| 6174- | TM, | Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse |
| - | Trial, | BC, | NA |
| 6173- | TM, | Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study |
| - | Trial, | Var, | NA |
| 6172- | TM, | Phase II trial of copper depletion with tetrathiomolybdate as an antiangiogenesis strategy in patients with hormone-refractory prostate cancer |
| - | Trial, | Pca, | NA |
| 2373- | TMZ, | The role of pyruvate kinase M2 in anticancer therapeutic treatments |
| - | Review, | Var, | NA |
| 139- | Tomatine, | CUR, | Combination of α-Tomatine and Curcumin Inhibits Growth and Induces Apoptosis in Human Prostate Cancer Cells |
| - | in-vitro, | Pca, | PC3 |
| 113- | TQ, | Selective Targeting of the Hedgehog Signaling Pathway by PBM Nanoparticles in Docetaxel-Resistant Prostate Cancer |
| - | vitro+vivo, | Pca, | C4-2B |
| 962- | TQ, | Thymoquinone affects hypoxia-inducible factor-1α expression in pancreatic cancer cells via HSP90 and PI3K/AKT/mTOR pathways |
| - | in-vitro, | PC, | PANC1 | - | in-vitro, | Nor, | hTERT-HPNE | - | in-vitro, | PC, | AsPC-1 | - | in-vitro, | PC, | Bxpc-3 |
| 1138- | TQ, | Thymoquinone inhibits epithelial-mesenchymal transition in prostate cancer cells by negatively regulating the TGF-β/Smad2/3 signaling pathway |
| - | in-vitro, | Pca, | DU145 | - | in-vitro, | Pca, | PC3 |
| 1052- | TQ, | Thymoquinone Anticancer Effects Through the Upregulation of NRF2 and the Downregulation of PD-L1 in MDA-MB-231 Triple-Negative Breast Cancer Cells |
| - | in-vitro, | BC, | MDA-MB-231 |
| 1019- | TQ, | Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation |
| - | vitro+vivo, | CRC, | LoVo |
| 2353- | TQ, | The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies |
| - | Review, | PC, | NA |
| 5221- | TQ, | Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells |
| - | in-vitro, | AML, | HL-60 |
| 5222- | TQ, | Thymoquinone chemosensitizes colon cancer cells through inhibition of NF-κB |
| - | in-vitro, | CRC, | COLO205 | - | in-vitro, | CRC, | HCT116 |
| 1309- | TQ, | QC, | Thymoquinone and quercetin induce enhanced apoptosis in non-small cell lung cancer in combination through the Bax/Bcl2 cascade |
| - | in-vitro, | Lung, | NA |
| 1308- | TQ, | Thymoquinone induces apoptosis via targeting the Bax/BAD and Bcl-2 pathway in breast cancer cells |
| - | in-vitro, | BC, | MCF7 |
| 1937- | TQ, | Migration and Proliferation Effects of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) and Thymoquinone (TQ) on In Vitro Wound Healing Models |
| - | NA, | Nor, | 3T3 |
| 1928- | TQ, | Thymoquinone Crosstalks with DR5 to Sensitize TRAIL Resistance and Stimulate ROS-Mediated Cancer Apoptosis |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 1929- | TQ, | Thymoquinone Suppresses the Proliferation, Migration and Invasiveness through Regulating ROS, Autophagic Flux and miR-877-5p in Human Bladder Carcinoma Cells |
| - | in-vitro, | Bladder, | 5637 | - | in-vitro, | Bladder, | T24/HTB-9 |
| 1930- | TQ, | Therapeutic implications and clinical manifestations of thymoquinone |
| - | Review, | Var, | NA |
| 1931- | TQ, | doxoR, | Thymoquinone enhances the anticancer activity of doxorubicin against adult T-cell leukemia in vitro and in vivo through ROS-dependent mechanisms |
| - | in-vivo, | AML, | NA |
| 1932- | TQ, | Recent Findings on Thymoquinone and Its Applications as a Nanocarrier for the Treatment of Cancer and Rheumatoid Arthritis |
| - | Review, | Var, | NA |
| 1933- | TQ, | Thymoquinone: potential cure for inflammatory disorders and cancer |
| - | Review, | Var, | NA |
| 1934- | TQ, | Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species |
| - | in-vitro, | Pca, | PC3 | - | in-vitro, | Pca, | C4-2B |
| 1935- | TQ, | Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis |
| - | Review, | OS, | NA |
| 1936- | TQ, | Thymoquinone induces apoptosis and increase ROS in ovarian cancer cell line |
| - | in-vitro, | Ovarian, | CaOV3 | - | in-vitro, | Nor, | WRL68 |
| 2125- | TQ, | Thymoquinone Selectively Kills Hypoxic Renal Cancer Cells by Suppressing HIF-1α-Mediated Glycolysis |
| - | in-vitro, | RCC, | RCC4 | - | in-vitro, | RCC, | Caki-1 |
| 2112- | TQ, | Crude flavonoid extract of the medicinal herb Nigella sativa inhibits proliferation and induces apoptosis in breastcancer cells |
| - | in-vitro, | BC, | MCF7 |
| 2124- | TQ, | Thymoquinone: an emerging natural drug with a wide range of medical applications |
| - | Review, | Var, | NA |
| 2123- | TQ, | Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma |
| - | in-vitro, | lymphoma, | PEL |
| 2122- | TQ, | Review on Molecular and Therapeutic Potential of Thymoquinone in Cancer |
| - | Review, | Var, | NA |
| 2121- | TQ, | Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 2120- | TQ, | Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3 |
| - | in-vitro, | Melanoma, | A431 |
| 2119- | TQ, | Dual properties of Nigella Sativa: anti-oxidant and pro-oxidant |
| - | Review, | Var, | NA |
| 2118- | TQ, | Rad, | In vivo radioprotective effects of Nigella sativa L oil and reduced glutathione against irradiation-induced oxidative injury and number of peripheral blood lymphocytes in rats |
| - | in-vivo, | Nor, | NA |
| 2117- | TQ, | Effects of Nigella sativa L. on Lipid Peroxidation and Reduced Glutathione Levels in Erythrocytes of Broiler Chickens |
| - | in-vivo, | Nor, | NA |
| 2116- | TQ, | Cisplatin, | Oral administration of Nigella sativa oil ameliorates the effect of cisplatin on membrane enzymes, carbohydrate metabolism and oxidative damage in rat liver |
| - | in-vivo, | Nor, | NA |
| 2115- | TQ, | Protective effects of Nigella sativa on gamma radiation-induced jejunal mucosal damage in rats |
| - | in-vivo, | Nor, | NA |
| 2114- | TQ, | Anti-Aging Effect of Nigella Sativa Fixed Oil on D-Galactose-Induced Aging in Mice |
| - | in-vivo, | Nor, | NA |
| 2113- | TQ, | Potential role of Nigella sativa (NS) in abating oxidative stress-induced toxicity in rats: a possible protection mechanism |
| - | in-vivo, | Nor, | NA |
| 2126- | TQ, | Biological and therapeutic activities of thymoquinone: Focus on the Nrf2 signaling pathway |
| - | Review, | Nor, | NA |
| 2127- | TQ, | Therapeutic Potential of Thymoquinone in Glioblastoma Treatment: Targeting Major Gliomagenesis Signaling Pathways |
| - | Review, | GBM, | NA |
| 2128- | TQ, | Thymoquinone inhibits phorbol ester-induced activation of NF-κB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo |
| - | in-vivo, | NA, | NA |
| 2129- | TQ, | doxoR, | Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells |
| - | in-vitro, | BC, | MCF7 |
| 2130- | TQ, | Thymoquinone Attenuates Brain Injury via an Anti-oxidative Pathway in a Status Epilepticus Rat Model |
| - | in-vivo, | Nor, | NA |
| 2131- | TQ, | Therapeutic impact of thymoquninone to alleviate ischemic brain injury via Nrf2/HO-1 pathway |
| - | in-vitro, | Stroke, | NA | - | in-vivo, | Nor, | NA |
| 2132- | TQ, | Thymoquinone treatment modulates the Nrf2/HO-1 signaling pathway and abrogates the inflammatory response in an animal model of lung fibrosis |
| - | in-vivo, | Nor, | NA |
| 2133- | TQ, | CUR, | Cisplatin, | Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling |
| - | in-vitro, | Nor, | HEK293 | - | in-vivo, | NA, | NA |
| 2134- | TQ, | Modulation of Nrf2/HO1 Pathway by Thymoquinone to Exert Protection Against Diazinon-induced Myocardial Infarction in Rats |
| - | in-vivo, | Nor, | NA |
| 2135- | TQ, | Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets |
| - | in-vitro, | Nor, | HaCaT |
| 2136- | TQ, | Nigella sativa and thymoquinone suppress cyclooxygenase-2 and oxidative stress in pancreatic tissue of streptozotocin-induced diabetic rats |
| - | in-vivo, | Nor, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
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