| Source: |
| Type: |
| Drug dosage vs efficacy, and actual dosage number of research papers. |
| 7350- | HibSad, | Hibiscus polyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathway |
| - | in-vitro, | GC, | AGS |
| 7349- | HibSad, | Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract |
| - | Trial, | Nor, | NA |
| 7343- | Hne, | Comparative Evaluation of the Potential Antitumor of Helleborus purpurascens in Skin and Breast Cancer |
| - | in-vitro, | Melanoma, | A431 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | Nor, | HaCaT | - | in-vitro, | Nor, | JB6 |
| 7466- | HNK, | PDT, | MET, | Enhanced integrated therapy for breast cancer employing Honokiol-loaded mesoporous polydopamine nanoparticles in conjunction with photothermal effects and low-dose metformin |
| - | in-vitro, | BC, | NA |
| 7465- | HNK, | Aptamer-modified GSH-degradable honokiol polyprodrug nanoparticles for ovarian cancer-specific targeting therapy |
| - | in-vitro, | Ovarian, | NA |
| 7461- | HNK, | Honokiol: a potent chemotherapy candidate for human colorectal carcinoma |
| - | vitro+vivo, | CRC, | RKO |
| 2873- | HNK, | Honokiol Alleviates Oxidative Stress-Induced Neurotoxicity via Activation of Nrf2 |
| - | in-vitro, | Nor, | PC12 |
| 2864- | HNK, | Honokiol: A Review of Its Anticancer Potential and Mechanisms |
| - | Review, | Var, | NA |
| 2079- | HNK, | Honokiol Microemulsion Causes Stage-Dependent Toxicity Via Dual Roles in Oxidation-Reduction and Apoptosis through FoxO Signaling Pathway |
| - | in-vitro, | Nor, | PC12 |
| 7371- | HOO, | Phytochemical characterization of peanut oil and its ozonized form to explore biological activities in vitro |
| 7651- | HPT, | Rad, | Hyperthermia inhibits homologous recombination repair and sensitizes cells to ionizing radiation in a time- and temperature-dependent manner |
| - | in-vitro, | Var, | NA |
| - | in-vivo, | Laryn, | FaDu |
| 7599- | HPT, | Rad, | Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome |
| - | Review, | Var, | NA |
| 7618- | HPT, | ESHO 2-85. Hyperthermia as an adjuvant to radiation therapy in the treatment of advanced neck nodes: A randomized multicenter study by the European Society for Hyperthermic Oncology |
| - | Trial, | Pca, | NA | - | Trial, | BC, | NA |
| 7622- | HPT, | A Review of the Current Clinical Evidence for Loco-Regional Moderate Hyperthermia in the Adjunct Management of Cancers |
| - | Review, | Var, | NA |
| 7577- | HPT, | Rad, | Randomized trial of hyperthermia and radiation for superficial tumors |
| - | Trial, | Var, | NA |
| 7575- | HPT, | Rad, | Chemo, | immuno, | From Localized Mild Hyperthermia to Improved Tumor Oxygenation: Physiological Mechanisms Critically Involved in Oncologic Thermo-Radio-Immunotherapy |
| 7574- | HPT, | Oxy, | Improvement of tumor oxygenation by mild hyperthermia |
| 7572- | HPT, | Rad, | The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination |
| - | in-vitro, | Cerv, | HeLa | - | in-vitro, | Laryn, | FaDu |
| 7477- | HRT, | Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis |
| - | Trial, | Nor, | NA |
| 7524- | HT, | The Pharmaceutical Formulation Plays a Pivotal Role in Hydroxytyrosol Pharmacokinetics |
| - | Trial, | Nor, | NA |
| 7540- | HT, | Discovery of hydroxytyrosol as thioredoxin reductase 1 inhibitor to induce apoptosis and G1/S cell cycle arrest in human colorectal cancer cells via ROS generation |
| - | in-vitro, | CRC, | HCT8 | - | in-vitro, | CRC, | HCT116 |
| 7526- | HT, | Hydroxytyrosol in functional hydroxytyrosol-enriched biscuits is highly bioavailable and decreases oxidised low density lipoprotein levels in humans |
| - | Trial, | Nor, | NA |
| 7529- | HT, | Diet Supplementation with Hydroxytyrosol Ameliorates Brain Pathology and Restores Cognitive Functions in a Mouse Model of Amyloid-β Deposition |
| - | in-vivo, | AD, | NA |
| 7536- | HT, | Effects of Desert Olive Tree Pearls Containing High Hydroxytyrosol Concentrations on the Cognitive Functions of Middle-Aged and Older Adults |
| - | Trial, | AD, | NA |
| 7539- | HT, | Polyphenols Extracts from Oil Production Waste Products (OPWPs) Reduce Cell Viability and Exert Anti-Inflammatory Activity via PPARγ Induction in Colorectal Cancer Cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | LoVo |
| 7541- | HT, | Hydroxytyrosol Supplementation Modifies Plasma Levels of Tissue Inhibitor of Metallopeptidase 1 in Women with Breast Cancer |
| - | Trial, | BC, | NA |
| 7479- | Hup, | A phase II trial of huperzine A in mild to moderate Alzheimer disease |
| - | Trial, | AD, | NA |
| 7480- | Hup, | Pharmacokinetics of huperzine A following oral administration to human volunteers |
| - | Trial, | AD, | NA |
| 3803- | Hup, | Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 7563- | HYP, | Hyperoside alleviates macrophages and microglia-mediated neuroinflammation and oxidative stress through activating PI3K/AKT and Nrf2/HO-1 signaling pathway post spinal cord injury |
| - | vitro+vivo, | Nor, | NA |
| 7602- | I3C, | Dose-ranging study of indole-3-carbinol for breast cancer prevention |
| - | Trial, | BC, | NA |
| 7611- | I3C, | Long-term responses of women to indole-3-carbinol or a high fiber diet |
| - | Trial, | Nor, | NA |
| 7587- | I3C, | Indole-3-Carbinol, a Phytochemical Aryl Hydrocarbon Receptor-Ligand, Induces the mRNA Overexpression of UBE2L3 and Cell Proliferation Arrest |
| - | in-vitro, | Cerv, | HeLa |
| 7595- | I3C, | Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans |
| - | Human, | Nor, | NA |
| 7580- | I3C, | Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmethane |
| - | Trial, | NA, | NA |
| 7581- | I3C, | A phase I study of indole-3-carbinol in women: tolerability and effects |
| - | Trial, | Nor, | NA |
| 7594- | I3C, | Effects of indole-3-carbinol on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers |
| - | Human, | Nor, | NA |
| 7771- | IBC, | Isobavachalcone induces concurrent apoptosis and pyroptosis in anaplastic thyroid cancer cells by modulating the caspase-mediated cleavage of PARP and GSDME |
| - | vitro+vivo, | Thyroid, | CAL-62 |
| 7709- | IBC, | Isobavachalcone ameliorates cognitive deficits, and Aβ and tau pathologies in triple-transgenic mice with Alzheimer's disease |
| - | in-vivo, | AD, | NA |
| 7711- | IBC, | Isobavachalcone, a natural sirtuin 2 inhibitor, exhibits anti-triple-negative breast cancer efficacy in vitro and in vivo |
| - | vitro+vivo, | BC, | NA |
| 7616- | Ins, | A phase I study of myo-inositol for lung cancer chemoprevention |
| - | Trial, | Nor, | NA |
| 7615- | Ins, | A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia |
| 7648- | Ins, | Suppression of lung and liver carcinogenesis in mice by oral administration of myo-inositol |
| - | in-vivo, | Liver, | NA |
| 7637- | Ins, | Investigating the mechanism of inositol against paclitaxel chemoresistance on triple-negative breast cancer by using 7T multiparametric MRI and mitochondrial changes |
| - | vitro+vivo, | BC, | 4T1 |
| 7635- | Ins, | The Role of Inositols in Endocrine and Neuroendocrine Tumors |
| - | Review, | Thyroid, | NA |
| 7636- | Ins, | Myo-Inositol: Pharmacokinetics, Biological Functions, and Therapeutic Potential in Liver Protection: Insights from Preclinical Models |
| 7638- | Ins, | d-Chiro-Inositol in Clinical Practice: A Perspective from the Experts Group on Inositol in Basic and Clinical Research (EGOI) |
| - | Review, | Nor, | NA |
| 7643- | Ins, | IP6, | Efficacy of IP6 + inositol in the treatment of breast cancer patients receiving chemotherapy: prospective, randomized, pilot clinical stud |
| - | Trial, | BC, | NA |
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1114 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid