| Source: |
| Type: |
| Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors. |
| 7776- | IBC, | Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation |
| - | vitro+vivo, | PC, | Panc02 |
| 7775- | IBC, | Isobavachalcone Induces Multiple Cell Death in Human Triple-Negative Breast Cancer MDA-MB-231 Cells |
| - | vitro+vivo, | BC, | MDA-MB-231 |
| 7774- | IBC, | Isobavachalcone isolated from Psoralea corylifolia inhibits cell proliferation and induces apoptosis via inhibiting the AKT/GSK-3β/β-catenin pathway in colorectal cancer cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 |
| 7772- | IBC, | Isobavachalcone inhibits acute myeloid leukemia: Potential role for ROS-dependent mitochondrial apoptosis and differentiation |
| - | vitro+vivo, | AML, | NA |
| 33- | InA, | Inoscavin A, a pyrone compound isolated from a Sanghuangporus vaninii extract, inhibits colon cancer cell growth and induces cell apoptosis via the hedgehog signaling pathway |
| - | vitro+vivo, | Colon, | NA |
| 7671- | iod, | Uptake and antiproliferative effect of molecular iodine in the MCF-7 breast cancer cell line |
| - | in-vitro, | BC, | MCF7 |
| 7676- | iod, | Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR) |
| - | in-vivo, | BC, | NA |
| 7677- | iod, | Activation of peroxisome proliferator-activated receptor gamma is crucial for antitumoral effects of 6-iodolactone |
| - | in-vitro, | BC, | MCF7 |
| 7688- | iod, | CEL, | Iodine prevents the increase of testosterone-induced oxidative stress in a model of rat prostatic hyperplasia |
| - | in-vivo, | Pca, | NA |
| 7713- | IP6, | PacT, | Inositol hexaphosphate and paclitaxel: symbiotic treatment of oral cavity squamous cell carcinoma |
| - | in-vitro, | Oral, | Ca9-22 | - | in-vitro, | Oral, | HN5 |
| 7715- | IP6, | Inositol hexaphosphate (IP6) inhibits cellular proliferation in melanoma |
| - | in-vitro, | Melanoma, | HTB68 |
| 7716- | IP6, | Inositol hexaphosphate (IP6): a novel treatment for pancreatic cancer |
| - | in-vitro, | Pca, | MIA PaCa-2 | - | in-vitro, | PC, | PANC1 |
| - | in-vivo, | Pca, | DU145 |
| 7712- | IP6, | Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice |
| - | in-vivo, | Pca, | NA |
| 7719- | IP6, | Effect of inositol hexaphosphate (IP(6)) on human normal and leukaemic haematopoietic cells |
| - | in-vitro, | CML, | NA |
| 7721- | IP6, | Ins, | Effect of phytic acid and inositol on the proliferation and apoptosis of cells derived from colorectal carcinoma |
| - | in-vitro, | CRC, | HT-29 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | SW-620 |
| 7722- | IP6, | Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic |
| - | Review, | Var, | NA |
| 7642- | IP6, | Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway |
| - | in-vitro, | CRC, | NA |
| 7645- | IP6, | Ins, | Anticancer Properties of Inositol Hexaphosphate and Inositol: An Overview |
| 7646- | IP6, | Ins, | Protection against cancer by dietary IP6 and inositol |
| - | Review, | Var, | NA |
| 7690- | IP6, | Ins, | Inositol Hexaphosphate (IP6) and Colon Cancer: From Concepts and First Experiments to Clinical Application |
| - | Review, | Colon, | NA |
| 7691- | IP6, | Inositol Hexaphosphate Suppresses Growth and Induces Apoptosis in Prostate Carcinoma Cells in Culture and Nude Mouse Xenograft: PI3K-Akt Pathway as Potential Target |
| - | vitro+vivo, | Pca, | PC3 | - | in-vitro, | Pca, | C4-2B |
| 7701- | IP6, | Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway |
| - | vitro+vivo, | HCC, | Hep3B | - | NA, | NA, | MHCC-97H |
| 7744- | ISL, | Isoliquiritigenin suppresses fatty acid synthesis and cancer cell migration in anaplastic thyroid carcinoma through AMPK/SREBF1 pathway |
| - | vitro+vivo, | Thyroid, | NA |
| 7763- | ISL, | Harnessing Liquiritigenin: A Flavonoid-Based Approach for the Prevention and Treatment of Cancer |
| 7745- | ISL, | Isoliquiritigenin inhibits colorectal cancer progression by targeting the FGFR4/FASN mediated lipid metabolism pathway |
| - | in-vitro, | CRC, | NA |
| 7748- | ISL, | GEM, | Isoliquiritigenin combined with gemcitabine inhibited lung cancer by suppressing JAK2/STAT3 signaling via lncRNA-p21/miRNA-4534 axis |
| - | NA, | Lung, | NA |
| 7777- | ISL, | Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells |
| - | vitro+vivo, | Gall, | SGC996 |
| 7786- | ISL, | Isoliquiritigenin exhibits anti-proliferative properties in the pituitary independent of estrogen receptor function |
| 7778- | ISL, | Isoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D1, D3, and vasopressin V1A receptors |
| - | Study, | Park, | NA | - | Study, | AD, | NA |
| 7866- | isoO, | Orientin and Cancer Suppression: Molecular Mechanisms and Synergistic Effects |
| - | Review, | Var, | NA |
| 7869- | isoO, | Apoptosis induction and inhibition of invasion and migration in gastric cancer cells by Isoorientin studied using network pharmacology |
| - | in-vitro, | GC, | HGC27 |
| 7853- | isoO, | Natural flavonoid isoorientin and its anticancer mechanisms: a systematic review |
| - | Review, | Var, | NA |
| 7859- | isoO, | Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells |
| - | in-vitro, | PC, | PANC1 |
| 7885- | isoO, | Isoorientin from Gypsophila elegans induces apoptosis in liver cancer cells via mitochondrial-mediated pathway |
| 7882- | isoO, | Isoorientin triggers apoptosis of hepatoblastoma by inducing DNA double-strand breaks and suppressing homologous recombination repair |
| - | in-vitro, | Liver, | NA |
| 7873- | isoO, | Isoorientin attenuates doxorubicin-induced cardiac injury via the activation of MAPK, Akt, and Caspase-dependent signaling pathways |
| - | in-vitro, | Liver, | HepG2 | - | in-vitro, | CRC, | HT-29 | - | in-vitro, | Lung, | A549 |
| 7795- | ISQ, | The Flavonol Isoquercitrin Promotes Mitochondrial-Dependent Apoptosis in SK-Mel-2 Melanoma Cell via the PI3K/AKT/mTOR Pathway |
| - | in-vitro, | Melanoma, | SK-MEL-28 | - | in-vitro, | Nor, | HaCaT |
| 7816- | ISQ, | Isoquercitrin Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Gastric Cancer Cells |
| - | in-vitro, | GC, | AGS | - | in-vitro, | GC, | HGC27 |
| 7812- | ISQ, | Isoquercitrin promotes ferroptosis and oxidative stress in nasopharyngeal carcinoma via the AMPK/NF-κB pathway |
| - | vitro+vivo, | NPC, | CNE1 | - | in-vitro, | NPC, | HNE1 |
| 7847- | ISQ, | Research on the bioactivity of isoquercetin extracted from marestail on bladder cancer EJ cell and the mechanism of its occurrence |
| - | in-vitro, | Bladder, | NA |
| 7796- | ISQ, | Isoquercitrin restrains the proliferation and promotes apoptosis of human osteosarcoma cells by inhibiting the Wnt/β-catenin pathway |
| - | vitro+vivo, | OS, | 143B | - | in-vitro, | OS, | U2OS |
| 7848- | ISQ, | Review of anticancer mechanisms of isoquercitin |
| - | Review, | Var, | NA |
| 8010- | itraC, | Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells |
| - | vitro+vivo, | GC, | MKN45 |
| 7983- | itraC, | Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells |
| - | in-vitro, | Nor, | HUVECs |
| 8009- | itraC, | Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways |
| - | vitro+vivo, | Melanoma, | SK-MEL-28 | - | vitro+vivo, | Melanoma, | A375 |
| 7997- | itraC, | Anti-fungal drug itraconazole exerts anti-cancer effects in oral squamous cell carcinoma via suppressing Hedgehog pathway |
| - | vitro+vivo, | SCC, | NA |
| 7994- | itraC, | From fungus fighter to cancer slayer: itraconazole as a multifaceted candidate for drug-resistant prostate cancer |
| - | Review, | Pca, | NA |
| 7985- | itraC, | Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking |
| - | vitro+vivo, | GBM, | U87MG | - | vitro+vivo, | GBM, | C6 |
| 7986- | itraC, | Open-label, exploratory phase II trial of oral itraconazole for the treatment of basal cell carcinoma |
| - | Trial, | BCC, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:327 State#:% Dir#:%
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