eff Cancer Research Results

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Scientific Papers found: Click to Expand⟱
1966- GamB,  Cisplatin,    Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling
- in-vitro, Lung, A549 - in-vitro, Lung, NCIH1299
TumCCA↑, PARP↑, eff↑, ROS↑, ChemoSen↑,
1970- GamB,    Gambogic acid-induced autophagy in nonsmall cell lung cancer NCI-H441 cells through a reactive oxygen species pathway
- NA, Lung, NCI-H441
TumCG↓, TumAuto↑, Beclin-1/ATG6↑, LC3‑Ⅱ/LC3‑Ⅰ↑, ROS↑, eff↓,
1971- GamB,    Gambogic acid triggers vacuolization-associated cell death in cancer cells via disruption of thiol proteostasis
- in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-435 - in-vitro, BC, MDA-MB-468 - in-vivo, NA, NA
Paraptosis↑, ER Stress↑, MMP↓, eff↓, selectivity↑, p‑ERK↑, p‑JNK↑, eff↓,
1972- GamB,  doxoR,    Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression
- in-vitro, BC, NA
eff↑, P-gp/ABCB1↓, ROS↑, survivin↓, p38↑,
7060- GamB,    New targets for the antitumor activity of gambogic acid in hematologic malignancies
- Review, Melanoma, RPMI-8226
AntiCan↑, TumCP↓, Apoptosis↑, SRC3↓, DIDO1/DIO-1↑, KCNH2/hERG↓, ROS↑, Bcl-2↓, P53↑, cMyc↓, VEGF↓, Casp3↑, cl‑PARP1↑, eff↓,
7087- GAR,    Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential
- Review, Var, NA
HATs↓, p300↓, CBP↓, NF-kB↓, STAT3↓, PI3K↓, Akt↓, MAPK↓, Wnt↓, β-catenin/ZEB1↓, Inflam↓, angioG↓, TumCP↓, TumMeta↓, TumCCA↑, EMT↓, CSCs↓, P53↑, TrxR↓, ROS↑, JNK↑, DNAdam↑, mt-Apoptosis↑, ER Stress↑, CHOP/DDIT3↑, DDIT4↑, TRIB3↑, SESN2↑, miR-218↑, eff↑, ChemoSen↑, BioAv↓, Half-Life↓, BioAv↑,
7092- GAR,    Garcinol and Its Role in Chronic Diseases
- Review, Var, NA
antiOx↑, Inflam↓, AntiCan↑, NF-kB↓, STAT3↓, antiNeop↑, 5LO↓, eff↑, HATs↓, p300↓, PCAF↓, miR-200c↑, NOTCH1↓, CSCs↓, COX2/PTGS2↓, cycD1/CCND1↓, VEGF↓, PI3K↓, Akt↓, Wnt↑, β-catenin/ZEB1↓, ROS↑, CHOP/DDIT3↑, Bax:Bcl2↑, Casp8↑, FAK↓, *neuroP↑, PCNA↓, *GSTs↑,
823- GAR,    Garcinol Potentiates TRAIL-Induced Apoptosis through Modulation of Death Receptors and Antiapoptotic Proteins
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10 - in-vitro, CRC, HCT116
Casp3↑, Casp9↑, Casp8↑, DR5↑, survivin↓, Bcl-2↓, XIAP↓, cFLIP↓, BAX↑, Cyt‑c↑, ROS↑, GSH↓, *eff↓,
7187- GBE,    Ginkgo biloba for prevention of dementia: a randomized controlled trial
- Trial, AD, NA
*Dose↝, Risk∅, eff∅,
7210- GBE,    Effectiveness and safety of ginkgo biloba preparations in the treatment of Alzheimer's disease: A systematic review and meta-analysis
- Review, AD, NA
*eff↑, *memory↑,
7218- GBE,    Efficacy and Safety of Ginkgo biloba in Patients with Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
- Review, Stroke, NA
*Stroke↓, *eff↑, *toxicity↓, *other?,
7129- Ge-132,    Antitumor activity of Ge-132, a new organogermanium compound, in mice is expressed through the functions of macrophages and T lymphocytes
- in-vivo, lymphoma, NA
eff↑,
7127- Ge-132,    Synthesis and Evaluation of Novel Organogermanium Sesquioxides As Antitumor Agents
- vitro+vivo, Var, NA
eff↑, BioAv↑, RadioS↑,
7124- Ge-132,    Physiological Activity of Trace Element Germanium including Anticancer Properties
- Review, Var, NA
*toxicity↓, Risk↓, Dose↝, AntiCan↑, AntiTum↑, Inflam↓, OXPHOS↝, *toxicity↓, *toxicity↓, other↑, eff↑, *Bacteria↓, *AntiFungal↑, eff↑, eff↑, ROS↑, eff↑, toxicity↝, *H2O2↓, *ROS↓, Warburg↓,
7098- Geld,    Geldanamycins: Potent Hsp90 Inhibitors with Significant Potential in Cancer Therapy
- Review, Var, NA
HSP90↓, *toxicity↑, *toxicity↓, *BioAv↑, eff↑, *toxicity↓, other↝,
7102- GEN,    Genistein: An Integrative Overview of Its Mode of Action, Pharmacological Properties, and Health Benefits
- Review, Var, NA
*antiOx↑, *Inflam↓, *Bacteria↓, *AntiViral↑, *Dose↝, *AntiDiabetic↑, angioG↑, Apoptosis↑, tumCV↓, MyD88↑, Beclin-1/ATG6↑, LC3II↑, TLR4↑, TumAuto↑, mTOR↓, p62↓, TumCCA↑, TumCP↓, Akt↑, P53↑, DNMT3B↓, MEK↓, hTERT/TERT↓, VEGF↓, NF-kB↓, IAP1↓, MDR1↓, p‑Akt↓, eff↑, ChemoSen↑,
1435- GEN,  SFN,    The Effects of Combinatorial Genistein and Sulforaphane in Breast Tumor Inhibition: Role in Epigenetic Regulation
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7
DNMTs↓, HDAC↓, eff↑, TumCCA↑, HMTs↓, HDAC2↓, HDAC3↓, KLF4↓, hTERT/TERT↓,
4664- GEN,  CUR,  RES,  EGCG,  SFN  Targeting cancer stem cells by nutraceuticals for cancer therapy
- Review, Var, NA
CSCs↓, other↝, eff↑, CD44↓, p‑STAT3↓,
7119- GEO2,    Germanium oxide enhances the radiosensitivity of cells
- in-vitro, Nor, CHO K1
RadioS↑, ROS↑, eff↓, DNAdam↓, Catalase∅, GSTs∅,
6564- Ger,    Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2
- in-vitro, HCC, HepG2
TumCG↓, HMG-CoA↓, TumCP↓, eff↑, Dose↝,
7115- GeS,    A phase II study of spirogermanium as second line therapy in patients with poor prognosis lymphoma. An NCI Canada Clinical Trials Group Study
- Trial, lymphoma, NA
eff↓, toxicity↝,
7291- GGB,    Inhibition of P-glycoprotein leads to improved oral bioavailability of compound K, an anticancer metabolite of red ginseng extract produced by gut microflora
- in-vivo, Nor, NA
BioAv↑, eff↑,
7286- GGB,    Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer
- in-vitro, Lung, A549 - in-vitro, Lung, PC9
Hif1a↓, Glycolysis↓, OXPHOS↑, ROS↑, Apoptosis↑, toxicity↓, PDKs↓, HK2↓, LDHA↓, PFKFB2↓, PKM2↓, eff↑,
7288- GGB,    Anti-Angiogenic Properties of Ginsenoside Rg3 Epimers: In Vitro Assessment of Single and Combination Treatments
- in-vitro, BC, MDA-MB-231
TumCMig↓, TumCP↓, Apoptosis↑, VEGF↓, AQPs↓, Akt↓, p‑mTOR↓, eff↑,
7217- GGB,    Role of Ginkgolides in the Inflammatory Immune Response of Neurological Diseases: A Review of Current Literatures
- Review, AD, NA
*eff↑, *AntiAg↑, *Apoptosis↓, *antiOx↑, *Inflam↓, *MAPK↓, *NF-kB↓, *PAF↓, *TLR1↓, *MyD88↓, *BDNF↑, *ROS↓, *PARP↓, *Cyt‑c↓,
7221- GGB,  GEM,    Ginkgolide B enhances gemcitabine sensitivity in pancreatic cancer cell lines via inhibiting PAFR/NF-кB pathway
- in-vitro, PC, NA
eff↑, NF-kB↓,
7141- GI,    Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability
- Study, Nor, BV2
*eff↑, *eff↓, *NRF2↑, *Inflam↓, *eff↑, *antiOx↑, *neuroP↑, *COX2/PTGS2↓, *NF-kB↓, *eff↓, *BioAv↝, *BioAv↑,
7142- GI,    Phase II study of the Effects of Ginger Root Extract on Eicosanoids in Colon Mucosa in People at Normal Risk for Colorectal Cancer
- Trial, Nor, NA
COX2/PTGS2↓, *PGE2↓, *5-HETE↓, *12-HETE↓, *Eic↓, *AntiCan↑, *antiOx↑, *Inflam↓, 5LO↓, eff↝,
7137- GI,    6-Shogaol from dried ginger inhibits growth of prostate cancer cells both in vitro and in vivo through inhibition of STAT3 and NF-κB signaling
- in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vitro, Pca, PC3 - vitro+vivo, Pca, HMVP2
STAT3↓, TNF-α↓, NF-kB↓, cycD1/CCND1↓, survivin↓, cMyc↓, IL7↓, RANTES↓, BAX↑, Bcl-2↓, P21↑, p27/CDKN1B↑, SOCS1↑, IRF1↑, eff↑, TumVol↓, TumW↓, toxicity↓,
7136- GI,    [6]-shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2
- vitro+vivo, NSCLC, H1650
TumCP↓, TumCCA↑, Apoptosis↑, Akt↓, EGFR↓, STAT3↓, cycD1/CCND1↓, Casp3↑, Casp7↑, TumCG↓, Ki-67↓, eff↑, Dose↝,
7157- GI,    Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials
- Review, Nor, NA
*Vomit↓, *Nausea↓, *eff↝,
7138- GI,    6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways
- vitro+vivo, BC, MDA-MB-231 - in-vitro, Pca, DU145 - in-vitro, Liver, HepG2 - in-vitro, Lung, A549
TumCP↓, TumMeta↓, p‑STAT3↓, JAK2↓, cSrc↓, JNK↑, p38↑, ERK↑, eff↓, ROS↑, cl‑PARP↑, TumCCA↑, Casp8↑, Casp9↑, Casp3↑, eff↑, Bcl-2↑, Bcl-xL↓, survivin↓, MMP9↓, COX2/PTGS2↓, IAP1↓, Dose?,
7248- Gink,    Studies on the cytotoxic mechanisms of ginkgetin in a human ovarian adenocarcinoma cell line
- in-vitro, Ovarian, OVCAR-3 - in-vitro, Cerv, HeLa - NA, NA, OV1369
Dose↝, TumCD↑, eff↓, Casp↑, H2O2↑, i-ROS↑,
7260- Gink,    Ginkgetin: A natural biflavone with versatile pharmacological activities
- Review, Var, NA - Review, Stroke, NA - Review, AD, NA
*AntiCan↑, *Inflam↓, *AntiBio↑, *neuroP↑, *TumCCA↑, Apoptosis↑, TumAuto↑, iNOS↓, COX2/PTGS2↓, PGE2↓, NF-kB↓, PLA2↓, *neuroP↑, *Stroke↓, *AntiFungal↓, *Bacteria↓, Bcl-xL↓, Bcl-2↓, Casp9↑, Casp3↑, cl‑PARP↑, IL6↓, STAT3↓, JAK1↓, survivin↓, COX2/PTGS2↓, IAP1↓, MMP2↓, MMP9↓, PTEN↑, SHP1↑, eff↑, TumVol↓, TumW↓, *toxicity↓, *ROS↓,
7265- Gink,    Ginkgetin targets GRP78 to induce dual pathways of ER stress and immune activation in osteosarcoma
- vitro+vivo, OS, NA
GRP78/BiP↓, TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, TumAuto↑, PERK↑, eIF2α↑, ATF4↑, TumCG↓, TumMeta↓, eff↑,
7280- Gins,    Pharmacokinetics of ginsenoside Rb1 and its metabolite compound K after oral administration of Korean Red Ginseng extract
- Trial, Nor, NA
*BioAv↑, *Half-Life↝, *eff↝,
4302- Gins,    Panax ginseng: A modulator of amyloid, tau pathology, and cognitive function in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *Aβ↓, *p‑tau↓, *cognitive↑, *eff↑, *PKA↑, *CREB↑, *BACE/β-secretase↓, *ADAM10↑, *MAPK↑, *ERK↑, *PI3K↑, *Akt↑, *NRF2↑, *PPARγ↓, *IDE↑, *APP↓, *PP2A↑, *memory↑,
4301- Gins,    Red Ginseng Inhibits Tau Aggregation and Promotes Tau Dissociation In Vitro
- in-vitro, AD, NA
*p‑tau↓, *eff↑, *Inflam↓,
4513- GLA,    Antineoplastic Effects of Gamma Linolenic Acid on Hepatocellular Carcinoma Cell Lines
- in-vitro, Liver, HUH7
TumCP↓, ROS↑, Apoptosis↑, HO-1↑, Trx↑, lipid-P↑, eff↓, MMP↓, DNAdam↑, selectivity↑,
4510- GLA,    Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies
- Review, NA, NA
Apoptosis↑, selectivity↑, eff↓, ROS↑, lipid-P↑, P53↑, radioP↑, chemoP↑,
7297- GlaB,    H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
- vitro+vivo, GBM, NA
TumCG↓, Glycolysis↑, lactateProd↑, Warburg↑, eff↑, Gli1↓,
7303- GoldNP,  PDT,    Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study
- Trial, Pca, NA
eff↑, PSA↓,
7308- GoldNP,    Colloidal gold: a novel nanoparticle for targeted cancer therapeutics
- Review, Var, NA
selectivity↑, eff↑,
7307- GoldNP,  Rad,    Uptake and excretion dynamics of gold nanoparticles in cancer cells and fibroblasts
- in-vitro, GBM, U87MG - in-vitro, Cerv, HeLa - in-vitro, Pca, PC3 - in-vitro, PC, Bxpc-3
eff↑,
7306- GoldNP,  Rad,    Gold nanoparticles enhance the radiation therapy of a murine squamous cell carcinoma
- in-vivo, SCC, NA
eff↑, RadioS↑,
5390- GoldNP,  GEM,  AsP,    Optimizing Gold Nanoparticles for Combination Therapy: Development of Hydrophobic Nanomedical Devices with Gemcitabine and Ascorbyl Palmitate
- in-vitro, BC, 4T1
EPR↑, eff↑,
6062- GoldNP,  SeNPs,    Nanotechnology-based Targeting of Neurodegenerative Disorders: A Promising Tool for Efficient Delivery of Neuromedicines
- Review, AD, NA
*DDS↑, *BBB↑, *eff↑,
1904- GoldNP,  AgNPs,    Unveiling the Potential of Innovative Gold(I) and Silver(I) Selenourea Complexes as Anticancer Agents Targeting TrxR and Cellular Redox Homeostasis
- in-vitro, Lung, H157 - in-vitro, BC, MCF7 - in-vitro, Colon, HCT15 - in-vitro, Melanoma, A375
TrxR↓, selectivity↑, eff↑, eff↝, ROS↑, MMP↓, Apoptosis↑, eff↑,
7320- Gos,    AT-101 Enhances the Antitumor Activity of Lenalidomide in Patients with Multiple Myeloma
- Trial, Melanoma, NA
Bcl-2↓, Mcl-1↓, Apoptosis↑, eff↑, toxicity↝, ORR↑,
7319- Gos,    BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides
- in-vitro, PC, NA
eff↑, Ca+2↑, BAX↑, Bcl-2↓, Bcl-xL↓, Mcl-1↓, RadioS↑,

Showing Research Papers: 901 to 950 of 1697
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1697

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

DDIT4↑, 1,   DIDO1/DIO-1↑, 1,   IL7↓, 1,   IRF1↑, 1,   KCNH2/hERG↓, 1,   ORR↑, 1,   PLA2↓, 1,   SRC3↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase∅, 1,   GSH↓, 1,   GSTs∅, 1,   H2O2↑, 1,   HO-1↑, 1,   lipid-P↑, 2,   OXPHOS↑, 1,   OXPHOS↝, 1,   ROS↑, 14,   i-ROS↑, 1,   Trx↑, 1,   TrxR↓, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MEK↓, 1,   MMP↓, 3,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 2,   Glycolysis↓, 1,   Glycolysis↑, 1,   HK2↓, 1,   HMG-CoA↓, 1,   lactateProd↑, 1,   LDHA↓, 1,   PDKs↓, 1,   PFKFB2↓, 1,   PKM2↓, 1,   Warburg↓, 1,   Warburg↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 4,   Akt↑, 1,   p‑Akt↓, 1,   Apoptosis↑, 11,   mt-Apoptosis↑, 1,   BAX↑, 3,   Bax:Bcl2↑, 1,   Bcl-2↓, 6,   Bcl-2↑, 1,   Bcl-xL↓, 3,   Casp↑, 1,   Casp3↑, 5,   Casp7↑, 1,   Casp8↑, 3,   Casp9↑, 3,   CBP↓, 1,   cFLIP↓, 1,   Cyt‑c↑, 1,   DR5↑, 1,   hTERT/TERT↓, 2,   IAP1↓, 3,   iNOS↓, 1,   JNK↑, 2,   p‑JNK↑, 1,   MAPK↓, 1,   Mcl-1↓, 2,   p27/CDKN1B↑, 1,   p38↑, 2,   Paraptosis↑, 1,   survivin↓, 5,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

cSrc↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

HATs↓, 2,   miR-218↑, 1,   other↑, 1,   other↝, 2,   PCAF↓, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 2,   eIF2α↑, 1,   ER Stress↑, 2,   GRP78/BiP↓, 1,   HSP90↓, 1,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 2,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   p62↓, 1,   SESN2↑, 1,   TumAuto↑, 4,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNAdam↑, 2,   DNMT3B↓, 1,   DNMTs↓, 1,   P53↑, 4,   PARP↑, 1,   cl‑PARP↑, 2,   cl‑PARP1↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 3,   P21↑, 1,   TumCCA↑, 6,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD44↓, 1,   CSCs↓, 3,   EMT↓, 1,   ERK↑, 1,   p‑ERK↑, 1,   Gli1↓, 1,   HDAC↓, 1,   HDAC2↓, 1,   HDAC3↓, 1,   HMTs↓, 1,   KLF4↓, 1,   mTOR↓, 1,   p‑mTOR↓, 1,   NOTCH1↓, 1,   p300↓, 2,   PI3K↓, 2,   PTEN↑, 1,   SHP1↑, 1,   STAT3↓, 5,   p‑STAT3↓, 2,   TumCG↓, 5,   Wnt↓, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 2,   Ca+2↑, 1,   FAK↓, 1,   Ki-67↓, 1,   miR-200c↑, 1,   MMP2↓, 1,   MMP9↓, 2,   TRIB3↑, 1,   TumCI↓, 1,   TumCMig↓, 2,   TumCP↓, 9,   TumMeta↓, 3,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 1,   ATF4↑, 1,   EGFR↓, 1,   EPR↑, 1,   Hif1a↓, 1,   VEGF↓, 4,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 5,   IL6↓, 1,   Inflam↓, 3,   JAK1↓, 1,   JAK2↓, 1,   MyD88↑, 1,   NF-kB↓, 6,   PGE2↓, 1,   PSA↓, 1,   RANTES↓, 1,   SOCS1↑, 1,   TLR4↑, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 3,   ChemoSen↑, 3,   Dose?, 1,   Dose↝, 4,   eff↓, 10,   eff↑, 34,   eff↝, 2,   eff∅, 1,   Half-Life↓, 1,   MDR1↓, 1,   RadioS↑, 4,   selectivity↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   hTERT/TERT↓, 2,   IL6↓, 1,   Ki-67↓, 1,   PSA↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   antiNeop↑, 1,   AntiTum↑, 1,   chemoP↑, 1,   radioP↑, 1,   Risk↓, 1,   Risk∅, 1,   toxicity↓, 2,   toxicity↝, 3,   TumVol↓, 2,   TumW↓, 2,  
Total Targets: 186

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

12-HETE↓, 1,   5-HETE↓, 1,   AntiBio↑, 1,   Eic↓, 1,   Nausea↓, 1,   PAF↓, 1,   Stroke↓, 2,   Vomit↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 4,   GSTs↑, 1,   H2O2↓, 1,   NRF2↑, 2,   ROS↓, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

CREB↑, 1,   PPARγ↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Apoptosis↓, 1,   Cyt‑c↓, 1,   MAPK↓, 1,   MAPK↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other?, 1,  

DNA Damage & Repair(tgid=10) ⓘ

PARP↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   PI3K↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   APP↓, 1,   PKA↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   Inflam↓, 6,   MyD88↓, 1,   NF-kB↓, 2,   PGE2↓, 1,   TLR1↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

ADAM10↑, 1,   BDNF↑, 1,   p‑tau↓, 2,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   BACE/β-secretase↓, 1,   IDE↑, 1,   PP2A↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 3,   BioAv↝, 1,   DDS↑, 1,   Dose↝, 2,   eff↓, 3,   eff↑, 8,   eff↝, 2,   Half-Life↝, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiDiabetic↑, 1,   cognitive↑, 1,   memory↑, 2,   neuroP↑, 5,   toxicity↓, 7,   toxicity↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↓, 1,   AntiFungal↑, 1,   AntiViral↑, 1,   Bacteria↓, 3,  
Total Targets: 61

Scientific Paper Hit Count for: eff, efficacy
70 Silver-NanoParticles
65 Magnetic Fields
49 Curcumin
43 Sulforaphane (mainly Broccoli)
38 Vitamin C (Ascorbic Acid)
35 Thymoquinone
33 Chemotherapy
30 immunotherapy
29 EGCG (Epigallocatechin Gallate)
28 Shikonin
26 chitosan
26 Quercetin
25 Radiotherapy/Radiation
25 Piperlongumine
24 Artemisinin
23 Resveratrol
23 Selenium NanoParticles
23 Selenite (Sodium)
22 Copper and Cu NanoParticles
22 Baicalein
22 Dichloroacetate
20 Ashwagandha(Withaferin A)
20 Berberine
18 Metformin
18 Chlorogenic acid
18 Capsaicin
18 Chrysin
18 Magnetic Field Rotating
17 Apigenin (mainly Parsley)
17 Phenylbutyrate
17 Gambogic Acid
16 Lycopene
16 diet FMD Fasting Mimicking Diet
16 Exercise
16 Bicarbonate(Sodium)
15 Selenium
15 Fisetin
14 3-bromopyruvate
14 Folic Acid, Vit B9
14 Hyperthermia
14 Citric Acid
14 Caffeic acid
14 Propolis -bee glue
14 Hydrogen Gas
14 Phenethyl isothiocyanate
13 Gold NanoParticles
13 Cisplatin
13 Formononetin
13 Honokiol
13 Ivermectin
12 Betulinic acid
12 Disulfiram
11 Auranofin
11 Fenbendazole
11 Melatonin
11 borneol
11 Vitamin D3
11 chaetocin
11 doxorubicin
11 salinomycin
11 diet Methionine-Restricted Diet
11 Dandelion Root
11 VitK3,menadione
11 Rosmarinic acid
10 Alpha-Lipoic-Acid
10 Luteolin
10 Atorvastatin
10 Boron
10 Choline
10 Vitamin K2
10 Silymarin (Milk Thistle) silibinin
10 Juglone
10 Urolithin
9 Coenzyme Q10
9 Photodynamic Therapy
9 SonoDynamic Therapy UltraSound
9 Ellagic acid
9 Carvacrol
9 Electrical Pulses
9 Eugenol
8 Vitamin B12
8 isoquercitrin
8 Chlorophyllin
8 Docosahexaenoic Acid
8 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
8 Plumbagin
8 Parthenolide
7 5-fluorouracil
7 Gemcitabine (Gemzar)
7 Docetaxel
7 buckwheat sprouts
7 isoorientin
7 Carnosic acid
7 Piperine
7 Kaempferol
7 Gossypol/AT-101
6 Allicin (mainly Garlic)
6 Dipyridamole
6 beta-glucans
6 Bifidobacterium
6 Bortezomib
6 Celastrol
6 Diclofenac
6 Fucoidan
6 Ginger/6-Shogaol/Gingerol
6 HydroxyCitric Acid
6 Spermidine
6 Inositol
6 Terpinen-4-ol / Tea Tree Oil
5 1,8-Cineole
5 Astragalus
5 chemodynamic therapy
5 Akkermansia
5 Bevacizumab (brand Avastin)
5 Aspirin
5 Ascorbyl Palmitate
5 Astaxanthin
5 Berbamine
5 beta-carotene(VitA)
5 Boswellia (frankincense)
5 Thymol-Thymus vulgaris
5 Centella asiatica / Gotu kola → asiaticoside
5 Cynaropicrin
5 eicosapentaenoic acid
5 diet Plant based
5 Lemongrass Extract/Citral
5 Echinacea
5 Ginkgo biloba-EGb 761
5 Emodin
5 MCToil
5 Gallic acid
5 Gamma-aminobutyric acid
5 Ginkgolide B
5 Magnolol
5 Licochalcone A
5 Moringa oleifera
5 Nimbolide
4 2-DeoxyGlucose
4 cetuximab
4 EMF
4 Cynara scolymus/Globe Artichoke/Artichoke Extract
4 almonertinib
4 Andrographis
4 Vitamin A, Retinoic Acid
4 α-Bisabolol / Chamomile oil
4 Butyrate
4 capecitabine
4 hydroxychloroquine
4 Cat’s Claw
4 Cannabidiol
4 CUSP9
4 erastin
4 diet Short Term Fasting
4 ferumoxytol
4 Ginseng
4 Isobavachalcone
4 iodine
4 Inulin Prebiotic
4 Isoliquiritigenin
4 itraconazole
4 Propyl gallate
4 Pterostilbene
4 Sulfasalazine
4 Whole Body Vibration
3 Anthocyanins
3 Zinc
3 Anti-oxidants
3 Sorafenib (brand name Nexavar)
3 Arsenic trioxide
3 Aloe anthraquinones
3 D-limonene
3 Biochanin A
3 Beta-Caryophyllene
3 bempedoic acid
3 Lutein
3 Zeaxanthin
3 Bufalin/Huachansu
3 temozolomide
3 Vitexin
3 Rutin
3 Bullatacin
3 Chocolate
3 Cichoric acid / Chicoric acid
3 Calorie Restriction Mimetics
3 Cysteamine
3 Oxygen, Hyperbaric
3 Geldanamycin
3 Paclitaxel/Taxol
3 Garcinol
3 Ginkgo biloba
3 Germanium Organic/Ge-132 / propagermanium (organogermanium)
3 Genistein (soy isoflavone)
3 Ginkgetin
3 Hibiscus sabdariffa
3 HydroxyTyrosol
3 isoflavones
3 lambertianic acid
3 Lecithin
3 Lactoferrin/Talactoferrin
3 nicotinamide adenine dinucleotide
3 Naringin
3 Radio Frequency
3 Taurine
3 Vitamin B1/Thiamine
2 5-Aminolevulinic acid
2 Trichostatin A
2 Glucose
2 Anethole/trans-Anethole
2 Aromatherapy
2 Trastuzumab
2 Baicalin
2 Huperzine A/Huperzia serrata
2 probiotics
2 brusatol
2 Isovitexin
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Caffeine
2 Calcium
2 carboplatin
2 Celecoxib
2 Cinnamon
2 Hydroxycinnamic-acid
2 Crocetin
2 Cucurbitacin
2 Cyclopamine
2 Dichloroacetophenone(2,2-)
2 Dasatinib/Phyrago
2 Deguelin
2 Date Fruit Extract
2 statins
2 Ferulic acid
2 Vitamin E
2 Galloflavin
2 γ-linolenic acid (Borage Oil)
2 Grapeseed extract
2 Orlistat
2 Helleborus niger extracts – Christmas Rose
2 Hyperoside
2 Potassium
2 Lapatinib
2 Lapachol
2 Licorice
2 Methylene blue
2 metronomic chemo
2 Methylsulfonylmethane
2 Mushroom Lion’s Mane
2 Niclosamide (Niclocide)
2 Phosphatidylserine
2 Rauwolfia serpentina/Indian Snakeroot
2 Aflavin-3,3′-digallate
2 tetrathiomolybdate
1 Serotonin, 5-hydroxytryptamine
1 dietMediterranean
1 Anzaroot, Astragalus fasciculifolius Bioss
1 wortmannin
1 Resiquimod
1 Aidi injection
1 Ajoene (compound of Garlic)
1 Acetyl-l-carnitine
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Amodiaquine
1 DTS(dibenzyl trisulphide) from Anamu
1 Fennel Oil/Foeniculum vulgare
1 Acer okamotoanum
1 Brucea javanica
1 Bacopa monnieri
1 Bromelain
1 Bruteridin(bergamot juice)
1 urea
1 Carnosine
1 Cannabichromene
1 Beta‐Lapachone
1 Carica papaya leaf extract
1 Camptothecin
1 irinotecan
1 Carvone
1 Polyphenols
1 Black phosphorus
1 gefitinib, erlotinib
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet Ketogenic
1 Mistletoe/Viscum album Extracts
1 Protocatechuic acid
1 PXD, phenoxodiol
1 Eurycomanone
1 Radicicol/monorden
1 flavonoids
1 Flickering Light Stimulation
1 olaparib/LYNPARZA
1 verapamil
1 Germanium inorganic
1 Geraniol
1 Germanium-Spirogermanium
1 Glabrescione B
1 Graviola
1 tamoxifen
1 High-Ozonide Oil
1 Indole-3-carbinol
1 entinostat
1 Recombinant Methioninase
1 tumor necrosis factor-related apoptosis-inducing ligand
1 Lactobacillus
1 Laetrile B17 Amygdalin
1 Linalool
1 Matrine
1 Mung Bean Sprouts
1 Methyl Jasmonate
1 methotrexate
1 Magnesium
1 Methylglyoxal
1 Mushroom Reishi
1 Myricetin
1 No Product/Mechanism Only
1 Oleocanthal
1 Peppermint
1 sericin
1 Psoralidin
1 enzalutamide
1 Rhein
1 Oxaliplatin
1 α-Santalol/Sandalwood oil
1 Scoulerine
1 polyethylene glycol
1 acetaminophen
1 acetazolamide
1 Iron
1 Squalene
1 Glutathione
1 Sutherlandioside D
1 triptolide
1 Triphala
1 Tumor Treating Fields
1 Turmerones
1 Ursolic acid
1 Vitamin B3,Niacin
1 Vitamin B5,Pantothenic Acid
1 Vitamin B6,pyridoxine
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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