Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
2427- Wog,    Anti-cancer natural products isolated from chinese medicinal herbs
- Review, Var, NA
NO↓, PGE2↓, COX2/PTGS2↓, Ca+2↑, mtDam↑, *toxicity↓, eff↑, eff↓,
2301- Wog,    Flavonoids Targeting HIF-1: Implications on Cancer Metabolism
- Review, Var, NA
HK2↓, PDK1 / PDPK1↓, LDHA↓, Hif1a↓, PI3K↓, Akt↓, Glycolysis↓, P53↑, GLUT1↓,
2621- Wog,    Natural compounds targeting glycolysis as promising therapeutics for gastric cancer: A review
- Review, Var, NA
Hif1a↓, MCT4↓, LDH↓, lactateProd↓, ECAR↓, TumCP↓, Glycolysis↓,
2397- Wor,    Phytochemicals targeting glycolysis in colorectal cancer therapy: effects and mechanisms of action
- Review, Var, NA
lactateProd↓, GlucoseCon↓, GLUT3↓, HK2↓, PKM2↓, LDHA↓,
5015- Xan,  PEITC,    Comparison of the Impact of Xanthohumol and Phenethyl Isothiocyanate and Their Combination on Nrf2 and NF-κB Pathways in HepG2 Cells In Vitro and Tumor Burden In Vivo
- in-vitro, HCC, HepG2
NRF2↓, ROS↑, NF-kB↓, COX2/PTGS2↓, Apoptosis↑, NRF2↑, SOD↑, NQO1↑,
1913- Xyl,    Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer
- in-vivo, Oral, NA
TumVol↓, OS↑, PFK↓, toxicity↓, Dose∅, Ki-67↓,
1221- Z,    Unexpected zinc dependency of ferroptosis: what is in a name?
- Analysis, Nor, NA
*Ferroptosis↑, *ROS↑, *lipid-P↑,
1222- Z,    Zinc regulates primary ovarian tumor growth and metastasis through the epithelial to mesenchymal transition
- in-vitro, Ovarian, NA
EMT↑, TumCMig↑, TumCI↑, ERK↑, Akt↑,
4196- Z,    The effect of zinc supplementation on brain derived neurotrophic factor: A meta-analysis
- Review, NA, NA
*BDNF∅,
4197- Z,    The Effect of Zinc Supplementation on Circulating Levels of Brain-Derived Neurotrophic Factor (BDNF): A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Review, NA, NA
*BDNF↑, *other↓, *eff↑, *Inflam↓, *antiOx↑,
4084- Z,    Role of micronutrients in Alzheimer's disease: Review of available evidence
- Review, AD, NA
*neuroP↑, *cognitive↑, *AChE↓, *memory↑,
4166- Z,    Zinc monotherapy increases serum brain-derived neurotrophic factor (BDNF) levels and decreases depressive symptoms in overweight or obese subjects: a double-blind, randomized, placebo-controlled trial
- Trial, Obesity, NA
*BDNF↑, *Mood↑,
4165- Z,    Antidepressant-like activity of zinc: further behavioral and molecular evidence
- in-vivo, AD, NA
*BDNF↑,
4164- Z,    Zinc treatment induces cortical brain-derived neurotrophic factor gene expression
- Review, AD, NA
*BDNF↑,
961- Z,    Zinc Downregulates HIF-1α and Inhibits Its Activity in Tumor Cells In Vitro and In Vivo
- in-vitro, RCC, RCC4 - vitro+vivo, GBM, U373MG - in-vitro, Nor, HUVECs
Hif1a↓, HIF-1↓, VEGF↓, TumCI↓,
4191- Zeax,  Lut,    Effects of macular xanthophyll supplementation on brain-derived neurotrophic factor, pro-inflammatory cytokines, and cognitive performance
- Trial, AD, NA
*BDNF↑, *IL1β↓, *cognitive↑, *memory↑,
4890- ZER,    Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite
- in-vitro, Nor, RAW264.7
*iNOS↓, *COX2/PTGS2↓, *EP2↓, TumCP↓, selectivity↑, Apoptosis↑, *chemoP↑, *Inflam↓,
4889- ZER,    Zerumbone reduces proliferation of HCT116 colon cancer cells by inhibition of TNF-alpha
- in-vitro, CRC, HCT116
TumCP↓, TNF-α↓, *toxicity↝,
4888- ZER,  5-FU,    Modulation of the tumor microenvironment by zerumbone and 5-fluorouracil in colorectal cancer by target in cancer-associated fibroblasts
- in-vitro, CRC, CT26
TumVol↓, *tumCV↓, survivin↓, β-catenin/ZEB1↓, Vim↓,
4887- ZER,  Rad,  Cisplatin,    Zerumbone acts as a radiosensitizer in head and neck squamous cell carcinoma
- in-vitro, HNSCC, CAL27
Apoptosis↑, ChemoSen↑, RadioS↑, tumCV↓,
4886- ZER,    Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio
- in-vitro, Liver, HepG2
TumCP↓, Apoptosis↑, BAX↑, Bcl-2↓, *selectivity↑,
4882- ZER,    An update of Nrf2 activators and inhibitors in cancer prevention/promotion
- Review, Var, NA
*Nrf1↑,
4885- ZER,    Anti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives
- Review, Var, NA
AntiTum↑, *Imm↑, AntiCan↑,
604- ZO,    Plant-Mediated Zinc Oxide Nanoparticles: Advances in the New Millennium towards Understanding Their Therapeutic Role in Biomedical Applications
- Review, NA, NA
ROS↑, Apoptosis↑, DNAdam↑,
2414- β‐Ele,    Beta‐elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7 - in-vivo, NA, NA
TumCMig↓, TumCI↓, TumMeta↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, PKM2↓, EGFR↓, GLUT1↓, LDHA↓, ECAR↓, OCR↓,
2425- γ-Toc,    Anticancer Effects of γ-Tocotrienol Are Associated with a Suppression in Aerobic Glycolysis
- in-vitro, NA, MCF7 - in-vivo, NA, NA
TumCG↓, GlucoseCon↓, ATP↓, lactateProd↓, Glycolysis↓, HK2↓, PFK↓, PKM2↓, LDHA↓, Akt↓, p‑mTOR↓, cMyc↓,

Showing Research Papers: 8251 to 8276 of 8276
Prev Page 166 of 166

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8276

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↑, 2,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   mtDam↑, 1,   OCR↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,   ECAR↓, 2,   GlucoseCon↓, 3,   Glycolysis↓, 4,   HK2↓, 3,   lactateProd↓, 4,   LDH↓, 1,   LDHA↓, 4,   MCT4↓, 1,   PDK1 / PDPK1↓, 1,   PFK↓, 2,   PKM2↓, 3,  

Cell Death(tgid=5) ⓘ

Akt↓, 2,   Akt↑, 1,   Apoptosis↑, 5,   BAX↑, 1,   Bcl-2↓, 1,   survivin↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   P53↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↑, 1,   ERK↑, 1,   p‑mTOR↓, 1,   PI3K↓, 1,   TumCG↓, 1,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   Ki-67↓, 1,   TumCI↓, 2,   TumCI↑, 1,   TumCMig↓, 1,   TumCMig↑, 1,   TumCP↓, 4,   TumMeta↓, 1,   Vim↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

EGFR↓, 1,   HIF-1↓, 1,   Hif1a↓, 3,   NO↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 2,   GLUT3↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   NF-kB↓, 1,   PGE2↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   Dose∅, 1,   eff↓, 1,   eff↑, 1,   RadioS↑, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   Ki-67↓, 1,   LDH↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 1,   OS↑, 1,   toxicity↓, 1,   TumVol↓, 2,  
Total Targets: 69

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Ferroptosis↑, 1,   lipid-P↑, 1,   Nrf1↑, 1,   ROS↑, 1,  

Cell Death(tgid=5) ⓘ

Ferroptosis↑, 1,   iNOS↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   tumCV↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EP2↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IL1β↓, 1,   Imm↑, 1,   Inflam↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↑, 5,   BDNF∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff↑, 1,   selectivity↑, 1,  

Functional Outcomes(tgid=23) ⓘ

chemoP↑, 1,   cognitive↑, 2,   memory↑, 2,   Mood↑, 1,   neuroP↑, 1,   toxicity↓, 1,   toxicity↝, 1,  
Total Targets: 26

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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