BAD Cancer Research Results

BAD, BCL2 associated agonist of cell death: Click to Expand ⟱
Source:
Type:
BCL2 associated agonist of cell death (BAD) protein is a pro-apoptotic member of the Bcl-2 gene family.
Expression of the BAD is associated with the development and progression of cancer.
Scientific Papers found: Click to Expand⟱
5080- SSE,    Sodium Selenite Regulates the Proliferation and Apoptosis of Gastric Cancer Cells by Suppressing the Expression of LncRNA HOXB-AS1
- in-vitro, GC, HGC27 - in-vitro, GC, NCI-N87
AntiTum↑, HOXB-AS1↓, TumCP↓, TumCI↓, Apoptosis↑, BAD↓, Bcl-2↓, cl‑Casp3↑, MMP2↓, E-cadherin↑, N-cadherin↓, ROS↑, NF-kB↓,
5327- TFdiG,    Theaflavin-3, 3'-digallate induces apoptosis and G2 cell cycle arrest through the Akt/MDM2/p53 pathway in cisplatin-resistant ovarian cancer A2780/CP70 cells
- in-vitro, Ovarian, A2780S
TumCG↓, selectivity↑, TumCCA↑, Apoptosis↑, P53↑, BAX↑, BAD↑, cl‑Casp3↑, p‑Akt↓, MDM2↓, MMP↓, Cyt‑c↑,
2454- Trip,    Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ
- in-vitro, HNSCC, HaCaT - in-vivo, NA, NA
GSDME-N↑, Pyro↑, cMyc↓, HK2↓, BAD↑, BAX↑, Casp3↑, NRF2↓, xCT/SLC7A11↓, ROS↑, eff↑, Glycolysis↓, GlucoseCon↓, lactateProd↓, ATP↓, xCT/SLC7A11↓, eff↑,

Showing Research Papers: 51 to 53 of 53
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 53

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

NRF2↓, 1,   ROS↑, 2,   xCT/SLC7A11↓, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   MMP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   lactateProd↓, 1,  

Cell Death(tgid=5) ⓘ

p‑Akt↓, 1,   Apoptosis↑, 2,   BAD↓, 1,   BAD↑, 2,   BAX↑, 2,   Bcl-2↓, 1,   Casp3↑, 1,   cl‑Casp3↑, 2,   Cyt‑c↑, 1,   GSDME-N↑, 1,   MDM2↓, 1,   Pyro↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

HOXB-AS1↓, 1,   TumCG↓, 1,  

Migration(tgid=13) ⓘ

E-cadherin↑, 1,   MMP2↓, 1,   N-cadherin↓, 1,   TumCI↓, 1,   TumCP↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

NF-kB↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff↑, 2,   selectivity↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiTum↑, 1,  
Total Targets: 35

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: BAD, BCL2 associated agonist of cell death
4 Quercetin
4 Fisetin
3 Curcumin
3 EGCG (Epigallocatechin Gallate)
3 Eugenol
2 Berberine
2 Docetaxel
2 Gambogic Acid
2 Licochalcone A
2 Magnetic Fields
1 1,8-Cineole
1 Ashwagandha(Withaferin A)
1 immunotherapy
1 Baicalein
1 Betulinic acid
1 α-Bisabolol / Chamomile oil
1 Carvacrol
1 Thymol-Thymus vulgaris
1 Chrysin
1 Cinnamon
1 Crocetin
1 Carvone
1 Docosahexaenoic Acid
1 D-limonene
1 Citric Acid
1 Gallic acid
1 Hibiscus sabdariffa
1 Helleborus niger extracts – Christmas Rose
1 Hyperoside
1 Indole-3-carbinol
1 Juglone
1 Kaempferol
1 Luteolin
1 Magnolol
1 doxorubicin
1 Nimbolide
1 Oleuropein
1 HydroxyTyrosol
1 Propyl gallate
1 Piperine
1 Paclitaxel/Taxol
1 Arctigenin
1 α-Santalol/Sandalwood oil
1 Selenite (Sodium)
1 Aflavin-3,3′-digallate
1 triptolide
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:426  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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