925- H2,    Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
- in-vivo, Asthma, NA
*Dose?, *IL4↓, *IL13↓, *TNF-α↓, *CXCL15↓, *SOD↑, *MDA↓, *MPO↓, *ROS↓, *antiOx↑, *Inflam↓, *Apoptosis↓, *toxicity↓, *Stroke↓, *Airway↓, *Neut↓, *Eos↓, *BALF-Lym↓, *BALF-Infl↓, *AirwayM↓,
7932- H2,    Hydrogen Gas Inhalation Alleviates Airway Inflammation and Oxidative Stress on Ovalbumin-Induced Asthmatic BALB/c Mouse Model
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *ROS↓, *TAC↑, *IgE↓, *Dose↝, *NLR↓, *IL4↓, *IL5↓, *IL13↓, *GM-CSF↓, *NO↓, *GPx↑, *Eos↓,
7926- H2,    Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model
- in-vivo, Asthma, NA
*Dose↝, *Airway↓, *BALF-Infl↓, *Th2↓, *IL4↓, *IgE↓, *MDA↓, *SOD↑, *NF-kB↓, *NRF2↑,
7930- H2,    Hydrogen-rich water alleviates asthma airway inflammation by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation
- in-vivo, Asthma, NA
*GutMicro↑, *Inflam↓, *Dose↝, *AirwayM↓,
7931- H2,    Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells
- in-vitro, Asthma, NA
*p‑FcεRI↓, *NADPH↓, *H2O2↓, *Dose↝,
4307- H2,    Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models
- in-vivo, AD, NA
*cognitive↑, *Inflam↓, *ROS↓, *neuroP↑, *memory↑, *BBB↑, *BDNF↑, *TNF-α↓, *Catalase↑, *IL6↓, *Aβ↓, *GABA↓, *Dose↝,
4308- H2,    A biomimetic upconversion nanoreactors for near-infrared driven H2 release to inhibit tauopathy in Alzheimer's disease therapy
- in-vivo, AD, NA
*BioAv↝, *ROS↓, *p‑tau↓, *Dose↝, *cognitive↑,
2511- H2,    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation
- in-vivo, GBM, U87MG
TumCG↓, OS↑, CD133↓, Ki-67↓, angioG↓, Diff↑, TumCMig↓, TumCI↓, Dose↝, BBB↑, mt-ROS↑,
2524- H2,    Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy
- Trial, NA, NA
hepatoP↑, ALAT↓, AST↓, Dose↝, Dose↝,
2513- H2,    Hydrogen therapy: from mechanism to cerebral diseases
- Review, Stroke, NA
*BBB?, *antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Dose↝,
2512- H2,    Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch
- in-vivo, Asthma, NA
selectivity↑, lactateProd↓, ATP↑, HK2↓, PFK↓, Hif1a↓, PGC-1α↑, Glycolysis↓, OXPHOS↑, Dose↝,
2509- H2,    Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway
- in-vitro, Endo, AN3CA - in-vivo, Endo, NA
selectivity↑, mt-ROS↑, ROS↑, TumW↓, GSDMD↑, Pyro↑, Dose↝, eff↓, TumVol↓,
2506- H2,    Molecular hydrogen suppresses activated Wnt/β-catenin signaling
- in-vivo, Arthritis, NA
*Wnt↓, *β-catenin/ZEB1↓, *Dose↝,
2505- H2,    Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis
- Trial, CRC, NA
PGC-1α↑, Dose↝, CD8+↑, OS↑,
2504- H2,    Hydrogen gas activates coenzyme Q10 to restore exhausted CD8+ T cells, especially PD-1+Tim3+terminal CD8+ T cells, leading to better nivolumab outcomes in patients with lung cancer
- Trial, Lung, NA
CD8+↑, OS↑, eff↝, CoQ10↑, PDT+↓, PGC-1α↑, Dose↝, *toxicity∅,
2503- H2,    Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report
- Case Report, Lung, NA
TumVol↓, OS↑, Dose↝, Dose↝, CEA↓, CA125↓, CYFRA21-1↓, SIRT1↓, COX2/PTGS2↓, IL1β↓, IL6↓, TNF-α↓, HMGB1↓, NF-kB↓, EP2↓,
2527- H2,    The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats
- in-vivo, Wounds, NA
*Dose↝, *SOD↑, *EGF↑, *antiOx↑, *Inflam↓, *Dose↝,
2530- H2,    Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases
- Case Report, PSA, NA
eff↑, Dose↝, eff↑, IL6↓, eff↑,
3152- H2,  VitC,  Rad,    Hydrogen and Vitamin C Combination Therapy: A Novel Method of Radioprotection
- in-vitro, Nor, HUVECs - in-vivo, NA, NA
AntiTum↑, OS↑, QoL↑, TumVol↓, radioP↑, Dose↑, Dose↝, eff↑,
7496- H2S,    Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation
- in-vivo, AD, NA
*neuroP↑, *cognitive↑, *p‑tau↓, *Dose↝,
7523- HCA,    Inhibition of ATP Citrate Lyase by Hydroxycitrate-Loaded Exosomes Suppresses the Survival of Lung Adenocarcinoma Cells
- in-vitro, Lung, NA
ACLY↓, BioAv↓, Dose↝, TumCP↓, FASN↓, IDH1↓, Apoptosis↑, ROS↑, Half-Life↝,
1631- HCA,    An overview of the safety and efficacy of a novel, natural(-)-hydroxycitric acid extract (HCA-SX) for weight management
- Review, Obesity, NA
*ACLY↓, *toxicity∅, *Dose∅,
1645- HCAs,    Chapter 8 - Hydroxycinnamic Acids: Natural Sources, Biosynthesis, Possible Biological Activities, and Roles in Islamic Medicine
- Review, Nor, NA
Dose∅, ROS⇅, Dose∅,
1641- HCAs,    Lung cancer induced by Benzo(A)Pyrene: ChemoProtective effect of sinapic acid in swiss albino mice
- in-vitro, Lung, A549 - in-vivo, Lung, NA
AntiCan↑, Igs↓, lipid-P↓, ROS↑, Casp3↑, Casp9↑, ChemoSideEff↓, Dose∅,
1643- HCAs,    Mechanisms involved in the anticancer effects of sinapic acid
- Review, Var, NA
*BioAv↓, *toxicity↓, Dose∅, ROS⇅, ROS↑, Igs↑, TumCCA↑, TumAuto↑, eff↑, angioG↓, TumCI↓, TumMeta↓, EMT↓, Vim↓, MMP9↓, MMP2↓, Snail↓, E-cadherin↑, p‑Akt↓, GSK‐3β↓, TumCP↓, ChemoSen↑,
1644- HCAs,  PBG,    Artepillin C (3,5-diprenyl-4-hydroxycinnamic acid) sensitizes LNCaP prostate cancer cells to TRAIL-induced apoptosis
- in-vitro, Pca, LNCaP
NF-kB↓, TRAILR↑, Casp8↑, Casp3↑, MMP↓, Dose?,
7509- HCAs,    Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review
- Review, Nor, NA
*BioAv↓, *Dose↝, *BioAv↝, *BioAv↝, *BioAv↑,
7506- HCAs,    A Systematic Review and Comprehensive Evaluation of Human Intervention Studies to Unravel the Bioavailability of Hydroxycinnamic Acids
- Review, Nor, NA
*other↝, *BioAv↝, *Half-Life↝, *other↝, *Dose↝, *BioAv↝,
7508- HCAs,    Natural Sources, Pharmacokinetics, Biological Activities and Health Benefits of Hydroxycinnamic Acids and Their Metabolites
- Review, Nor, NA
*Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *BioAv↓, *antiOx↑, *ROS↓, *Inflam↓, *neuroP↑, *cardioP↑, *hepatoP↑,
7370- HibSad,    Hibiscus sabdariffa leaf induces apoptosis of human prostate cancer cells in vitro and in vivo
- vitro+vivo, Pca, LNCaP - in-vitro, Pca, PC3 - in-vitro, Pca, DU145
eff↑, Dose↝, Bcl-2↓, Mcl-1↓, BAX↑, Cyt‑c↑, FasL↑, eff↑, TumW↓, TumVol↓, other↝,
7369- HibSad,    Components in aqueous Hibiscus rosa-sinensis flower extract inhibit in vitro melanoma cell growth
- in-vitro, Melanoma, B16-BL6 - in-vitro, Nor, LA25
TumCG↓, selectivity↑, Dose↝, eff↑,
7362- HibSad,    The effect of a water extract and anthocyanins of hibiscus sabdariffa L on paracetamol-induced hepatoxicity in rats
- in-vivo, Nor, NA
*Dose↝, *hepatoP↑,
7357- HibSad,    Hibiscus Anthocyanins Extracts Induce Apoptosis by Activating AMP-Activated Protein Kinase in Human Colorectal Cancer Cells
- in-vitro, CRC, LoVo
Apoptosis↑, AMPK↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑Casp3↑, Dose↝, mtDam↑, MMP↓, Akt↓,
7354- HibSad,    Hibiscus sabdariffa Leaf Extract Inhibits Human Prostate Cancer Cell Invasion via Down-Regulation of Akt/NF-kB/MMP-9 Pathway
- vitro+vivo, Pca, LNCaP
MMP9↓, NF-kB↓, Akt↓, TumVol↓, PI3K↓, *antiOx↑, Dose↝,

Showing Research Papers: 551 to 600 of 1061
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1061

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

CD47↓, 1,   IGF-2R↑, 2,   miR-106b↓, 2,   miR-124-3p↓, 1,   NLR↓, 1,   PFS↑, 1,   PGI2↓, 1,  

Redox & Oxidative Stress(tgid=1)

Bil∅, 1,   CoQ10↑, 1,   lipid-P↓, 1,   OXPHOS↑, 1,   ROS↑, 5,   ROS⇅, 2,   mt-ROS↑, 2,  

Mitochondria & Bioenergetics(tgid=3)

ATP↑, 1,   MMP↓, 2,   mtDam↑, 1,   PGC-1α↑, 4,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

ACLY↓, 1,   ALAT↓, 1,   AMPK↑, 1,   FASN↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   IDH1↓, 1,   lactateProd↓, 1,   PFK↓, 1,   SCD1↓, 1,   SIRT1↓, 1,  

Cell Death(tgid=5)

Akt↓, 4,   p‑Akt↓, 3,   Apoptosis↑, 4,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 3,   cl‑Casp3↑, 1,   Casp8↑, 2,   Casp9↑, 1,   Cyt‑c↑, 2,   Fas↑, 1,   FasL↑, 1,   GSDMD↑, 1,   IAP2/BIRC3↓, 1,   Mcl-1↓, 1,   Pyro↑, 1,   TRAILR↑, 1,   TumCD↓, 1,  

Transcription & Epigenetics(tgid=7)

EZH2↓, 1,   other↝, 3,  

Autophagy & Lysosomes(tgid=9)

TumAuto↑, 1,  

Cell Cycle & Senescence(tgid=11)

CDK4↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

CD133↓, 1,   Diff↑, 1,   EMT↓, 1,   EP2↓, 1,   GSK‐3β↓, 1,   PI3K↓, 2,   PTEN↑, 2,   TumCG↓, 4,   Wnt↓, 1,  

Migration(tgid=13)

CEA↓, 1,   E-cadherin↑, 1,   Ki-67↓, 2,   MALAT1↓, 1,   miR-19b↓, 2,   MMP2↓, 1,   MMP9↓, 2,   Snail↓, 1,   TumCI↓, 3,   TumCMig↓, 2,   TumCP↓, 4,   TumMeta↓, 1,   Vim↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 2,   Hif1a↓, 2,   VEGF↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2/PTGS2↓, 2,   CRP↓, 1,   HMGB1↓, 1,   Igs↓, 1,   Igs↑, 1,   IL1β↓, 1,   IL6↓, 3,   Inflam↓, 2,   NF-kB↓, 3,   NK cell↑, 1,   PDT+↓, 1,   PGE2↓, 1,   TNF-α↓, 1,  

Protein Aggregation(tgid=19)

NLRP3↑, 1,  

Hormonal & Nuclear Receptors(tgid=20)

CDK6↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,   BioAv↑, 1,   BioAv↝, 1,   ChemoSen↑, 3,   Dose?, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 23,   Dose∅, 4,   eff↓, 1,   eff↑, 10,   eff↝, 2,   Half-Life↝, 1,   selectivity↑, 5,  

Clinical Biomarkers(tgid=22)

ALAT↓, 1,   AST↓, 1,   Bil∅, 1,   CA125↓, 1,   CEA↓, 1,   CRP↓, 1,   CYFRA21-1↓, 1,   EZH2↓, 1,   IL6↓, 3,   Ki-67↓, 2,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   AntiTum↑, 1,   AntiTum∅, 1,   cardioP↑, 1,   chemoP↑, 2,   chemoPv↑, 1,   ChemoSideEff↓, 1,   hepatoP↑, 1,   NP/CIPN↓, 1,   OS↑, 5,   QoL↑, 3,   radioP↑, 4,   toxicity↝, 3,   TumVol↓, 7,   TumW↓, 3,  

Infection & Microbiome(tgid=24)

CD8+↑, 4,  
Total Targets: 136

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

Airway↓, 2,   AirwayM↓, 2,   BALF-Infl↓, 2,   BALF-Lym↓, 1,   compII↑, 1,   CXCL15↓, 1,   Eos↓, 2,   p‑FcεRI↓, 1,   GFAP↓, 1,   IgE↓, 2,   IL13↓, 2,   NLR↓, 1,   SpO2↑, 1,   Stress↓, 1,   Stroke↓, 2,  

Redox & Oxidative Stress(tgid=1)

antiOx↓, 1,   antiOx↑, 11,   Catalase↑, 5,   Fenton↓, 1,   GPx↑, 2,   GSH↑, 1,   GSR↑, 1,   H2O2↓, 2,   HDL↑, 1,   HO-1↑, 2,   lipid-P↓, 1,   MDA↓, 4,   MPO↓, 3,   NOX4↓, 1,   NRF2↑, 4,   RNS↓, 1,   ROS↓, 12,   SOD↑, 6,   TAC↑, 1,   TBARS↓, 2,   uricA↓, 1,   VitE↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

ATP↑, 1,   compIII↑, 1,   EGF↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

ACLY↓, 1,   ALAT↓, 1,   ALAT∅, 1,   LDL↓, 2,   NADPH↓, 2,   NADPH↑, 1,  

Cell Death(tgid=5)

Akt↑, 2,   Apoptosis↓, 3,   Bcl-2↑, 1,   Bcl-xL↑, 1,   Casp12↓, 1,   Casp3↓, 1,   Casp9↓, 1,   GranB/GZMB↓, 1,   p‑JNK↓, 1,   p38↓, 1,   p‑p38↓, 1,  

Transcription & Epigenetics(tgid=7)

other↑, 1,   other↝, 3,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8)

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9)

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 2,   γH2AX↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

mTOR↓, 1,   PI3K↑, 2,   STAT3↑, 1,   Wnt↓, 1,  

Migration(tgid=13)

APP↓, 1,   TGF-β↑, 1,   Treg lymp↝, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

ATF4↓, 1,   NO↓, 1,  

Barriers & Transport(tgid=15)

BBB?, 1,   BBB↑, 2,   GastroP↑, 1,   IBI↑, 2,  

Immune & Inflammatory Signaling(tgid=16)

CD25+↑, 1,   CD4+↑, 2,   FOXP3↑, 1,   GM-CSF↓, 1,   HMGB1↓, 1,   IFN-γ↓, 1,   IL10↑, 2,   IL1β↓, 2,   IL4↓, 4,   IL4↑, 1,   IL5↓, 1,   IL6↓, 3,   Imm↑, 1,   Inflam↓, 13,   JAK2↑, 1,   LPS↓, 1,   M2 MC↑, 1,   MCP1/CCL2↓, 1,   Neut↓, 1,   NF-kB↓, 4,   PGE2↓, 1,   Th2↓, 1,   TNF-α↓, 6,  

Cellular Microenvironment(tgid=17)

NOX↓, 1,  

Synaptic & Neurotransmission(tgid=18)

BDNF↑, 1,   GABA↓, 2,   p‑tau↓, 2,  

Protein Aggregation(tgid=19)

Aβ↓, 3,   BACE/β-secretase↓, 1,   NLRP3↓, 2,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 3,   BioAv↑, 1,   BioAv↝, 7,   Dose?, 1,   Dose↓, 2,   Dose↑, 2,   Dose↝, 35,   Dose∅, 1,   eff↑, 5,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22)

ALAT↓, 1,   ALAT∅, 1,   AST↓, 1,   AST∅, 1,   BP↓, 2,   creat↓, 1,   GutMicro↑, 3,   IL6↓, 3,   Urea↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   antiPs↑, 1,   cardioP↑, 3,   cognitive↑, 6,   hepatoP↑, 5,   memory↑, 3,   neuroP↑, 7,   Obesity↓, 2,   OS↑, 1,   RenoP↑, 1,   toxicity↓, 7,   toxicity∅, 2,   Weight↑, 1,  

Infection & Microbiome(tgid=24)

Sepsis↓, 1,  
Total Targets: 149

Scientific Paper Hit Count for: Dose, Dosage
39 Magnetic Fields
31 Selenium NanoParticles
27 Hydrogen Gas
24 Radiotherapy/Radiation
22 Curcumin
19 Silver-NanoParticles
19 Resveratrol
19 Chemotherapy
17 Vitamin C (Ascorbic Acid)
16 EGCG (Epigallocatechin Gallate)
16 Selenium
16 Selenite (Sodium)
15 Ginkgo biloba-EGb 761
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Chlorogenic acid
12 Carvacrol
12 Ginger/6-Shogaol/Gingerol
12 Inositol
12 Kaempferol
11 buckwheat sprouts
11 Choline
11 Ellagic acid
11 Sulforaphane (mainly Broccoli)
11 Folic Acid, Vit B9
11 Hyperthermia
10 isoquercitrin
10 Lycopene
10 Hydroxycinnamic-acid
10 Lemongrass Extract/Citral
10 Lactoferrin/Talactoferrin
9 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
9 Baicalein
9 Dichloroacetate
9 Exercise
9 itraconazole
9 Magnetic Field Rotating
8 Rutin
8 Auranofin
8 Melatonin
8 Citric Acid
8 Dandelion Root
8 Ferulic acid
8 Fenbendazole
8 Fisetin
8 Fucoidan
8 Ginkgo biloba
8 Ginkgetin
8 HydroxyTyrosol
8 Silymarin (Milk Thistle) silibinin
7 3-bromopyruvate
7 α-Bisabolol / Chamomile oil
7 Quercetin
7 Mung Bean Sprouts
7 Capsaicin
7 Centella asiatica / Gotu kola → asiaticoside
7 chitosan
7 Echinacea
7 Electrical Pulses
7 Formononetin
7 Gamma-aminobutyric acid
7 Genistein (soy isoflavone)
7 Hibiscus sabdariffa
7 Indole-3-carbinol
7 Thymoquinone
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Metformin
6 Aspirin
6 Astaxanthin
6 Vitexin
6 Caffeic acid
6 immunotherapy
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Eugenol
6 Ivermectin
6 Vitamin D3
6 Honokiol
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 iodine
6 Inulin Prebiotic
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Cynara scolymus/Globe Artichoke/Artichoke Extract
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Paclitaxel/Taxol
5 Boron
5 isoorientin
5 Isovitexin
5 Chocolate
5 Spermidine
5 Oxygen, Hyperbaric
5 diet FMD Fasting Mimicking Diet
5 Vitamin B12
5 Gossypol/AT-101
5 Grapeseed extract
5 Isoliquiritigenin
5 Licorice
5 isoflavones
5 Licochalcone A
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 EMF
5 Rosmarinic acid
5 VitK3,menadione
4 cetuximab
4 Cisplatin
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Celastrol
4 Chrysin
4 Chyawanprash
4 Cichoric acid / Chicoric acid
4 Coenzyme Q10
4 HydroxyCitric Acid
4 Garcinol
4 Diclofenac
4 Docosahexaenoic Acid
4 eicosapentaenoic acid
4 Shilajit/Fulvic Acid
4 Gallic acid
4 capecitabine
4 probiotics
4 Propyl gallate
3 Astragalus
3 Fennel Oil/Foeniculum vulgare
3 Angelica archangelica / Garden Angelica
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Beta-Caryophyllene
3 Bromelain
3 borneol
3 Cat’s Claw
3 chaetocin
3 doxorubicin
3 Calorie Restriction Mimetics
3 Crocetin
3 Dasatinib/Phyrago
3 Disulfiram
3 Eurycomanone
3 Silicic Acid
3 Gambogic Acid
3 Huperzine A/Huperzia serrata
3 Isobavachalcone
3 Lapatinib
3 metronomic chemo
3 Methylsulfonylmethane
3 Oleuropein
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Turmerones
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 1,8-Cineole
2 Photodynamic Therapy
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 DTS(dibenzyl trisulphide) from Anamu
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Bortezomib
2 Lecithin
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 Cynaropicrin
2 diet Plant based
2 diet Short Term Fasting
2 D-limonene
2 Emodin
2 5-fluorouracil
2 Evodiamine
2 Vitamin B6,pyridoxine
2 Flickering Light Stimulation
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Germanium inorganic
2 Geraniol
2 Ginkgolide B
2 Gold NanoParticles
2 Germacranolide sesquiterpene lactone
2 Helleborus niger extracts – Christmas Rose
2 Recombinant Methioninase
2 Juglone
2 Potassium
2 L-ornithine
2 Lactobacillus
2 Luteolin
2 nivolumab
2 Iron
2 Niclosamide (Niclocide)
2 Bifidobacterium
2 Phosphatidylserine
2 Rauwolfia serpentina/Indian Snakeroot
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Annona atemoya Leaf Extract
1 Anethole/trans-Anethole
1 Acer okamotoanum
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 brusatol
1 Bruteridin(bergamot juice)
1 Black Seed Oil/Nigella sativa
1 urea
1 Catechins
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Chlorophyllin
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 CUSP9
1 Cysteamine
1 diet Ketogenic
1 Dipyridamole
1 Docetaxel
1 Zinc
1 Protocatechuic acid
1 Estragole
1 Aluminum
1 ferumoxytol
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Arsenic trioxide
1 Vitamin A, Retinoic Acid
1 Bifidobacterium animalis subsp. lactis GCL2505
1 Glabrescione B
1 carboplatin
1 Graviola
1 hydrogen sulfide
1 High-Ozonide Oil
1 Hormone replacement therapy
1 Hyperoside
1 Extracorporeal Shock Wave Therapy
1 Anthocyanins
1 Gemcitabine (Gemzar)
1 lambertianic acid
1 Lapachol
1 Lasiodin
1 MCToil
1 Sulodexide
1 magnetic nanoparticles
1 Mistletoe/Viscum album Extracts
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 ipilimumab
1 Aidi injection
1 Phenolic Acids
1 Polyphenols
1 alpha Linolenic acid
1 Pterostilbene
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 Sinapic acid
1 salinomycin
1 α-Santalol/Sandalwood oil
1 Sulfasalazine
1 irinotecan
1 Terpinen-4-ol / Tea Tree Oil
1 Taurine
1 Triphala
1 triptolide
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vanillic Acid
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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