Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.
Scientific Papers found: Click to Expand⟱
7925- H2,    Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
- in-vivo, Asthma, NA
*Dose?, *IL4↓, *IL13↓, *TNF-α↓, *CXCL15↓, *SOD↑, *MDA↓, *MPO↓, *ROS↓, *antiOx↑, *Inflam↓, *Apoptosis↓, *toxicity↓, *Stroke↓, *Airway↓, *Neut↓, *Eos↓, *BALF-Lym↓, *BALF-Infl↓, *AirwayM↓,
7932- H2,    Hydrogen Gas Inhalation Alleviates Airway Inflammation and Oxidative Stress on Ovalbumin-Induced Asthmatic BALB/c Mouse Model
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *ROS↓, *TAC↑, *IgE↓, *Dose↝, *NLR↓, *IL4↓, *IL5↓, *IL13↓, *GM-CSF↓, *NO↓, *GPx↑, *Eos↓,
7927- H2,    Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients
- Human, Asthma, NA
*IL8↓, *IL4↓, *IL6↓, *Inflam↓, *Sepsis↓, *Stroke↓, *antiOx↑, *toxicity↓,
7928- H2,    Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis
- in-vivo, Asthma, NA
*IL33↓, *NF-kB↓, *IL1RL1/ST2↓, *ILC2↓, *E-cadherin↑, *ZO-1↑, *Inflam↓,
7929- H2,    Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma
- NA, Asthma, NA
*IL4↓, *IL5↓, *IL13↓, *TNF-α↓, *AirwayM↓, *MUC5AC↓, *COL3A1↓, *VEGF↓, *NF-kB↓, *Inflam↓,
7930- H2,    Hydrogen-rich water alleviates asthma airway inflammation by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation
- in-vivo, Asthma, NA
*GutMicro↑, *Inflam↓, *Dose↝, *AirwayM↓,
7933- H2,    Hydrogen inhalation ameliorates lung inflammation in mice with asthma
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *IL4↓, *IL5↓, *IL13↓, *IL10↑, *TGF-β1↑, *IgE↓, *MDA↓, *SOD↑, *Airway↓,
4345- H2,    The Benefit of Hydrogen Gas as an Adjunctive Therapy for Chronic Obstructive Pulmonary Disease
- Human, NA, NA
*Inflam↓, *antiOx↑, *ROS↓, *NLRP3↑, *NF-kB↓, *SOD↑, *Catalase↑, *AntiAg↑,
4236- H2,    Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model
- in-vivo, Stroke, NA
*neuroP↑, *Inflam↓, *antiOx↑, *BDNF↑, *Casp3↓,
4306- H2,    Molecular Hydrogen as an Emerging Candidate for Preventing Alzheimer’s Disease
- Review, AD, NA
*ROS↓, *memory↑, *neuroP↑, *OS↑, *Inflam↓,
4307- H2,    Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models
- in-vivo, AD, NA
*cognitive↑, *Inflam↓, *ROS↓, *neuroP↑, *memory↑, *BBB↑, *BDNF↑, *TNF-α↓, *Catalase↑, *IL6↓, *Aβ↓, *GABA↓, *Dose↝,
2525- H2,    Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis
- in-vivo, NA, NA
OS↓, cardioP↑, *AST↓, ALAT↓, *ROS↓, *MDA↓, *hepatoP↑, *Inflam↓, chemoP↑,
2523- H2,    Prospects of molecular hydrogen in cancer prevention and treatment
- Review, Var, NA
ROS↓, TumCP↓, TumMeta↓, AntiTum↑, GutMicro↑, Inflam↓, OS↑, radioP↑, selectivity↑, SOD↑, IL1β↑, IL8↑, TNF-α↑, neuroP↑,
2521- H2,    Oxyhydrogen Gas: A Promising Therapeutic Approach for Lung, Breast and Colorectal Cancer
- Review, CRC, NA - Review, Lung, NA - Review, BC, NA
Inflam↑, ROS↓, ChemoSen↑, p‑PI3K↓, p‑Akt↓, QoL↑, GutMicro↑, chemoP↑, radioP↑, *NRF2↑, *Catalase↑, *GPx↑, *HO-1↑, *SOD↑, *TNF-α↓, *IL4↓, *IL6↓, ChemoSen↑, Appetite↑, cognitive↑, Pain↓, Sleep↑, other?,
2516- H2,    Hydrogen Gas in Cancer Treatment
- Review, Var, NA
*Half-Life↓, *ROS↓, *selectivity↑, *SOD↑, *HO-1↑, *NRF2↑, *chemoP↑, *radioP↑, ROS↑, *Inflam↓, eff↑, *TNF-α↓, *IL6↓, *cl‑Casp8↑, *Bax:Bcl2↓, *Apoptosis↓, *cardioP↑, *hepatoP↑, *RenoP↑, *chemoP↑, eff↝, chemoP↑, radioP↑, eff↑, TumCG↓, Ki-67↓, VEGF↓, selectivity↑,
2515- H2,    Recent Advances in Studies of Molecular Hydrogen against Sepsis
- Review, Sepsis, NA
*Sepsis↓, *Inflam↓, *antiOx↑, *ROS↓, *NADPH↓,
2514- H2,    Hydrogen: A Novel Option in Human Disease Treatment
- Review, NA, NA
*Inflam↓, *IL1β↓, *IL6↓, *IL8↓, *IL10↓, *TNF-α↓, *ROS↓, *HO-1↓, *NRF2↑, *ER Stress↓, H2O2↑,
2513- H2,    Hydrogen therapy: from mechanism to cerebral diseases
- Review, Stroke, NA
*BBB?, *antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Dose↝,
2508- H2,    Molecular hydrogen is a promising therapeutic agent for pulmonary disease
- Review, Var, NA - Review, Sepsis, NA
*ROS↓, eff↝, *Inflam↓, *NRF2↑, *HO-1↑, *SOD↑, *Catalase↑, *MPO↑, *ASK1↓, *NADPH↓, *Sepsis↓, *HMGB1↓, ROS↑, NLRP3↑, GSDMD↑, chemoP↑, eff↑,
2527- H2,    The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats
- in-vivo, Wounds, NA
*Dose↝, *SOD↑, *EGF↑, *antiOx↑, *Inflam↓, *Dose↝,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
3761- H2,    Therapeutic Inhalation of Hydrogen Gas for Alzheimer's Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study
- Human, AD, NA
*cognitive↑, *BBB↑, *ROS↓, *NRF2↑, *Inflam↓, *NFAT↓, *FAO↓, *4-HNE↓, *PGC-1α↑, *Ferroptosis↓,
3771- H2,    Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
- Review, AD, NA - Review, Stroke, NA
*cognitive↑, AntiCan↑, *Inflam↓, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *GPx↑, *MDA↑, *BBB↑, *OS↑, *Ca+2↓, *APP↓, *p‑tau↓,
3772- H2,    Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *Inflam↓, *ROS↓, *GutMicro↑, *TNF-α↓, *IL6↓, *IL1β↓, *IL10↓, *Catalase↑, *GSH↑,
3773- H2,    Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases
- Review, Park, NA
*neuroP↑, *antiOx↑, *Inflam↓, *ROS↓, *NADPH↓, *NRF2↑, *BBB↑, *IL1β↓, *IL6↓, *TNF-α↓, *NF-kB↓, *NLRP3↓, *Sepsis↓, *p‑mTOR↓, *AMPK↑, *SIRT1↑, *HO-1↑,
3774- H2,    The role of hydrogen in Alzheimer’s disease
- Review, AD, NA
*Inflam↓, *antiOx↑, *NLRP3↓, *memory↑, *Aβ↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *p‑p38↓, *JNK↓, *ROS↓, *cognitive↑, *ER(estro)↑, *BDNF↑,
3775- H2,    Molecular hydrogen therapy for neurological diseases: a review of current evidence
- Review, AD, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑,
3776- H2,    The role of hydrogen in Alzheimer's disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *NLRP3↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *ROS↓, *BDNF↑,
3787- H2,    Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis
- Review, AD, NA
*Inflam↓, *antiOx↑, *ROS↓, *other↝, *NF-kB↓, *IL2↓, *IL6↓, *TNF-α↓, *HO-1↑, Apoptosis↑, TumAuto↑, *Sepsis↓, *NLRP3↓, Pyro↑,
3764- H2,    Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model
- in-vivo, AD, NA
*memory↑, *Aβ↓, *p‑tau↓, *BAX↓, *ROS↓, *NO↓, *Ca+2↓, *MDA↓, *Catalase↓, *GPx↓, *TNF-α↓, *Bcl-2↑, *VEGF↑, *Inflam↓, *cognitive↑,
3765- H2,    Therapeutic Inhalation of Hydrogen Gas for Alzheimer’s Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study
- Study, AD, NA
*antiOx↑, *Inflam↓, *cognitive↑, *BBB↑,
3766- H2,    The role of hydrogen in Alzheimer′s disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *AMPK↑, *SIRT1↑, *FOXO↑, *mtDam↓, *neuroP↑, *ROS↓, *p38↓, *cognitive↑, *BDNF↑, *memory↑, *lipid-P↓, *IL6↓, *TNF-α↓, *JNK↓, *NF-kB↓, *NLRP3↓,
3767- H2,    The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges
- Review, AD, NA
*Inflam↓, *neuroP↑, *toxicity↓, *antiOx↑, *ROS↓, *NLRP3↓, *IL1β↓, *mtDam↓, *ATP↑, *AMPK↑, *FOXO3↑, *SOD1↑, *Catalase↑, *NRF2↑, *NO↓, *MDA↓, *lipid-P↓, *memory↑, *ER(estro)↓, *BDNF↑, *cognitive↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *BP∅, *BBB↑,
3769- H2S,    Research progress of hydrogen sulfide in Alzheimer's disease from laboratory to hospital: a narrative review
- Review, AD, NA
*APP↓, *Apoptosis↓, *Inflam↓, *antiOx↑, *BP↓, *NLRP3↓, *ROS↓, *Aβ↓, *ER Stress↓,
7499- H2S,    Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms
*TNF-α↓, *Bcl-2↑, *BAX↓, *Casp3↓, *Inflam↓, *Apoptosis↓, *memory↑,
1637- HCA,  OLST,    Orlistat and Hydroxycitrate Ameliorate Colon Cancer in Rats: The Impact of Inflammatory Mediators
- in-vivo, Colon, NA
TumVol↓, OS↑, *IL6↓, *NF-kB↓, *eff↑, *Casp3↓, *TNF-α↓, *Catalase↑, *NO↓, *ROS↓, *Inflam↓, *Apoptosis↓,
1625- HCA,    In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase
- Review, Nor, NA
CRM↑, ACLY↓, TumAuto↑, Inflam↓, TumCG↓, toxicity∅, lipoGen↓, *ROS↓, *OCR↓,
1633- HCA,    Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1α Pathway
- in-vivo, NA, NA - in-vitro, Nor, HUVECs
*other↓, *Inflam↓, *MDA↓, *ROS↓, *Iron↓, *SOD↓, *Hif1a↓, *HO-1↓,
1638- HCAs,    Anticancer potential of hydroxycinnamic acids: mechanisms, bioavailability, and therapeutic applications
- Review, Nor, NA
*BioAv↓, Inflam↓, COX2/PTGS2↓, TumCCA↑, ChemoSen↑, RadioS↑, selectivity↑, ROS↑, DNAdam↑, antiOx↑, SOD↑, Catalase↑, GPx↑, GSH↑, NRF2↑, NF-kB↓, Cyc↓, CDK1↑, P21↑, p27/CDKN1B↑, P53↑, VEGF↓, MAPK↓,
6869- HCAs,  FA,  CA,  RosA,    Exploring the potential of cinnamic acid analogues in alzheimer's disease
- Review, AD, NA
*neuroP↑, *antiOx↓, *Inflam↓, *tau↓, *BioAv↓, *BBB↓, *BioAv↑,
7508- HCAs,    Natural Sources, Pharmacokinetics, Biological Activities and Health Benefits of Hydroxycinnamic Acids and Their Metabolites
- Review, Nor, NA
*Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *BioAv↓, *antiOx↑, *ROS↓, *Inflam↓, *neuroP↑, *cardioP↑, *hepatoP↑,
7364- HibSad,    Hibiscus sabdariffa calyx extract induces anti-proliferative and anti-migratory effects in ovarian cancer
- in-vitro, Ovarian, OVCAR-3
*Inflam↓, *AntiBio↑, *antiOx↑, TumCMig↓, AKT1↓, cycD1/CCND1↓,
7359- HibSad,    Novel Insight into the Cellular and Molecular Signalling Pathways on Cancer Preventing Effects of Hibiscus sabdariffa: A Review - PubMed
- Review, Var, NA
AntiCan↑, TumCP↓, Apoptosis↑, TumCCA↑, P53↑, P21↑, p27/CDKN1B↑, BAD↑, BAX↑, Casp3↑, Casp7↑, Casp8↑, Casp9↑, *AntiBio↑, *Inflam↓, *antiOx↑, *BP↓, *AntiDiabetic↑, HDAC1↓, HDAC3↓, tumCV↓, LDL↓, DNAdam↑, MMP↓, *Catalase↑, *SOD↑, *GPx↑, *GSH↑, *antiOx↑, *ROS↓, TumCMig↓, TumCI↓, selectivity↑, RAS↓, Akt↓, NF-kB↓, MMP2↓, PI3K↓, Bcl-2↓, Bcl-xL↓, PCNA↓, cycA1/CCNA1↓, cycD1/CCND1↓, cycE/CCNE↓,
7341- Hne,    Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment
- Review, Var, NA
angioG↓, TumCP↓, *Inflam↓, *Bacteria↓, *glucose↓, *neuroP↓, *hepatoP↓, *Imm↝,
7468- HNK,    Honokiol and Its Emerging Role in Breast Cancer Therapy
- Review, BC, NA
*ROS↓, *Inflam↓, CSCs↓, ChemoSen↑, BioAv↑, ROS↑, MMP↓, mtDam↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, Casp3↑, Casp9↑, Bcl-2↓, Bcl-xL↓, BAX↑, p‑STAT3↓, AMPK↑, miR-34a↑, EMT↓, HH↓, Shh↓, Gli1↓, PTCH1↓, NF-kB↓, TNF-α↓, IL6↓, Glycolysis↓, GlucoseCon↓, BioAv↓, BioAv↓, Half-Life↝,
7461- HNK,    Honokiol: a potent chemotherapy candidate for human colorectal carcinoma
- vitro+vivo, CRC, RKO
Apoptosis↑, Casp↑, Dose↝, OS↑, *Inflam↓, *AntiThr↑, *antiOx↑, *Half-Life↝, TumCG↓,
7455- HNK,    Honokiol in cancer: Roles in enhancing combination therapy efficacy and preventing post-transplant malignancies
- Review, Var, NA
ChemoSen↑, Imm↝, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiCan↑, *Inflam↓, *antiOx↑, eff↑, *TNF-α↓, *IL1?, *IL6?,
2871- HNK,    Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling
- in-vivo, Nor, NA
*TNF-α↓, *IL1β↓, *IL6↓, *VEGF↓, *NRF2↑, *SOD2↑, *HO-1↑, *Inflam↓, *Pain↓, *NO↓, toxicity↓,
2869- HNK,    Nature's neuroprotector: Honokiol and its promise for Alzheimer's and Parkinson's
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *motorD↑, *Aβ↓, *p‑tau↓, *cognitive↑, *memory↑, *ERK↑, *p‑Akt↑, *PPARγ↑, *PGC-1α↑, *MMP↑, *mt-ROS↓, *SIRT3↑, *IL1β↓, *TNF-α↓, *GRP78/BiP↓, *CHOP/DDIT3↓, *NF-kB↓, *GSK‐3β↓, *β-catenin/ZEB1↑, *Ca+2↓, *AChE↓, *SOD↑, *Catalase↑, *GPx↑,
2868- HNK,    Honokiol: A review of its pharmacological potential and therapeutic insights
- Review, Var, NA - Review, Sepsis, NA
*P-gp/ABCB1↓, *ROS↓, *TNF-α↓, *IL10↓, *IL6↓, eIF2α↑, CHOP/DDIT3↑, GRP78/BiP↑, BAX↑, cl‑Casp9↑, p‑PERK↑, ER Stress↑, Apoptosis↑, MMPs↓, cFLIP↓, CXCR4↓, Twist↓, HDAC↓, BMPs↑, p‑STAT3↓, mTOR↓, EGFR↓, NF-kB↓, Shh↓, VEGF↓, tumCV↓, TumCMig↓, TumCI↓, ERK↓, Akt↓, Bcl-2↓, Nestin↓, CD133↓, p‑cMET↑, RAS↑, chemoP↑, *NRF2↑, *NADPH↓, *p‑Rac1↓, *ROS↓, *IKKα↑, *NF-kB↓, *COX2/PTGS2↓, *PGE2↓, *Casp3↓, *hepatoP↑, *antiOx↑, *GSH↑, *Catalase↑, *RenoP↑, *ALP↓, *AST↓, *ALAT↓, *neuroP↑, *cardioP↑, *HO-1↑, *Inflam↓,

Showing Research Papers: 601 to 650 of 1166
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1166

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↑, 1,   GPx↑, 1,   GSH↑, 1,   H2O2↑, 1,   NRF2↑, 1,   ROS↓, 2,   ROS↑, 4,   SOD↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 2,   mtDam↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACLY↓, 1,   AKT1↓, 1,   ALAT↓, 1,   AMPK↑, 1,   CRM↑, 1,   GlucoseCon↓, 1,   Glycolysis↓, 1,   LDL↓, 1,   lipoGen↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 2,   p‑Akt↓, 1,   Apoptosis↑, 4,   BAD↑, 1,   BAX↑, 3,   Bcl-2↓, 3,   Bcl-xL↓, 2,   Casp↑, 1,   Casp3↑, 2,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 2,   cl‑Casp9↑, 1,   cFLIP↓, 1,   GSDMD↑, 1,   MAPK↓, 1,   p27/CDKN1B↑, 2,   Pyro↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other?, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   eIF2α↑, 1,   ER Stress↑, 1,   GRP78/BiP↑, 1,   p‑PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   P53↑, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↑, 1,   CDK4↓, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 1,   cycD1/CCND1↓, 3,   cycE/CCNE↓, 1,   P21↑, 2,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   p‑cMET↑, 1,   CSCs↓, 1,   EMT↓, 1,   ERK↓, 1,   Gli1↓, 1,   HDAC↓, 1,   HDAC1↓, 1,   HDAC3↓, 1,   HH↓, 1,   miR-34a↑, 1,   mTOR↓, 1,   Nestin↓, 1,   PI3K↓, 1,   p‑PI3K↓, 1,   PTCH1↓, 1,   RAS↓, 1,   RAS↑, 1,   Shh↓, 2,   p‑STAT3↓, 2,   TumCG↓, 4,  

Migration(tgid=13) ⓘ

Ki-67↓, 1,   MMP2↓, 1,   MMPs↓, 1,   TumCI↓, 2,   TumCMig↓, 3,   TumCP↓, 3,   TumMeta↓, 1,   Twist↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   EGFR↓, 1,   VEGF↓, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   CXCR4↓, 1,   IL1β↑, 1,   IL6↓, 1,   IL8↑, 1,   Imm↝, 1,   Inflam↓, 3,   Inflam↑, 1,   NF-kB↓, 4,   TNF-α↓, 1,   TNF-α↑, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 1,   ChemoSen↑, 5,   Dose↝, 1,   eff↑, 4,   eff↝, 2,   Half-Life↝, 1,   RadioS↑, 1,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   BMPs↑, 1,   EGFR↓, 1,   GutMicro↑, 2,   IL6↓, 1,   Ki-67↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiTum↑, 1,   Appetite↑, 1,   cardioP↑, 1,   chemoP↑, 5,   cognitive↑, 1,   neuroP↑, 1,   OS↓, 1,   OS↑, 3,   Pain↓, 1,   QoL↑, 1,   radioP↑, 3,   Sleep↑, 1,   toxicity↓, 1,   toxicity∅, 1,   TumVol↓, 1,  
Total Targets: 132

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

Airway↓, 2,   AirwayM↓, 3,   AntiBio↑, 2,   BALF-Infl↓, 1,   BALF-Lym↓, 1,   CXCL15↓, 1,   Eos↓, 2,   IgE↓, 2,   IL13↓, 4,   IL1RL1/ST2↓, 1,   ILC2↓, 1,   MUC5AC↓, 1,   NLR↓, 1,   Stroke↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 1,   antiOx↓, 1,   antiOx↑, 27,   Catalase↓, 1,   Catalase↑, 11,   Ferroptosis↓, 1,   GPx↓, 1,   GPx↑, 5,   GPx1↑, 1,   GSH↑, 3,   HO-1↓, 2,   HO-1↑, 8,   Iron↓, 1,   lipid-P↓, 2,   MDA↓, 7,   MDA↑, 1,   MPO↓, 1,   MPO↑, 1,   NRF2↑, 10,   ROS↓, 30,   mt-ROS↓, 2,   SIRT3↑, 2,   SOD↓, 1,   SOD↑, 10,   SOD1↑, 1,   SOD2↑, 1,   TAC↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   EGF↑, 1,   MMP↑, 1,   mtDam↓, 2,   OCR↓, 1,   PGC-1α↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   AMPK↑, 5,   FAO↓, 1,   glucose↓, 1,   LDL↓, 1,   NADPH↓, 5,   PPARγ↑, 1,   SIRT1↑, 5,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   p‑Akt↑, 1,   Apoptosis↓, 6,   ASK1↓, 1,   BAX↓, 2,   Bax:Bcl2↓, 1,   Bcl-2↑, 2,   Casp3↓, 4,   cl‑Casp8↑, 1,   Ferroptosis↓, 1,   JNK↓, 2,   p38↓, 1,   p‑p38↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   other↓, 2,   other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 2,   GRP78/BiP↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   FOXO↑, 1,   FOXO3↑, 4,   GSK‐3β↓, 1,   mTOR↓, 1,   p‑mTOR↓, 1,   PTEN↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 2,   APP↓, 3,   Ca+2↓, 3,   COL3A1↓, 1,   E-cadherin↑, 1,   NFAT↓, 1,   p‑Rac1↓, 1,   TGF-β1↑, 1,   ZO-1↑, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↓, 1,   NO↓, 6,   VEGF↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↓, 1,   BBB↑, 6,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   GM-CSF↓, 1,   HMGB1↓, 1,   IKKα↑, 1,   IL1?, 1,   IL10↓, 3,   IL10↑, 1,   IL1β↓, 7,   IL2↓, 1,   IL33↓, 1,   IL4↓, 6,   IL5↓, 3,   IL6?, 1,   IL6↓, 13,   IL8↓, 2,   Imm↝, 1,   Inflam↓, 46,   Neut↓, 1,   NF-kB↓, 10,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 18,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↑, 6,   GABA↓, 1,   tau↓, 1,   p‑tau↓, 3,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 7,   BACE/β-secretase↓, 1,   NLRP3↓, 8,   NLRP3↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER(estro)↓, 1,   ER(estro)↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 1,   Dose?, 1,   Dose↝, 13,   eff↑, 1,   Half-Life↓, 1,   Half-Life↝, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 2,   BP↓, 2,   BP∅, 1,   GutMicro↑, 2,   IL6?, 1,   IL6↓, 13,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 1,   cardioP↑, 5,   chemoP↑, 2,   cognitive↑, 12,   hepatoP↓, 1,   hepatoP↑, 5,   memory↑, 9,   motorD↑, 1,   neuroP↓, 1,   neuroP↑, 14,   OS↑, 2,   Pain↓, 1,   radioP↑, 1,   RenoP↑, 2,   toxicity↓, 3,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   Sepsis↓, 6,  
Total Targets: 166

Scientific Paper Hit Count for: Inflam, inflammation
43 Hydrogen Gas
40 Curcumin
33 Thymoquinone
32 Quercetin
31 Magnetic Fields
30 Silymarin (Milk Thistle) silibinin
23 Resveratrol
18 Alpha-Lipoic-Acid
18 Berberine
18 Selenium NanoParticles
18 Fisetin
18 Rosmarinic acid
17 Lycopene
16 Ashwagandha(Withaferin A)
16 Ferulic acid
15 Capsaicin
15 Carvacrol
15 Kaempferol
15 Sulforaphane (mainly Broccoli)
15 Urolithin
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Emodin
14 Eugenol
14 Honokiol
13 Silver-NanoParticles
13 Beta-Caryophyllene
13 Licochalcone A
12 Radiotherapy/Radiation
12 Baicalein
12 Chlorogenic acid
12 Chrysin
11 Cinnamon
11 Isoliquiritigenin
10 Crocetin
10 Chemotherapy
10 Dandelion Root
10 EGCG (Epigallocatechin Gallate)
10 Pterostilbene
9 Selenite (Sodium)
9 Isovitexin
9 Boron
9 Ginger/6-Shogaol/Gingerol
8 Astaxanthin
8 Boswellia (frankincense)
8 α-Bisabolol / Chamomile oil
8 Rutin
8 Diclofenac
8 Fucoidan
8 Piperlongumine
8 Vitamin C (Ascorbic Acid)
8 Shikonin
7 Allicin (mainly Garlic)
7 Betulinic acid
7 Vitamin B3,Niacin
7 Butyrate
7 Centella asiatica / Gotu kola → asiaticoside
7 D-limonene
7 Gallic acid
7 Hyperoside
6 1,8-Cineole
6 Artemisinin
6 Aspirin
6 Caffeic acid
6 Thymol-Thymus vulgaris
6 Hydroxycinnamic-acid
6 Garcinol
6 HydroxyTyrosol
6 isoorientin
6 Vitexin
6 Luteolin
6 Magnolol
6 Piperine
5 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
5 Folic Acid, Vit B9
5 Cisplatin
5 Caffeic Acid Phenethyl Ester (CAPE)
5 Celastrol
5 chitosan
5 Chocolate
5 Coenzyme Q10
5 Ellagic acid
5 Shilajit/Fulvic Acid
5 isoquercitrin
5 Lactoferrin/Talactoferrin
5 Magnetic Field Rotating
5 Ursolic acid
4 Bacopa monnieri
4 Cichoric acid / Chicoric acid
4 Carvone
4 Ginkgo biloba-EGb 761
4 Formononetin
4 Ginkgo biloba
4 Geraniol
4 Ginkgetin
4 Isobavachalcone
4 Mung Bean Sprouts
4 Lemongrass Extract/Citral
4 Moringa oleifera
4 nicotinamide adenine dinucleotide
4 Nimbolide
4 Taurine
4 Vitamin B5,Pantothenic Acid
4 Vitamin D3
4 Vitamin K2
3 Anethole/trans-Anethole
3 Lutein
3 Naringin
3 Baicalin
3 Biochanin A
3 Vitamin B12
3 Bromelain
3 doxorubicin
3 Lecithin
3 Carnosine
3 Chyawanprash
3 Spermidine
3 Cucurbitacin
3 Date Fruit Extract
3 Docosahexaenoic Acid
3 eicosapentaenoic acid
3 diet Fermented Foods
3 Exercise
3 Gamma-aminobutyric acid
3 Genistein (soy isoflavone)
3 HydroxyCitric Acid
3 Inositol
3 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
3 Licorice
3 Methylsulfonylmethane
3 α-Santalol/Sandalwood oil
3 Sulfasalazine
3 Vitamin B1/Thiamine
2 Anthocyanins
2 alpha Linolenic acid
2 Fennel Oil/Foeniculum vulgare
2 Melatonin
2 brusatol
2 borneol
2 buckwheat sprouts
2 Paclitaxel/Taxol
2 Cat’s Claw
2 Celecoxib
2 Chlorophyllin
2 Choline
2 methotrexate
2 Selenium
2 Vitamin E
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Galantamine
2 Huperzine A/Huperzia serrata
2 diet Short Term Fasting
2 Dipyridamole
2 Echinacea
2 Eurycomanone
2 flavonoids
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Ginkgolide B
2 Ginseng
2 Grapeseed extract
2 hydrogen sulfide
2 Orlistat
2 Hibiscus sabdariffa
2 Oleuropein
2 iodine
2 Inulin Prebiotic
2 isoflavones
2 Ivermectin
2 Juglone
2 Potassium
2 probiotics
2 Methyl salicylate / Sweet Birch oil
2 Mushroom Lion’s Mane
2 Oleocanthal
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Phosphatidylserine
2 Salvia officinalis
2 Shankhpushpi
2 Salvia miltiorrhiza
2 Terpinen-4-ol / Tea Tree Oil
2 Aflavin-3,3′-digallate
2 Turmerones
1 2-DeoxyGlucose
1 5-Hydroxytryptophan
1 Annona atemoya Seed Extract
1 Astragalus
1 Acetyl-l-carnitine
1 Morin
1 Aloe anthraquinones
1 beta-glucans
1 xanthohumol
1 Cannabidiol
1 beta-carotene(VitA)
1 Vitamin B6,pyridoxine
1 Bifidobacterium
1 Brucea javanica
1 Bruteridin(bergamot juice)
1 Black Seed Oil/Nigella sativa
1 Carnosic acid
1 Cannabichromene
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chaetocin
1 Prebiotic
1 Carica papaya leaf extract
1 Calorie Restriction Mimetics
1 Copper and Cu NanoParticles
1 Rivastigmine
1 Cynaropicrin
1 Deguelin
1 Dihydrocaffeic Acid
1 Disulfiram
1 immunotherapy
1 Electrical Pulses
1 Evodiamine
1 Ascorbyl Palmitate
1 Flickering Light Stimulation
1 Iron
1 Galloflavin
1 Gambogic Acid
1 Ginkgolic acids
1 Bifidobacterium animalis subsp. lactis GCL2505
1 γ-linolenic acid (Borage Oil)
1 Gossypol/AT-101
1 Graviola
1 Germacranolide sesquiterpene lactone
1 Siegesbeckia glabrescens
1 Helleborus niger extracts – Christmas Rose
1 Hops (Humulus lupulus)
1 Indole-3-carbinol
1 Butein
1 Scopoletin
1 Lactobacillus
1 Linalool
1 Zeaxanthin
1 5-fluorouracil
1 MCToil
1 Metformin
1 Neem
1 Oregano
1 Peppermint
1 Propyl gallate
1 Phenolic Acids
1 Psoralidin
1 Parthenolide
1 EMF
1 Radio Frequency
1 Aromatherapy
1 Gold NanoParticles
1 Sesame seeds and Oil
1 Silicic Acid
1 cetuximab
1 Terminalia bellirica
1 Thyme
1 Vitamin A, Retinoic Acid
1 Vitamin B2,Riboflavin
1 Zinc
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:953  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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