Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
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Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
7898- IVT,    Pharmacokinetics and tissue distribution study of Isovitexin in rats by HPLC-MS/MS
- in-vivo, Nor, NA
*Dose↝, *Half-Life↝, *BioAv↝,
7896- IVT,  VT,    Molecular targets of vitexin and isovitexin in cancer therapy: a critical review
- Review, Var, NA
chemoPv↑, Dose↝, ACE/ACE1↓, Ca+2↓, *iNOS↓, *COX2/PTGS2↓, *ROS↓, *Stroke↓, Apoptosis↑, MMP↓, Bcl-2↓, Casp3↑, Casp9↑, TumAuto↑, HSP90↑, ER Stress↑, Hif1a↓, TumMeta↓, angioG↓, Tf↓, MAPK↓, PI3K↓, Akt↓, β-catenin/ZEB1↓, TumCCA↑, FOXO3↓, mTOR↓,
7819- JG,    Evaluation of pharmacokinetic, biodistribution, pharmacodynamic, and toxicity profile of free juglone and its sterically stabilized liposomes
- vitro+vivo, Nor, NA
*Half-Life⇅, eff↑, eff↑, Dose↝,
1917- JG,    Inhibition of human leukemia cells growth by juglone is mediated via autophagy induction, endogenous ROS production, and inhibition of cell migration and invasion
- in-vitro, AML, HL-60
selectivity↑, LC3I↑, LC3II↑, Beclin-1/ATG6↑, ROS↑, tumCV↓, Dose↝, TumAuto↑,
4011- K+,    Sodium and potassium intakes among US adults: NHANES 2003–2008
- Analysis, NA, NA
*Dose↓, *eff↑, *BP↓,
4005- K+,    Potassium
- Review, Nor, NA - Review, Stroke, NA
*Risk↓, *Dose↝, *Risk↓, *BMD↑, *glucose↓,
8101- KAE,    Kaempferol inhibits cell proliferation and glycolysis in esophagus squamous cell carcinoma via targeting EGFR signaling pathway
- vitro+vivo, ESCC, KYSE150 - vitro+vivo, ESCC, Eca109
TumCCA↑, TumCP↓, Glycolysis↓, HK2↓, GlucoseCon↓, lactateProd↓, EGFR↓, TumCG↓, P21↑, Dose↝, Ki-67↓,
8103- KAE,    The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions
- in-vitro, HCC, HUH7
Dose↝, HIF-1↓, tumCV↓,
8058- KAE,    A randomized, placebo‐controlled trial evaluating the safety of excessive administration of kaempferol aglycone
- Trial, Nor, NA
*AntiBio↑, *antiOx↑, *Inflam↓, *AntiTum↑, *AntiDiabetic↑, *cardioP↑, *neuroP↑, *Dose↝, *toxicity↓,
8071- KAE,    Cellular reprogramming and signaling control by kaempferol in colorectal cancer
- Review, CRC, NA
*toxicity↓, Risk↓, MMPs↓, VEGF↓, VEGFR1↓, Wnt↓, β-catenin/ZEB1↑, PI3K↓, Akt↓, mTOR↓, ChemoSen↑, *BioAv↓, TumCCA↑, Apoptosis↑, Hif1a↓, ROS↑, TumCMig↓, TumMeta↓, PKM2↓, Glycolysis↓, DNAdam↑, HO-1↑, Ferroptosis↑, eff↑, Dose↝, BioAv↑,
8061- KAE,    Kaempferol induces apoptosis in ovarian cancer cells through activating p53 in the intrinsic pathway
- in-vitro, Ovarian, A2780S - in-vitro, Ovarian, OVCAR-3
TumCP↓, Apoptosis↑, Casp3↑, Casp7↑, Risk↓, VEGF↓, TumCP↓, Dose↝, P53↑,
8063- KAE,    Kaempferol exerts anti-proliferative effects on human ovarian cancer cells by inducing apoptosis, G0/G1 cell cycle arrest and modulation of MEK/ERK and STAT3 pathways
- in-vitro, Ovarian, NA
Dose↓, selectivity↑, Casp3↑, Casp8↑, Casp9↑, BAX↑, TumCCA↑, MEK↓, ERK↓, STAT3↓,
8064- KAE,    Kaempferol Inhibits Pancreatic Cancer Cell Growth and Migration through the Blockade of EGFR-Related Pathway In Vitro
- in-vitro, PC, MIA PaCa-2 - in-vitro, PC, PANC1 - in-vitro, PC, SNU-213
AntiCan↑, tumCV↓, Apoptosis↑, TumCMig↓, *toxicity↓, Dose?,
8074- KAE,    Dose-dependent tuning of HSP70-Beclin-1 by kaempferol governs autophagy and chemosensitivity
- in-vitro, SCC, KYSE150 - in-vitro, SCC, KYSE450 - in-vitro, CRC, HCT116 - in-vitro, Liver, HepG2 - in-vitro, Cerv, HeLa - in-vitro, Lung, A549
ChemoSen⇅, HSP70/HSPA5↑, Beclin-1/ATG6⇅, Dose↝, TumVol⇅, TumW⇅,
8079- KAE,    Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Kaempferol in Colorectal Cancer Cells
- in-vitro, CRC, DLD1 - in-vitro, Lung, A549 - in-vitro, Liver, HUH7 - in-vitro, Cerv, HeLa
*antiOx↑, *AntiBio↑, *AntiDiabetic↑, *AntiCan↑, Dose↝, TumCP↓, ER Stress↑, Apoptosis↑, Bcl-2↓, BAX↑, Casp3↑, Casp9↑, Casp12↝, NF-kB↓, P53↑,
8080- KAE,    Hepatoprotective Effect of Kaempferol—A Review
- Review, Nor, NA
*hepatoP↑, *SIRT1↑, *AMPK↑, *TLR4↓, *NF-kB↓, *GutMicro↑, *Dose↝, *BioAv↓, *BioAv↑, *CYP2E1↓, *lipidLev↓, *COX2/PTGS2↓, *IL1β↓, *TNF-α↓, *IL6↓, *NO↓, *PGE2↓, *iNOS↓, *SOD↑, *MDA↓, *ROS↓, *AST↓, *ALAT↓, *GSH↑, *SOD↑, *Cyt‑c↓, *BAX↓, *Casp3↓, *Casp8↓, *Casp9↓, *COL1↓, *p‑SMAD2↓, *p‑SMAD3↑, *α-SMA↓, *TGF-β↓, *P450↝, *P-gp/ABCB1↓, *BioEnh↑,
7827- KAE,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *Learn↑, *memory↑, *antiOx↑, *Inflam↓, *Aβ↓, *cognitive↑, *BDNF↑, *TrkB↑, *CREB↑, *ERβ/ESR2↑, *ERK↑, *ROS↓, *AChE↓, *Dose↑,
8109- L-Orn,    Effects of Oral Ingestion of L-Ornithine on Mental Stress and Fatigue Based on the Trier Social Stress Test in Healthy Humans: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial
- Trial, Nor, NA
*cortisol↓, *Stress↓, *Dose↝, *fatigue↓,
8110- L-Orn,    L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism
- Trial, Nor, NA
*Dose↝, *KeyT↝, *FFA/NEFA↝, *NH3↓, *fatigue↓,
8117- LA,  ProBio,    The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial
- Trial, CRC, NA
Dose↝, Inf↓, ZO-1↓, other↓,
8118- LA,  ProBio,    Randomised clinical trial: the effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery - a double-blind study
- Trial, CRC, NA
Inf↓, IBI↑, Dose↝, Diar↓,
8148- lamb,    Anti-Cancer Effect of Lambertianic Acid by Inhibiting the AR in LNCaP Cells
- in-vitro, Pca, LNCaP
*antiAll↑, *Bacteria↓, AR↓, PSA↓, TumCCA↑, CDK4↓, CDK6↓, cycD1/CCND1↓, P53↑, P21↑, p27/CDKN1B↓, Apoptosis↑, cl‑Casp9↑, cl‑Casp3↑, cl‑PARP↑, BAX↑, Bcl-2↓, Dose↝,
8174- Lap,    Lapatinib: a dual inhibitor of human epidermal growth factor receptor tyrosine kinases
EGFR↓, HER2/EBBR2↓, BioAv↝, eff↑, Dose↝,
8171- Lap,    Effects of food on the relative bioavailability of lapatinib in cancer patients
- Trial, Var, NA
BioAv↝, Dose↝,
8170- Lap,  capec,    A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses
- Trial, BC, NA
Dose↝, TTP↑, OS↑,
8162- LapC,    Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2
- in-vitro, Melanoma, MEL526 - in-vitro, Melanoma, MEL697 - in-vitro, Melanoma, MEL103
Glycolysis↓, OCR↑, PKM2↓, ATP↓, TumCP↓, Apoptosis↑, OXPHOS↑, Dose↝,
8177- Las,    Lasiokaurin Regulates PLK1 to Induce Breast Cancer Cell G2/M Phase Block and Apoptosis
- vitro+vivo, BC, MDA-MB-231
Dose↝, tumCV↓, Apoptosis↑, TumCCA↑, PLK1↓, CDC25↓, Akt↓,
8256- LCA,    Licochalcone A inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice
- in-vivo, Colon, CT26
TumVol?, TumCP↓, *RenoP↑, *creat↓, BUN↓, hepatoP↑, *ALAT↓, *AST↓, *NO↓, *lipid-P↓, *GSH↑, chemoP↑, Dose↝,
8209- LCA,    Licochalcone A Exerts Anti-Cancer Activity by Inhibiting STAT3 in SKOV3 Human Ovarian Cancer Cells
- in-vitro, Ovarian, SKOV3
tumCV↓, TumCCA↑, ROS↑, MMP↓, Apoptosis↑, cl‑Casp↑, Cyt‑c↑, STAT3↓, TumCP↓, Dose↝, p‑STAT3↓,
8216- LCA,    Effects of licochalcone A on the bioavailability and pharmacokinetics of nifedipine in rats: possible role of intestinal CYP3A4 and P-gp inhibition by licochalcone A
- in-vivo, Nor, NA
*Dose↝, *CYP3A4↓, *P-gp/ABCB1↓,
8219- LCA,    Licochalcone A Ameliorates Cognitive Dysfunction in an Alzheimer's Disease Model by Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis
- in-vivo, AD, NA
*Dose↝, *cognitive↑, *Aβ↓, *ER Stress↓, *BioAv↑, *toxicity↓, *PERK↓, *eIF2α↓, *ATF4↓, *CHOP/DDIT3↓, *NRF2↑,
8220- LCA,    Licochalcone a enhances cognitive resilience in APP/PS1 Mice by modulating glucose metabolism, Aβ burden, and neuroinflammation
- in-vivo, AD, NA
*Dose↝, *memory↑, *PSD95↑, *Ki-67↑, *GLUT1↑, *Aβ↓, *Aβ42↓, *Inflam↓, *TREM2↓, *cognitive↑,
8262- LE,    Phytochemical profiling, antimicrobial, cytotoxic and apoptotic effects of Glycyrrhiza glabra ethanolic extract
- in-vitro, Liver, HepG2
*Dose↝, *AntiBio↑, Dose↝, P53↑, BAX↑, Bcl-2↓, Apoptosis↑,
8263- LE,    Glycyrrhiza glabra L. suppress the proliferation of non-small cell lung cancer by inducing necrosis rather than apoptosis despite increasing bax level
- in-vitro, Lung, A549
BAX↑, necrosis↑, Dose↝,
8264- LE,  ISL,    Glycyrrhiza glabra L. Extracts with Potential Antiproliferative and Anti-Migration Activities Against Breast and Gynecological Cancer Cell Lines
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vitro, Melanoma, A2780S - in-vitro, Cerv, HeLa
eff↑, Dose↝, Dose↑,
8236- LE,    Licorice (Glycyrrhiza glabra L.)-Derived Phytochemicals Target Multiple Signaling Pathways to Confer Oncopreventive and Oncotherapeutic Effects
- Review, Var, NA
Bcl-2↓, CDK2↓, PI3K↓, cJun↓, mTOR↓, NF-kB↓, VEGF↓, MMP3↓, toxicity↓, Dose↑, chemoP↑, *antiOx↑, *Inflam↓, Dose↝, *COX2/PTGS2↓, *iNOS↓, *IL6↓, *IL10↓, *PGE2↓, *IκB?, *NRF2↑, *HO-1↑, *lipid-P↓, *ROS↓, *Catalase↑, *GPx↑, *SOD↑, Apoptosis↑, ROS↑, TumCP↓, TumCCA↑, cycE/CCNE↓, cycD1/CCND1↓, p‑GSK‐3β↓, PI3K↓, MKK4↓, MKK7↓, HSP90↓, LC3‑Ⅱ/LC3‑Ⅰ↑, Beclin-1/ATG6↑, p62↓, p‑Akt↓, cl‑Casp9↑, cl‑Casp7↑, cl‑Casp3↑, cl‑PARP↑, BAX↑, Cyt‑c↑, P53↑, STAT3↓, E-cadherin↑, Vim↓, N-cadherin↓, CD31/PECAM-1↓, Hif1a↓, iNOS↓, DNAdam↑, MMP↓, BIM↑, APAF1↑, PCNA↓, toxicity↝, eff↑,
8181- LEC,  CUR,    Soybean lecithin-stabilized oil-in-water (O/W) emulsions increase the stability and in vitro bioaccessibility of bioactive nutrients
- in-vitro, Nor, NA
*BioEnh↑, *Dose↝,
8145- LF,    Neuroprotective Effects of Lactoferrin in Alzheimer's and Parkinson's Diseases: A Narrative Review
- Review, AD, NA - Review, Park, NA
*AntiBio↑, *Imm↑, *AntiCan↑, *neuroP↑, *BBB↑, *APOE4↓, *ROS↓, *Inflam↓, *Apoptosis↓, *Learn↑, *memory↑, *ADAM10↑, *PSEN1/PS1↑, *cl‑APP↑, *BACE/β-secretase↓, *cognitive↑, *MDA↓, *IL6↓, *TNF-α↓, *neuroP↑, *Dose↝, *IronCh↑, *SOD↑, *BioAv↝,
8123- LF,    Effect of orally administered bovine lactoferrin on the growth of adenomatous colorectal polyps in a randomized, placebo-controlled clinical trial
- Trial, CRC, NA
AntiCan↑, Dose↝, APG↓,
8124- LF,    Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine
- Trial, CRC, NA
Risk↓, Dose↝, NK cell↑, Neut↑, CD4+↑, Imm↑, APG↓,
8125- LF,    Talactoferrin alfa versus placebo in patients with refractory advanced non-small-cell lung cancer (FORTIS-M trial)
- Trial, NSCLC, NA
Dose?, eff∅,
8126- LF,    Randomized, double-blind, placebo-controlled phase II study of single-agent oral talactoferrin in patients with locally advanced or metastatic non-small-cell lung cancer that progressed after chemotherapy
- NA, NSCLC, NA
Dose↝, OS↑, PFS↑, DCR↑, other↝,
8127- LF,    Phase I trial of oral talactoferrin alfa in refractory solid tumors
- Trial, Var, NA
Imm↑, NK cell↑, Dose↝, toxicity↓, IL18↑, SD↑, TumCG↓, OS↑,
8128- LF,    Phase 2 trial of talactoferrin in previously treated patients with metastatic renal cell carcinoma
- Trial, RCC, NA
Imm↑, NK cell↑, Dose↝, toxicity↓, PFS↑,
8129- LF,    Study on the Therapeutic Benefit on Lactoferrin in Patients with Colorectal Cancer Receiving Chemotherapy
- Trial, CRC, NA
Dose↝, toxicity↓, INF-γ↝, other↑, *ROS↓, Imm↑, WBC↑, Neut↑, T-Cell↑, *antiOx↑, *GSH↑, *chemoP↑, *RenoP↑, *hepatoP↑, BUN↓, creat↓, ALAT↓, AST↓, RBC↑, PC↑, Mucositis↓, *AntiBio↑, *AntiViral↑, *AntiFungal↑, *Inflam↓,
8144- LF,    A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae: Impact of the p-Akt/PTEN pathway
- Human, AD, NA
*Ach↑, *5HT↑, *TAC↑, *Inflam↓, *Akt↑, *PI3K↑, *Aβ42↓, *LDL↓, *ROS↓, *IL6↓, *HSP90↓, *Casp3↓, *tau↓, *MAPK↓, *PTEN↓, *cognitive↑, *Dose↝,
8142- LF,    A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults
- Trial, Nor, NA
*Dose↝, *toxicity↓,
8200- LGE,    Chemical Properties and Therapeutic Potential of Citral, a Monoterpene Isolated from Lemongrass
- Review, Var, NA
*AntiBio↑, *antiOx↑, *AntiCan↑, *AntiDiabetic↑, *Inflam↓, Dose↝, BioAv↝,
8199- LGE,    Citral is a new inducer of caspase-3 in tumor cell lines
Dose↑, Apoptosis↑, DNAdam↑, Casp3↑,
8195- LGE,    In Vivo Anti-Tumor Effects of Citral on 4T1 Breast Cancer Cells via Induction of Apoptosis and Downregulation of Aldehyde Dehydrogenase Activity
- vitro+vivo, BC, 4T1
TumCD↑, Dose↝, TumVol↓, cl‑Casp3↑, β-catenin/ZEB1↑, ALDH↓, Wnt↓,

Showing Research Papers: 701 to 750 of 1061
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1061

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

ACE/ACE1↓, 1,   APG↓, 2,   DCR↑, 1,   Mucositis↓, 1,   PC↑, 1,   PFS↑, 2,   RBC↑, 1,   TTP↑, 1,   WBC↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Ferroptosis↑, 1,   HO-1↑, 1,   OXPHOS↑, 1,   ROS↑, 4,  

Metal & Cofactor Biology(tgid=2) ⓘ

Tf↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   CDC25↓, 1,   MEK↓, 1,   MKK4↓, 1,   MKK7↓, 1,   MMP↓, 3,   OCR↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   BUN↓, 2,   GlucoseCon↓, 1,   Glycolysis↓, 3,   HK2↓, 1,   lactateProd↓, 1,   PKM2↓, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   p‑Akt↓, 1,   APAF1↑, 1,   Apoptosis↑, 12,   BAX↑, 6,   Bcl-2↓, 5,   BIM↑, 1,   cl‑Casp↑, 1,   Casp12↝, 1,   Casp3↑, 5,   cl‑Casp3↑, 3,   Casp7↑, 1,   cl‑Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 3,   cl‑Casp9↑, 2,   Cyt‑c↑, 2,   Ferroptosis↑, 1,   iNOS↓, 1,   MAPK↓, 1,   necrosis↑, 1,   p27/CDKN1B↓, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 1,   other↓, 1,   other↑, 1,   other↝, 1,   SD↑, 1,   tumCV↓, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 2,   HSP70/HSPA5↑, 1,   HSP90↓, 1,   HSP90↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 2,   Beclin-1/ATG6⇅, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3I↑, 1,   LC3II↑, 1,   p62↓, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 3,   P53↑, 5,   cl‑PARP↑, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   P21↑, 2,   PLK1↓, 1,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   ERK↓, 1,   FOXO3↓, 1,   p‑GSK‐3β↓, 1,   mTOR↓, 3,   PI3K↓, 4,   STAT3↓, 3,   p‑STAT3↓, 1,   TumCG↓, 2,   Wnt↓, 2,  

Migration(tgid=13) ⓘ

Ca+2↓, 1,   CD31/PECAM-1↓, 1,   E-cadherin↑, 1,   Ki-67↓, 1,   MMP3↓, 1,   MMPs↓, 1,   N-cadherin↓, 1,   TumCMig↓, 2,   TumCP↓, 8,   TumMeta↓, 2,   VEGFR1↓, 1,   Vim↓, 1,   ZO-1↓, 1,   β-catenin/ZEB1↓, 1,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   EGFR↓, 2,   HIF-1↓, 1,   Hif1a↓, 3,   VEGF↓, 3,  

Barriers & Transport(tgid=15) ⓘ

IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   IL18↑, 1,   Imm↑, 4,   INF-γ↝, 1,   Neut↑, 2,   NF-kB↓, 2,   NK cell↑, 3,   PSA↓, 1,   T-Cell↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   BioAv↝, 3,   ChemoSen↑, 1,   ChemoSen⇅, 1,   Dose?, 2,   Dose↓, 1,   Dose↑, 3,   Dose↝, 31,   eff↑, 6,   eff∅, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AR↓, 1,   AST↓, 1,   creat↓, 1,   EGFR↓, 2,   HER2/EBBR2↓, 1,   Ki-67↓, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   chemoP↑, 2,   chemoPv↑, 1,   hepatoP↑, 1,   OS↑, 3,   Risk↓, 3,   toxicity↓, 4,   toxicity↝, 1,   TumVol?, 1,   TumVol↓, 1,   TumVol⇅, 1,   TumW⇅, 1,  

Infection & Microbiome(tgid=24) ⓘ

Diar↓, 1,   Inf↓, 2,  
Total Targets: 155

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

antiAll↑, 1,   AntiBio↑, 6,   APOE4↓, 1,   Aβ42↓, 2,   FFA/NEFA↝, 1,   Learn↑, 2,   PSEN1/PS1↑, 1,   Stress↓, 1,   Stroke↓, 1,   TREM2↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 6,   Catalase↑, 1,   CYP2E1↓, 1,   GPx↑, 1,   GSH↑, 3,   HO-1↑, 1,   lipid-P↓, 2,   MDA↓, 2,   NRF2↑, 2,   ROS↓, 7,   SOD↑, 4,   TAC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   AMPK↑, 1,   CREB↑, 1,   CYP3A4↓, 1,   glucose↓, 1,   KeyT↝, 1,   LDL↓, 1,   lipidLev↓, 1,   NH3↓, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Apoptosis↓, 1,   BAX↓, 1,   Casp3↓, 2,   Casp8↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   iNOS↓, 3,   MAPK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   eIF2α↓, 1,   ER Stress↓, 1,   HSP90↓, 1,   PERK↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   PI3K↑, 1,   PTEN↓, 1,  

Migration(tgid=13) ⓘ

cl‑APP↑, 1,   COL1↓, 1,   Ki-67↑, 1,   p‑SMAD2↓, 1,   p‑SMAD3↑, 1,   TGF-β↓, 1,   α-SMA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↓, 1,   NO↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GLUT1↑, 1,   P-gp/ABCB1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 3,   IL10↓, 1,   IL1β↓, 1,   IL6↓, 4,   Imm↑, 1,   Inflam↓, 8,   IκB?, 1,   NF-kB↓, 1,   PGE2↓, 2,   TLR4↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 1,   ADAM10↑, 1,   BDNF↑, 1,   PSD95↑, 1,   tau↓, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 3,   BACE/β-secretase↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

cortisol↓, 1,   ERβ/ESR2↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 2,   BioEnh↑, 2,   Dose↓, 1,   Dose↑, 1,   Dose↝, 14,   eff↑, 1,   Half-Life⇅, 1,   Half-Life↝, 1,   P450↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 2,   BMD↑, 1,   BP↓, 1,   creat↓, 1,   GutMicro↑, 1,   IL6↓, 4,   Ki-67↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiDiabetic↑, 3,   AntiTum↑, 1,   cardioP↑, 1,   chemoP↑, 1,   cognitive↑, 5,   fatigue↓, 2,   hepatoP↑, 2,   memory↑, 3,   neuroP↑, 4,   RenoP↑, 2,   Risk↓, 2,   toxicity↓, 5,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 1,   Bacteria↓, 1,  
Total Targets: 120

Scientific Paper Hit Count for: Dose, Dosage
39 Magnetic Fields
31 Selenium NanoParticles
27 Hydrogen Gas
24 Radiotherapy/Radiation
22 Curcumin
19 Silver-NanoParticles
19 Resveratrol
19 Chemotherapy
17 Vitamin C (Ascorbic Acid)
16 EGCG (Epigallocatechin Gallate)
16 Selenium
16 Selenite (Sodium)
15 Ginkgo biloba-EGb 761
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Chlorogenic acid
12 Carvacrol
12 Ginger/6-Shogaol/Gingerol
12 Inositol
12 Kaempferol
11 buckwheat sprouts
11 Choline
11 Ellagic acid
11 Sulforaphane (mainly Broccoli)
11 Folic Acid, Vit B9
11 Hyperthermia
10 isoquercitrin
10 Lycopene
10 Hydroxycinnamic-acid
10 Lemongrass Extract/Citral
10 Lactoferrin/Talactoferrin
9 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
9 Baicalein
9 Dichloroacetate
9 Exercise
9 itraconazole
9 Magnetic Field Rotating
8 Rutin
8 Auranofin
8 Melatonin
8 Citric Acid
8 Dandelion Root
8 Ferulic acid
8 Fenbendazole
8 Fisetin
8 Fucoidan
8 Ginkgo biloba
8 Ginkgetin
8 HydroxyTyrosol
8 Silymarin (Milk Thistle) silibinin
7 3-bromopyruvate
7 α-Bisabolol / Chamomile oil
7 Quercetin
7 Mung Bean Sprouts
7 Capsaicin
7 Centella asiatica / Gotu kola → asiaticoside
7 chitosan
7 Echinacea
7 Electrical Pulses
7 Formononetin
7 Gamma-aminobutyric acid
7 Genistein (soy isoflavone)
7 Hibiscus sabdariffa
7 Indole-3-carbinol
7 Thymoquinone
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Metformin
6 Aspirin
6 Astaxanthin
6 Vitexin
6 Caffeic acid
6 immunotherapy
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Eugenol
6 Ivermectin
6 Vitamin D3
6 Honokiol
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 iodine
6 Inulin Prebiotic
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Cynara scolymus/Globe Artichoke/Artichoke Extract
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Paclitaxel/Taxol
5 Boron
5 isoorientin
5 Isovitexin
5 Chocolate
5 Spermidine
5 Oxygen, Hyperbaric
5 diet FMD Fasting Mimicking Diet
5 Vitamin B12
5 Gossypol/AT-101
5 Grapeseed extract
5 Isoliquiritigenin
5 Licorice
5 isoflavones
5 Licochalcone A
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 EMF
5 Rosmarinic acid
5 VitK3,menadione
4 cetuximab
4 Cisplatin
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Celastrol
4 Chrysin
4 Chyawanprash
4 Cichoric acid / Chicoric acid
4 Coenzyme Q10
4 HydroxyCitric Acid
4 Garcinol
4 Diclofenac
4 Docosahexaenoic Acid
4 eicosapentaenoic acid
4 Shilajit/Fulvic Acid
4 Gallic acid
4 capecitabine
4 probiotics
4 Propyl gallate
3 Astragalus
3 Fennel Oil/Foeniculum vulgare
3 Angelica archangelica / Garden Angelica
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Beta-Caryophyllene
3 Bromelain
3 borneol
3 Cat’s Claw
3 chaetocin
3 doxorubicin
3 Calorie Restriction Mimetics
3 Crocetin
3 Dasatinib/Phyrago
3 Disulfiram
3 Eurycomanone
3 Silicic Acid
3 Gambogic Acid
3 Huperzine A/Huperzia serrata
3 Isobavachalcone
3 Lapatinib
3 metronomic chemo
3 Methylsulfonylmethane
3 Oleuropein
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Turmerones
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 1,8-Cineole
2 Photodynamic Therapy
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 DTS(dibenzyl trisulphide) from Anamu
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Bortezomib
2 Lecithin
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 Cynaropicrin
2 diet Plant based
2 diet Short Term Fasting
2 D-limonene
2 Emodin
2 5-fluorouracil
2 Evodiamine
2 Vitamin B6,pyridoxine
2 Flickering Light Stimulation
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Germanium inorganic
2 Geraniol
2 Ginkgolide B
2 Gold NanoParticles
2 Germacranolide sesquiterpene lactone
2 Helleborus niger extracts – Christmas Rose
2 Recombinant Methioninase
2 Juglone
2 Potassium
2 L-ornithine
2 Lactobacillus
2 Luteolin
2 nivolumab
2 Iron
2 Niclosamide (Niclocide)
2 Bifidobacterium
2 Phosphatidylserine
2 Rauwolfia serpentina/Indian Snakeroot
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Annona atemoya Leaf Extract
1 Anethole/trans-Anethole
1 Acer okamotoanum
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 brusatol
1 Bruteridin(bergamot juice)
1 Black Seed Oil/Nigella sativa
1 urea
1 Catechins
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Chlorophyllin
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 CUSP9
1 Cysteamine
1 diet Ketogenic
1 Dipyridamole
1 Docetaxel
1 Zinc
1 Protocatechuic acid
1 Estragole
1 Aluminum
1 ferumoxytol
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Arsenic trioxide
1 Vitamin A, Retinoic Acid
1 Bifidobacterium animalis subsp. lactis GCL2505
1 Glabrescione B
1 carboplatin
1 Graviola
1 hydrogen sulfide
1 High-Ozonide Oil
1 Hormone replacement therapy
1 Hyperoside
1 Extracorporeal Shock Wave Therapy
1 Anthocyanins
1 Gemcitabine (Gemzar)
1 lambertianic acid
1 Lapachol
1 Lasiodin
1 MCToil
1 Sulodexide
1 magnetic nanoparticles
1 Mistletoe/Viscum album Extracts
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 ipilimumab
1 Aidi injection
1 Phenolic Acids
1 Polyphenols
1 alpha Linolenic acid
1 Pterostilbene
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 Sinapic acid
1 salinomycin
1 α-Santalol/Sandalwood oil
1 Sulfasalazine
1 irinotecan
1 Terpinen-4-ol / Tea Tree Oil
1 Taurine
1 Triphala
1 triptolide
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vanillic Acid
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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